植田幸嗣 (UEDA KOJI) - マイポータル

基本情報

所属: 公益財団法人がん研究会がんプレシジョン医療研究センタープロジェクトリーダー

学位: 生命科学博士(東京大学)

J-GLOBAL ID: 201601005779793325
researchmap会員ID: B000254473

外部リンク: https://kaken.nii.ac.jp/d/r/10509110.ja.html

研究キーワード

研究分野

ライフサイエンス / 腫瘍診断、治療学 /

経歴

2015年7月 - 現在

公益財団法人がん研究会がんプレシジョン医療研究センター, プロジェクトリーダー
2014年4月 - 2015年6月

東京大学大学院新領域創成科学研究科, 特任准教授
2012年4月 - 2014年3月

理化学研究所ゲノム医科学研究センター, 上級研究員
2008年4月 - 2012年3月

理化学研究所ゲノム医科学研究センター, 研究員
2005年4月 - 2008年3月

日本学術振興会特別研究員 DC1

学歴

2008年 - 現在

東京大学大学院新領域創成科学科メディカルゲノム専攻卒業（生命科学博士）
2005年 - 現在

東京大学大学院農学生命科学科応用生命化学専攻卒業（修士）
2003年 - 現在

東京大学農学部生物システム工学専攻卒業
1999年 - 現在

灘高等学校卒業

委員歴

- 現在

日本分子腫瘍マ−カー研究会世話人
- 現在

日本細胞外小胞学会（JSEV) 役員
- 現在

日本プロテオーム学会（JHUPO) 理事
- 現在

日本癌学会評議員
- 現在

Journal of Integrated OMICS (Associate Editor)
- 現在

Cancer Science (Associate Editor)
- 現在

Scientific Reports (Editorial Board Member)

受賞

2018年

日本癌学会奨励賞

植田幸嗣
2013年

理化学研究所理事長感謝状

植田幸嗣
2013年

日本ヒトプロテオーム学会（JHUPO) 奨励賞

植田幸嗣
2010年

Fellowship Award for International Workshop on Viruses, Genes and Cancer (International Workshop on Viruses, Genes and Cancer (Venice, Italy))

植田幸嗣
2008年

The Scholar-in-Training Award for the 2008 American Association for Cancer Research (AACR)

植田幸嗣
2007年

The Scholar-in-Training Award for the 2007 American Association for Cancer Research (AACR)

植田幸嗣

論文

Identification of CD14 and lipopolysaccharide-binding protein as novel biomarkers for sarcoidosis using proteomics of serum extracellular vesicles.

Yu Futami, Yoshito Takeda, Taro Koba, Ryohei Narumi, Yosui Nojima, Mari Ito, Mana Nakayama, Mimiko Ishida, Hanako Yoshimura, Yujiro Naito, Kiyoharu Fukushima, Takayuki Takimoto, Ryuya Edahiro, Takanori Matsuki, Satoshi Nojima, Haruhiko Hirata, Shohei Koyama, Kota Iwahori, Izumi Nagatomo, Yuya Shirai, Yasuhiko Suga, Shingo Satoh, Shinji Futami, Kotaro Miyake, Takayuki Shiroyama, Yoshikazu Inoue, Jun Adachi, Takeshi Tomonaga, Koji Ueda, Atsushi Kumanogoh

International immunology 34(6) 327-340 2022年6月4日
Azurocidin is loaded into small extracellular vesicles via its N‐linked glycosylation and promotes intravasation of renal cell carcinoma cells

Takuya Naito, Kentaro Jingushi, Koji Ueda, Kazutake Tsujikawa

FEBS Letters 2021年9月
Oncolytic virotherapy reverses chemoresistance in osteosarcoma by suppressing MDR1 expression.

Kazuhisa Sugiu, Hiroshi Tazawa, Joe Hasei, Yasuaki Yamakawa, Toshinori Omori, Tadashi Komatsubara, Yusuke Mochizuki, Hiroya Kondo, Shuhei Osaki, Tomohiro Fujiwara, Aki Yoshida, Toshiyuki Kunisada, Koji Ueda, Yasuo Urata, Shunsuke Kagawa, Toshifumi Ozaki, Toshiyoshi Fujiwara

Cancer chemotherapy and pharmacology 88(3) 513-524 2021年6月10日
Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis.

Satoshi Imai, Takuya Ooki, Naoko Murata-Kamiya, Daisuke Komura, Kamrunnesa Tahmina, Weida Wu, Atsushi Takahashi-Kanemitsu, Christopher Takaya Knight, Akiko Kunita, Nobumi Suzuki, Adriana A Del Valle, Mayo Tsuboi, Masahiro Hata, Yoku Hayakawa, Naomi Ohnishi, Koji Ueda, Masashi Fukayama, Tetsuo Ushiku, Shumpei Ishikawa, Masanori Hatakeyama

Cell host & microbe 29(6) 941-958 2021年6月9日
Colorectal Cancer-Derived CAT1-Positive Extracellular Vesicles Alter Nitric Oxide Metabolism in Endothelial Cells and Promote Angiogenesis.

Atsushi Ikeda, Satoshi Nagayama, Makoto Sumazaki, Makoto Konishi, Risa Fujii, Naomi Saichi, Satoshi Muraoka, Daisuke Saigusa, Hideaki Shimada, Yoshiharu Sakai, Koji Ueda

Molecular cancer research : MCR 19(5) 834-846 2021年5月
Liquid Biopsy Targeting Monocarboxylate Transporter 1 on the Surface Membrane of Tumor-Derived Extracellular Vesicles from Synovial Sarcoma.

Suguru Yokoo, Tomohiro Fujiwara, Aki Yoshida, Koji Uotani, Takuya Morita, Masahiro Kiyono, Joe Hasei, Eiji Nakata, Toshiyuki Kunisada, Shintaro Iwata, Tsukasa Yonemoto, Koji Ueda, Toshifumi Ozaki

Cancers 13(8) 2021年4月11日
G-quadruplex-forming nucleic acids interact with splicing factor 3B subunit 2 and suppress innate immune gene expression.

Kyoko Matsumoto, Keiji Okamoto, Sachiko Okabe, Risa Fujii, Koji Ueda, Kenichi Ohashi, Hiroyuki Seimiya

Genes to cells : devoted to molecular & cellular mechanisms 26(2) 65-82 2021年2月
Proteomics of serum extracellular vesicles identifies a novel COPD biomarker, fibulin-3 from elastic fibres.

Taro Koba, Yoshito Takeda, Ryohei Narumi, Takashi Shiromizu, Yosui Nojima, Mari Ito, Muneyoshi Kuroyama, Yu Futami, Takayuki Takimoto, Takanori Matsuki, Ryuya Edahiro, Satoshi Nojima, Yoshitomo Hayama, Kiyoharu Fukushima, Haruhiko Hirata, Shohei Koyama, Kota Iwahori, Izumi Nagatomo, Mayumi Suzuki, Yuya Shirai, Teruaki Murakami, Kaori Nakanishi, Takeshi Nakatani, Yasuhiko Suga, Kotaro Miyake, Takayuki Shiroyama, Hiroshi Kida, Takako Sasaki, Koji Ueda, Kenji Mizuguchi, Jun Adachi, Takeshi Tomonaga, Atsushi Kumanogoh

ERJ open research 7(1) 2021年1月
Specimen-specific drift of densities defines distinct subclasses of extracellular vesicles from human whole saliva.

Satoshi Yamamoto, Kohji Okamura, Risa Fujii, Takamasa Kawano, Koji Ueda, Yasutomo Yajima, Kiyotaka Shiba

PloS one 16(4) e0249526 2021年
Mitochondria as a Platform for Dictating the Cell Fate of Cultured Human Corneal Endothelial Cells.

Kohsaku Numa, Morio Ueno, Tomoko Fujita, Koji Ueda, Nao Hiramoto, Atushi Mukai, Yuichi Tokuda, Masakazu Nakano, Chie Sotozono, Shigeru Kinoshita, Junji Hamuro

Investigative ophthalmology & visual science 61(14) 10-10 2020年12月1日
腎臓由来循環エキソソームの自動分離技術の開発と大規模検証研究への応用

大西なおみ, 塩澤久美子, 神宮司健太郎, 植村元秀, 中田渡, 藤田和利, 内藤拓也, 野々村祝夫, 辻川和丈, 植田幸嗣

日本癌学会総会記事 79回 OJ15-1 2020年10月
腎臓由来循環エキソソームの自動分離技術の開発と大規模検証研究への応用

大西なおみ, 塩澤久美子, 神宮司健太郎, 植村元秀, 中田渡, 藤田和利, 内藤拓也, 野々村祝夫, 辻川和丈, 植田幸嗣

日本癌学会総会記事 79回 OJ15-1 2020年10月
Multiresolution Imaging Using Bioluminescence Resonance Energy Transfer Identifies Distinct Biodistribution Profiles of Extracellular Vesicles and Exomeres with Redirected Tropism.

Anthony Yan-Tang Wu, Yun-Chieh Sung, Yen-Ju Chen, Steven Ting-Yu Chou, Vanessa Guo, Jasper Che-Yung Chien, John Jun-Sheng Ko, Alan Ling Yang, Hsi-Chien Huang, Ju-Chen Chuang, Syuan Wu, Meng-Ru Ho, Maria Ericsson, Wan-Wan Lin, Chantal Hoi Yin Cheung, Hsueh-Fen Juan, Koji Ueda, Yunching Chen, Charles Pin-Kuang Lai

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 7(19) 2001467-2001467 2020年10月
Polarized Expression of Ion Channels and Solute Carrier Family Transporters on Heterogeneous Cultured Human Corneal Endothelial Cells.

Junji Hamuro, Hideto Deguchi, Tomoko Fujita, Koji Ueda, Yuichi Tokuda, Nao Hiramoto, Kohsaku Numa, Masakazu Nakano, John Bush, Morio Ueno, Chie Sotozono, Shigeru Kinoshita

Investigative ophthalmology & visual science 61(5) 47-47 2020年5月11日
Pathological processes in aqueous humor due to iris atrophy predispose to early corneal graft failure in humans and mice.

Takefumi Yamaguchi, Kazunari Higa, Yukari Yagi-Yaguchi, Koji Ueda, Hisashi Noma, Shinsuke Shibata, Toshihiro Nagai, Daisuke Tomida, Ririko Yasu-Mimura, Osama Ibrahim, Ryo Matoba, Kazuo Tsubota, Pedram Hamrah, Jun Yamada, Kohsuke Kanekura, Jun Shimazaki

Science advances 6(20) eaaz5195 2020年5月
Metabolites Interrogation in Cell Fate Decision of Cultured Human Corneal Endothelial Cells.

Junji Hamuro, Kohsaku Numa, Tomoko Fujita, Munetoyo Toda, Koji Ueda, Yuichi Tokuda, Atushi Mukai, Masakazu Nakano, Morio Ueno, Shigeru Kinoshita, Chie Sotozono

Investigative ophthalmology & visual science 61(2) 10-10 2020年2月7日
前立腺癌特異的PSA糖鎖構造の同定による新規な前立腺癌診断アルゴリズムPSA G-Indexの構築(Establishment of a diagnostic model PSA G-Index as a non-invasive secondary screening biomarker for prostate cancer)

芳賀淑美, 植村元秀, 赤松秀輔, 稲村健太郎, 竹内賢吾, 小川修, 野々村祝夫, 植田幸嗣

日本癌学会総会記事 78回 P-1386 2019年9月
INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4.

Yu-Yu Liu, Chizu Tanikawa, Koji Ueda, Koichi Matsuda

International journal of oncology 54(6) 1907-1920 2019年6月査読有り
Identification of Multisialylated LacdiNAc Structures as Highly Prostate Cancer Specific Glycan Signatures on PSA.

Yoshimi Haga, Motohide Uemura, Satoko Baba, Kentaro Inamura, Kengo Takeuchi, Norio Nonomura, Koji Ueda

Analytical chemistry 91(3) 2247-2254 2019年2月5日査読有り
Prospective exosome-focused translational research for afatinib study of non-small cell lung cancer patients expressing EGFR (EXTRA study).

Yusuke Okuma, Kei Morikawa, Hisashi Tanaka, Takuma Yokoyama, Hidetoshi Itani, Kazuya Horiuchi, Hideyuki Nakagawa, Nobumasa Takahashi, Akihiro Bessho, Kenzo Soejima, Kazuma Kishi, Akira Togashi, Yae Kanai, Koji Ueda, Katsuhisa Horimoto, Noriyuki Matsutani, Nobuhiko Seki

Thoracic cancer 10(2) 395-400 2019年2月

もっとみる

MISC

Effects of SMYD2-mediated EML4-ALK methylation on the signaling pathway and growth in non-smallcell lung cancer cells

Rui Wang, Xiaolan Deng, Yuichiro Yoshioka, Theodore Vougiouklakis, Jae-Hyun Park, Takehiro Suzuki, Naoshi Dohmae, Koji Ueda, Ryuji Hamamoto, Yusuke Nakamura

CANCER SCIENCE 109 1217-1217 2018年12月
Identification of Circulating Exosomal Marker in Synovial Sarcoma

Suguru Yokoo, Tomohiro Fujiwara, Aki Yoshida, Masahiro Kiyono, Yusuke Mochizuki, Koji Demiya, Joe Hasei, Toshiyuki Kunisada, Yusuke Yoshioka, Koji Ueda, Takahiro Ochiya, Toshifumi Ozaki

CANCER SCIENCE 109 570-570 2018年12月
Liquid biopsy using tumor-derived exosomes for Ewing sarcoma patients

Aki Yoshida, Tomohiro Fujiwara, Koji Uotani, Shintaro Iwata, Yusuke Yoshioka, Koji Ueda, Takuya Morita, Masahiro Kiyono, Suguru Yokoo, Joe Hasei, Toshiyuki Kunisada, Takahiro Ochiya, Toshifumi Ozaki

CANCER SCIENCE 109 312-312 2018年1月
Development of our novel method to analyze cancer-derived circulating exosomes

Motohide Uemura, Kentaro Jingushi, Kazutoshi Fujita, Norio Nonomura, Kazutake Tsujikawa, Koji Ueda

CANCER SCIENCE 109 18-18 2018年1月
Regulation of RNA processing by PADI4 pathway

Chizu Tanikawa, Koji Ueda, Yusuke Nakamura, Koichi Matsuda

CANCER RESEARCH 75 2015年8月
A three-factor plasma diagnostic model of human T -cell leukemia virus-1 associated myelopathy

Makoto Ishihara, Natsumi Araya, Tomoo Sato, Naomi Saichi, Risa Fujii, Yoshihisa Yamano, Koji Ueda

RETROVIROLOGY 12 2015年8月
Proteomic analysis of citrullinated targets regulated by the p53-PADI4 pathway

Chizu Tanikawa, Koji Ueda, Hidewaki Nakagawa, Yusuke Nakamura, Koichi Matsuda

CANCER RESEARCH 74(19) 2014年10月
GALNT6 stabilizes GRP78 protein by O-type glycosylation

Jae-Hyun Park, Suyoun Chung, Jiaying Lin, Koji Ueda, Toyomasa Katagiri, Yusuke Nakamura

CANCER RESEARCH 74(19) 2014年10月
Orally administrative melk (maternal embryonic leucine zipper kinase)-targeting small molecule inhibitor suppresses the growth of various types of human cancer.

Suyoun Chung, Hanae Suzuki, Takashi Miyamoto, Naofumi Takamatsu, Ayako Tatsuguchi, Koji Ueda, Kyoko Kijima, Yo Matsuo, Yusuke Nakamura

JOURNAL OF CLINICAL ONCOLOGY 31(15) 2013年5月
Development of an orally-administrative MELK (maternal embryonic leucine zipper kinase)-targeting small molecule inhibitor that suppresses the growth of various types of human cancer.

Suyoun Chung, Hanae Suzuki, Takashi Miyamoto, Naofumi Takamatsu, Ayako Tatsuguchi, Koji Ueda, Kyoko Kijima, Yo Matsuo, Yusuke Nakamura

CANCER RESEARCH 73(8) 2013年4月
A focused proteomics technology QUEST-MS identified a novel plasma prostate cancer biomarker polypeptide complementing PSA test

Koji Ueda, Ayako Tatsuguchi, Kenji Tamura, Taro Shuin, Masato Nakayama, Taka-Aki Sato, Yusuke Nakamura, Hidewaki Nakagawa

CANCER RESEARCH 72 2012年4月
Quantitative proteome profiling of CD4+CD25+CCR4+T-cells to identify potential therapeutic targets for adult T-cell leukemia (ATL) and Human T-lymphotropic virus type-1 associated myelopathy (HAM)

Ishihara Makoto, Natsumi Araya, Tomoo Sato, Atae Utsunomiya, Yoshihisa Yamano, Yusuke Nakamura, Hidewaki Nakagawa, Koji Ueda

CANCER RESEARCH 72 2012年4月
Development of serum glycoproteomic profiling technology for the identification of pancreatic cancer biomarkers: simultaneous identification of glycosylation sites and site-specific quantification of glycan structure changes

Koji Ueda, Hidewaki Nakagawa, Naomi Saichi, Masaru Katsumata, Taka-Aki Sato, Yusuke Nakamura

CANCER RESEARCH 70 2010年4月
Development of serum glycoproteomic profiling technology for the identification of pancreatic cancer biomarkers: simultaneous identification of glycosylation sites and site-specific quantification of glycan structure changes

Koji Ueda, Hidewaki Nakagawa, Naomi Saichi, Masaru Katsumata, Taka-Aki Sato, Yusuke Nakamura

CANCER RESEARCH 70 2010年4月
Serum proteome analysis by label-free quantification system and LC-MALDI mass spectrometry for the discovery of novel biomarkers for lung cancer

Atsuhiko Toyama, Koji Ueda, Hidewaki Nakagawa, Yataro Daigo, Taka-Aki Sato, Yusuke Nakamura

CANCER RESEARCH 70 2010年4月
Serum glycoproteomic profiling using IGEL (isotopic glycosidase elution and tagging from lectin column chromatography) method: discovery of carbohydrate-targeting tumor markers for lung cancer

Koji Ueda, Hidewaki Nakagawa, Yataro Daigo, Nobuhisa Ishikawa, Nobuoki Kohno, Yusuke Nakamura

CANCER RESEARCH 69 2009年5月

植田幸嗣

基本情報

研究キーワード

研究分野

経歴

学歴

委員歴

受賞

論文

MISC

所属学協会

メニュー

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