Koki Hasegawa

Profile Information

J-GLOBAL ID: 201101050410238792
researchmap Member ID: B000219003

External link: http://kaken.nii.ac.jp/ja/r/50525798

Research Interests

Research Areas

Research History

Apr, 2021 - Present

School of Health Sciences, Fukushima Medical University
Oct, 2015 - Mar, 2021

Instrumental Analysis Center, Kyoto Pharmaceutical University
May, 2012 - Sep, 2015

Kumamoto University
Apr, 2008 - Apr, 2012

RIKEN
Oct, 2002 - Sep, 2003

Institute for Protein Research, Osaka University

Education

Apr, 2004 - Mar, 2008

School of Dentistry, School of Dentistry, Osaka University
Apr, 1997 - Sep, 2002

化学, 理学研究科, 大阪大学大学院
Apr, 1993 - Mar, 1997

Himeji Institute of Technology

Major Papers

Facile synthesis of 2-deoxy-2-[18 F]fluorosorbitol using sodium borohydride on aluminum oxide.

Koki Hasegawa, Kazuhiro Koshino, Takahiro Higuchi

Journal of labelled compounds & radiopharmaceuticals, 64(1) 40-46, Jan, 2021 Peer-reviewedLead authorCorresponding author
Kiss1R Identification and Biodistribution Analysis Employing a Western Ligand Blot and Ligand-Derivative Stain with a FITC-Kisspeptin Derivative.

Koki Hasegawa, Rika Maedomari, Younosuke Sato, Kumiko Gotoh, Shinji Kudoh, Akihiro Kojima, Seiji Okada, Takaaki Ito

ChemMedChem, 15(18) 1699-1705, Sep 16, 2020 Peer-reviewedLead authorCorresponding author
Somatostatin receptor staining in FFPE sections using a ligand derivative dye as an alternative to immunostaining.

Koki Hasegawa, Shinji Kudoh, Takaaki Ito

PloS one, 12(2) e0172030-e0172030, 2017 Peer-reviewedLead authorCorresponding author
Improved 68 Ga-labeling method using ethanol addition: Application to the α-helical peptide DOTA-FAMP.

Koki Hasegawa, Emi Kawachi, Yoshinari Uehara, Tsuyoshi Yoshida, Satoshi Imaizumi, Masahiro Ogawa, Shin-Ichiro Miura, Keijiro Saku

Journal of labelled compounds & radiopharmaceuticals, 60(1) 55-61, Jan, 2017 Peer-reviewedLead authorCorresponding author

Misc.

Discussion on Translational Research of Drug Product for Targeted Alpha Therapy-Part 8-Discussion on Targeted Alpha Therapy for Viral Infection

矢野恒夫, 淵上剛志, 高橋豊, 角永悠一郎, 長谷川功紀, 加藤弘樹, 渡部直史, 樺山一哉, 山村朝雄, 佐藤達彦 …

Pharm Tech Japan, 38(13), 2022
Discussion on Translational Research of Drug Product for Targeted Alpha Therapy-Part 7--Aiming for Practical Use of Targeted Alpha Therapy (TAT) based on Nanomedicine while Understanding an Abscopal treatment response and a Random walk approach deeply-

矢野恒夫, 角永悠一郎, 樺山一哉, 加藤弘樹, 高橋豊, 山村朝雄, 長谷川功紀, 佐藤達彦, 佐藤達彦, 淵上剛志 …

Pharm Tech Japan, 38(2) 281-289, 2022
アルファ線核医学治療のための薬剤開発の考察(その7) 足元を固めながらナノメディシンTATの実用化を目指して(前編)

矢野恒夫, 角永悠一郎, 樺山一哉, 加藤弘樹, 高橋豊, 山村朝雄, 長谷川功紀, 佐藤達彦, 淵上剛志, 渡部直史 …

PHARM TECH JAPAN, 38(1) 81-86, Jan, 2022
ポリプロリンヘリックスIIヘリックス構造によるアルギニンペプチドの細胞膜透過性の亢進

松井早希, 岡田圭祐, 竹内美紗紀, 扇田隆司, 原矢佑樹, 西辻和親, 内村健司, 長谷川功紀, 加藤くみ子, 赤路健一 …

日本薬学会年会要旨集, 140年会 27P-am067S, Mar, 2020
67Ga標識Reactive Black 5を利用した炎症巣のSPECTイメージング

斎藤恵里佳, 安東友繁, 服部恭尚, 長谷川功紀

日本薬学会年会要旨集, 140年会 27P-pm183S, Mar, 2020
ポリプロリンIIヘリックス構造によるアルギニンペプチド細胞膜透過促進機構

扇田隆司, 原矢佑樹, 岡田圭祐, 松井早希, 竹内美紗紀, 齋藤千尋, 西辻和親, 内村健治, 川野竜司, 長谷川功紀 …

膜シンポジウム, (32), 2020
タモキシフェン誘導体を用いた肺がんのリガンド誘導体染色

長谷川功紀, 井上康輝, 工藤信次, 伊藤隆明

日本組織細胞化学会総会・学術集会講演プログラム・予稿集, 60回 88-88, Sep, 2019
ApoE糖鎖結合ドメイン改変型両親媒性アルギニンペプチドの細胞膜透過機構

小谷真菜, 田村悠樹, 扇田隆司, 原矢佑樹, 西辻和親, 内村健治, 長谷川功紀, 加藤くみ子, 赤路健一, 斎藤博幸

日本薬学会年会要旨集(CD-ROM), 139th(2) ROMBUNNO.22PO‐am128S-249, Mar, 2019
ApoE糖鎖結合ドメイン改変型両親媒性アルギニンペプチドの細胞膜透過機構

小谷真菜, 田村悠樹, 扇田隆司, 原矢佑樹, 西辻和親, 内村健治, 長谷川功紀, 加藤くみ子, 赤路健一, 斎藤博幸

日本薬学会年会要旨集, 139年会(2) 249-249, Mar, 2019
病理組織切片上のGPER検出薬剤の開発

長谷川功紀, 工藤信次, 伊藤隆明

日本薬学会年会要旨集, 139年会(3) 58-58, Mar, 2019
国内未承認RI内用療法に関する海外動向ならびに国内導入に向けたニーズ・問題点に関する調査研究

福島和人, 高野祥子, 長谷川功紀, 野上宗伸, 日向信之, 樋口隆弘

核医学, 55(Suppl.) S154-S154, Nov, 2018
アルファ線核医学治療の薬剤開発に向けた取扱安全基準構築への考察

長谷川功紀, 深瀬浩一, 矢野恒夫

核医学, 55(Suppl.) S183-S183, Nov, 2018
低分子リガンドを用いたエストロゲン受容体検出法の開発

長谷川功紀, 工藤信次, 伊藤隆明

日本組織細胞化学会総会・学術集会講演プログラム・予稿集, 59回 57-57, Sep, 2018
肺癌における新しいガイダンス分子であるドラキシンについて

佐藤陽之輔, 松尾顕, 工藤信次, 長谷川功紀, 長谷川功紀, 伊藤隆明

日本病理学会会誌, 107(1) 296‐297-297, Apr 26, 2018
肺癌における新しいガイダンス分子であるドラキシンについて

佐藤陽之輔, 松尾顕, 工藤信次, 長谷川功紀, 伊藤隆明

日本病理学会会誌, 107(1) 296-297, Apr, 2018
新規両親媒性アルギニンペプチドの細胞膜透過性の評価

田村悠樹, 灘井亮, 扇田隆司, 原矢佑樹, 西辻和親, 内村健治, 長谷川功紀, 加藤くみ子, 赤路健一, 斎藤博幸

日本薬学会年会要旨集(CD-ROM), 138th(2) ROMBUNNO.27PA‐am280S-253, Mar, 2018
新規両親媒性アルギニンペプチドの細胞膜透過性の評価

田村悠樹, 灘井亮, 扇田隆司, 原矢佑樹, 西辻和親, 内村健治, 長谷川功紀, 加藤くみ子, 赤路健一, 斎藤博幸

日本薬学会年会要旨集, 138年会(2) 253-253, Mar, 2018
エストラジオール誘導体を用いたその受容体検出法の開発

長谷川功紀, 工藤信次, 伊藤隆明

日本薬学会年会要旨集, 138年会(3) 158-158, Mar, 2018
リガンド誘導体染色によるソマトスタチン受容体の検出法

工藤信次, 長谷川功紀, 中峰ともみ, 伊藤隆明

日本臨床細胞学会雑誌, 56(Suppl.2) 896-896, Oct, 2017
リガンド誘導体染色法を用いたKisspeptin Receptor(KISS1R)の検出検討

前泊里佳, 長谷川功紀, 伊藤隆明

日本組織細胞化学会総会・学術集会講演プログラム・予稿集, 58回 67-67, Sep, 2017

Books and Other Publications

Handbook of in vivo chemistry in mice : from lab to living system

Tanaka, Katsunori, Vong, Kenward

Wiley-VCH, 2020 (ISBN: 9783527344321)
医療・診断をささえるペプチド科学 : 再生医療・DDS・診断への応用

平野, 義明

シーエムシー出版, Oct, 2017 (ISBN: 9784781312675)
次世代ペプチド医薬創製

赤路, 健一

メディカルドゥ, Aug, 2014 (ISBN: 9784944157686)
創薬研究への分子イメージング応用

佐治, 英郎

メディカルドゥ, Dec, 2010 (ISBN: 9784944157488)
創薬技術の革新 : マイクロドーズからPET分子イメージングへの新展開

杉山, 雄一, 山下, 伸二, 栗原, 千絵子

メディカルドゥ, Oct, 2010 (ISBN: 9784944157808)

Presentations

Target identification in pathological tissues using peptide probes

May 20, 2023 Invited
Exploration of imaging targets using pathological tissues

Invited

Teaching Experience

Apr, 2023 - Present

Safeties of Patients and Medical Devices (Fukushima Medical University)
Apr, 2023 - Present

Nuclear medicine pharmacology (Fukushima Medical University)
Apr, 2023 - Present

Labolatry in nuclear medicine technique (Fukushima Medical University)
Apr, 2022 - Present

Laboratory in Basic Radiation Sciences (Fukushima Medical University)
Apr, 2021 - Present

Practice of histology (Fukushima Medical University)
Apr, 2021 - Present

Histology (Fukushima Medical University)
Apr, 2021 - Present

Basic radiation sciences (Fukushima Medical University)
Apr, 2018 - Mar, 2021

Pharmaceutical Research A (Kyoto Pharmaceutical University)
Apr, 2016 - Mar, 2021

Comprehensive Pharmaceutical Exercise (Kyoto Pharmaceutical University)
Apr, 2016 - Mar, 2021

Basic Seminar (Kyoto Pharmaceutical University)
分子イメージング講義 (岡山大学)
大学院医学実験講座 (熊本大学)
病理学実習 (熊本大学)

Professional Memberships

Jan, 2023 - Present

European Association of Nuclear Medicine
Apr, 2021 - Present

Japanese society for Radiological Technology
2021 - Present

日本癌学会
2016 - Present

JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY
2016 - Present

THE JAPANESE SOCIETY OF PATHOLOGY
Jan, 2011 - Present

Society of Radiopharmaceutical Sciences
2008 - Present

THE JAPANESE SOCIETY OF NUCLEAR MEDICINE
2008 - Present

THE PHARMACEUTICAL SOCIETY OF JAPAN
2007 - Present

The Japanese Peptide Society

Research Projects

Development of alpha-ray microdosimetry at the cellular level

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2023 - Mar, 2026
Genetic basis of individual differences in itch sensitivity using mouse strain differences

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2022 - Mar, 2025
Signal molecules of ASCL1, a lineage-specific transcription factor for small cell carcinoma of the lung

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2020 - Mar, 2024
Development of a method to predict prognosis and treatment effect based on estrogen receptor expression level

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2020

Hasegawa Koki
Construction of heart failure personalized medicine strategy by heart molecular imaging international collaborative research

Grants-in-Aid for Scientific Research Fund for the Promotion of Joint International Research (Home-Returning Researcher Development Research), Fund for the Promotion of Joint International Research (Home-Returning Researcher Development Research), Japan Society for the Promotion of Science, 2016 - 2019

HIGUCHI Takahiro, FUKUSHIMA Kazuhito, KIMURA Hiroyuki, HASEGAWA Koki, FUKUCHI Kazuki, SAITO Shigeyoshi, FUKUSHIMA Kenji, ZENIYA Tsutomu, NAKAJIMA Kenichi, TAKI Junichi, YAMAYA Taiga, TORIUMI Fujio, SHIOYA Kyoko
Regulation of small cell lung carcinoma cells by interference between axon guidance molecules and their receptors

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2018

Ito Takaaki, MATSUO Akira, SHINMYO Yohei, HASEGAWA Koki
Relationship between receptor expression revaled by rhodamine-labeled peptides and calcium responses in cortical neurons

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2018

KOBAYASHI Masayuki
Development of multimodal theranostics tracer for personalized medicine in immuno-oncology

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Kubo Hitoshi, NAKAMURA Michihiro, HASEGAWA Koki
Establishment of novel immunoPET/MRI using 64cU

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Honda Hiroshi
Development of the stainier and SPECT probe for the diagnosis of CXCR4 expression in small cell lung carcinoma

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

Hasegawa Koki
Mechanisms on genesis of combined type small cell carcinoma; a study focusing on Notch signaling

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

Ito Takaaki, NIIMORI Kanako, HASEGAWA Koki
Search for the PET probes and comparison between them towards non-invasive beta cell mass measurement in human

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2011 - Mar, 2015

SAKO Takeo, HASEGAWA Koki, KATAOKA Yousuke, CUI Yilong, TOYODA Hiroshi, NISHIMURA Mie, HAYASHINAKA Emi, WADA Yasuhiro
Development of a novel site-specific 18F protein labeling method and application for synthesis of 18F-EGF

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, 2011 - 2013

HASEGAWA Koki
Pancreatic β cell imaging using 64Cu- or 68Ga-labeled Exendin-4

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, 2009 - 2010

HASEGAWA Koki

Industrial Property Rights

特許第5892540号生体内にて標的組織に指向する放射標識化合物およびその利用

渡辺恭良, 長谷川功紀
特許第5721106号膵臓内分泌細胞用指示薬、及びその利用

渡辺恭良, 佐古健生, 長谷川功紀, 金山洋介, 片岡洋祐
特許第5013378号新規ヘキサトリエン−β−カルボニル化合物

深瀬浩一, 田中克典, 渡辺恭良, 田原強, 長谷川功紀
WO2011-078250 生体内にて標的組織に指向する放射標識化合物およびその利用

渡辺恭良, 長谷川功紀
WO2011-013703 膵臓内分泌細胞用指示薬、及びその利用

渡辺恭良, 佐古健生, 長谷川功紀, 金山洋介, 片岡洋祐
WO2010-041742 DOTAの導入法

長谷川功紀, 渡辺恭良
WO2008-096760 新規ヘキサトリエン−β−カルボニル化合物

深瀬浩一, 田中克典, 渡辺恭良, 田原強, 長谷川功紀

Profile Information

Research Interests

Research Areas

Research History

Education

Major Papers

Misc.

Books and Other Publications

Presentations

Teaching Experience

Professional Memberships

Research Projects

Industrial Property Rights

Menu

Coauthors