Koshi Imami

Profile Information

Affiliation: Unit Leader, IMS, RIKEN
: (Visiting professor), Graduate School of Pharmaceutical Sciences, Kyoto University
: (Visiting professor), Tokyo Medical and Dental University

Degree: Ph.D.(Keio University)

J-GLOBAL ID: 201601008795140691
researchmap Member ID: B000256483

External link: https://scholar.google.de/citations?user=JnAfF8wAAAAJ&hl=en

Research Interests

Research Areas

Life sciences / Systems genomics /

Research History

Apr, 2024 - Present

Adjunct Professor, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
Apr, 2024 - Present

Adjunct Professor, Graduate School of Pharmaceutical Sciences, Kyoto University
Apr, 2023 - Present

Unit Leader, Center for Integrative Medical Sciences (IMS), RIKEN
Apr, 2022 - Mar, 2023

Senior Scientist, RIKEN Center for Integrative Medical Sciences, RIKEN
Oct, 2018 - Mar, 2022

PRESTO Researcher, Japan Science and Technology Agency
Nov, 2017 - Mar, 2022

Project assistant professor, Graduate School of Pharmaceutical Sciences, Kyoto University
May, 2013 - Oct, 2017

Scientist, Max Delbrück Center for Molecular Medicine (MDC)
May, 2013 - Apr, 2015

JSPS Overseas Postdoctral Fellow, Japan Society for the Promotion of Science
Jul, 2010 - Apr, 2015

Postdoctral Fellow, Centre For High-Throughput Biology (CHiBi), University of British Columbia
Apr, 2009 - Mar, 2011

JSPS Research Fellow, Japan Society for the Promotion of Science

Education

Committee Memberships

Jan, 2024 - Present

Director, Japanese Proteomics Society (JPrOS)
2021 - 2022

Review Board for Research Fellowship for Young Scientists, JSPS

Major Awards

Nov, 2022

Young Investigator Award 2022, The Japanese Biochemical Society

Koshi Imami
Sep, 2019

16th Kakiuchi Saburo memorial research award, The Japanese Biochemical Society

Koshi Imami
Jul, 2019

Incentive Award 2019, Japan Proteome Society

Koshi Imami
Nov, 2010

9th Science and Technology award, Yamagata Prefecture

Koshi Imami

Papers

Pathogenic mutations of human phosphorylation sites affect protein–protein interactions

Trendelina Rrustemi, Katrina Meyer, Yvette Roske, Bora Uyar, Altuna Akalin, Koshi Imami, Yasushi Ishihama, Oliver Daumke, Matthias Selbach

Nature Communications, Apr 11, 2024
One-step N-terminomics based on isolation of protein N-terminal peptides from LysargiNase digests by tip-based strong cation exchange chromatography

Kazuya Morikawa, Hiroshi Nishida, Koshi Imami, Yasushi Ishihama

Feb 7, 2024
Exploring protein lipidation by mass spectrometry-based proteomics.

Kazuya Tsumagari, Yosuke Isobe, Koshi Imami, Makoto Arita

Journal of biochemistry, Dec 15, 2023
Application of Liquid-Liquid Extraction for N-terminal Myristoylation Proteomics.

Kazuya Tsumagari, Yosuke Isobe, Yasushi Ishihama, Jun Seita, Makoto Arita, Koshi Imami

Molecular & cellular proteomics : MCP, 22(12) 100677-100677, Nov 9, 2023
UGGT1/2-mediated reglucosylation ofN-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins

Satoshi Ninagawa, Masaki Matsuo, Deng Ying, Shinya Aso, Kazutoshi Matsushita, Akane Fueki, Shunsuke Saito, Koshi Imami, Yasuhiko Kizuka, Tetsushi Sakuma …

Oct 19, 2023
Znf598-mediated Rps10/eS10 ubiquitination contributes to the ribosome ubiquitination dynamics during zebrafish development

Nozomi Ugajin, Koshi Imami, Hiraku Takada, Yasushi Ishihama, Shinobu Chiba, Yuichiro Mishima

RNA, rna.079633.123-rna.079633.123, Sep 26, 2023
TurboID-EV: Proteomic Mapping of Recipient Cellular Proteins Proximal to Small Extracellular Vesicles

Yuka Li, Eisuke Kanao, Tomoyoshi Yamano, Yasushi Ishihama, Koshi Imami

Analytical Chemistry, Sep 14, 2023
Rapid and Highly Efficient Purification of Extracellular Vesicles Enabled by a TiO₂ Hybridized Spongy-like Polymer

Eisuke Kanao, Koki Ishida, Ryosuke Mizuta, Yuka Li, Koshi Imami, Tetsuya Tanigawa, Yoshihiro Sasaki, Kazunari Akiyoshi, Jun Adachi, Koji Otsuka …

Analytical Chemistry, Sep 13, 2023
One thousand samples per day capillary-flow LC/MS/MS for high-speed, high-sensitivity and in-depth proteomics

Ayana Tomioka, Ryota Tomioka, Issei Mori, Yosuke Isobe, Makoto Arita, Koshi Imami, Eisuke Kanao, Kosuke Ogata, Yasushi Ishihama

Jun 7, 2023
Bioinertization of nanoLC/MS/MS systems by depleting metal ions from the mobile phases for phosphoproteomics.

Yumi Komori, Tomoya Niinae, Koshi Imami, Jun Yanagibayashi, Kenichi Yasunaga, Shinya Imamura, Masami Tomita, Yasushi Ishihama

Molecular & cellular proteomics : MCP, 22(5) 100535-100535, Mar 21, 2023
Monitoring mitochondrial translation by pulse SILAC.

Koshi Imami, Matthias Selbach, Yasushi Ishihama

The Journal of biological chemistry, 299(2) 102865-102865, Feb, 2023
Classification of Extracellular Vesicles Based on Surface Glycan Structures by Spongy-like Separation Media.

Eisuke Kanao, Shuntaro Wada, Hiroshi Nishida, Takuya Kubo, Tetsuya Tanigawa, Koshi Imami, Asako Shimoda, Kaori Umezaki, Yoshihiro Sasaki, Kazunari Akiyoshi …

Analytical chemistry, 94(51) 18025-18033, Dec 13, 2022
A critical period of translational control during brain development at codon resolution.

Dermot Harnett, Mateusz C Ambrozkiewicz, Ulrike Zinnall, Alexandra Rusanova, Ekaterina Borisova, Amelie N Drescher, Marta Couce-Iglesias, Gabriel Villamil, Rike Dannenberg, Koshi Imami …

Nature structural & molecular biology, Dec 8, 2022
Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.

Heathcliff Dorado García, Fabian Pusch, Yi Bei, Jennifer von Stebut, Glorymar Ibáñez, Kristina Guillan, Koshi Imami, Dennis Gürgen, Jana Rolff, Konstantin Helmsauer …

Nature communications, 13(1) 4297-4297, Jul 25, 2022
pSNAP: Proteome-wide analysis of elongating nascent polypeptide chains

Junki Uchiyama, Rohini Roy, Dan Ohtan Wang, Kazuya Morikawa, Yuka Kawahara, Mio Iwasaki, Chiaki Yoshino, Yuichiro Mishima, Yasushi Ishihama, Koshi Imami

iScience, 25(7) 104516-104516, Jun, 2022 Peer-reviewed
Cyclin J-CDK complexes limit innate immune responses by reducing proinflammatory changes in macrophage metabolism.

Yee Kien Chong, Sarang Tartey, Yuki Yoshikawa, Koshi Imami, Songling Li, Masanori Yoshinaga, Ai Hirabayashi, Guohao Liu, Alexis Vandenbon, Fabian Hia …

Science signaling, 15(729) eabm5011, Apr 12, 2022
ABIN1 is a signal-induced autophagy receptor that attenuates NF-κB activation by recognizing linear ubiquitin chains.

Yutaka Shinkawa, Koshi Imami, Yasuhiro Fuseya, Katsuhiro Sasaki, Koichiro Ohmura, Yasushi Ishihama, Akio Morinobu, Kazuhiro Iwai

FEBS letters, 596(9) 1147-1164, Feb 25, 2022
Biotinylation-based proximity labeling proteomics: Basics, applications, and technical considerations.

Tomoya Niinae, Yasushi Ishihama, Koshi Imami

Journal of biochemistry, 170(5) 569-576, Nov 9, 2021
Peptide probes containing a non-hydrolyzable phosphotyrosine-mimetic residue for enrichment of protein tyrosine phosphatases.

Kazuya Tsumagari, Tomoya Niinae, Akira Otaka, Yasushi Ishihama

Proteomics, 44th e2100144, Oct 29, 2021
Combinatorial analysis of translation dynamics reveals eIF2 dependence of translation initiation at near-cognate codons.

Kazuya Ichihara, Akinobu Matsumoto, Hiroshi Nishida, Yuki Kito, Hideyuki Shimizu, Yuichi Shichino, Shintaro Iwasaki, Koshi Imami, Yasushi Ishihama, Keiichi I Nakayama

Nucleic acids research, 49(13) 7298-7317, Jul 21, 2021

Misc.

Phosphorylation Profiling of Molecular-Targeting Drug-Treated Cancer Cells by High Performance Phosphoproteomics

ISHIHAMA Yasushi, ISHIHAMA Yasushi, SUGIYAMA Naoyuki, SUGIYAMA Naoyuki, KYONO Yutaka, KYONO Yutaka, IMAMI Koshi, MASUDA Takeshi, TOMITA Masaru, TOMITA Masaru

日本プロテオーム学会大会プログラム・抄録集, 2008 (Web), 2008

Major Research Projects

タンパク質翻訳機構のプロテオームレベルでの再考

JST創発的研究支援事業, 科学技術振興機構, Apr, 2022 - Mar, 2029

今見考志
Systematic analysis of protein N-terminal codes

Grants-in-Aid for Scientific Research Grant-in-Aid for Transformative Research Areas (A), Grant-in-Aid for Transformative Research Areas (A), Japan Society for the Promotion of Science, Sep, 2021 - Mar, 2023
共翻訳修飾の大規模計測技術の開発

科学研究費補助金基盤研究(B), 日本学術振興会, Apr, 2020 - Mar, 2023

今見考志
Development of exo-proteomics technologies to monitor the dynamics and cellular response of exosomes

PRESTO, JST, Oct, 2018 - Mar, 2022

Koshi Imami
摂動による迅速な翻訳応答を捉えるプロテオームリボソームプロファイリング法の開発

科学研究費補助金新学術領域研究（研究領域提案型）, 日本学術振興会, Apr, 2020 - Mar, 2021

今見考志
ミトリボソームインタラクトーム解析法の開発と生合成・翻訳制御因子の同定

科学研究費補助金若手研究, 日本学術振興会, Apr, 2018 - Mar, 2020

今見考志

Other

Paternity leave

Oct, 2017 - Nov, 2017
Paternity leave

Oct, 2013 - Dec, 2013

Profile Information

Research Interests

Research Areas

Research History

Education

Committee Memberships

Major Awards

Papers

Misc.

Major Research Projects

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