論文

国際誌
2020年11月17日

Cholecystitis after Placement of Covered Self-Expandable Metallic Stents in Patients with Distal Malignant Biliary Obstructions.

Clinical endoscopy
  • Masafumi Watanabe
  • ,
  • Kosuke Okuwaki
  • ,
  • Jun Woo
  • ,
  • Mitsuhiro Kida
  • ,
  • Hiroshi Imaizumi
  • ,
  • Tomohisa Iwai
  • ,
  • Hiroshi Yamauchi
  • ,
  • Toru Kaneko
  • ,
  • Rikiya Hasegawa
  • ,
  • Takahiro Kurosu
  • ,
  • Naoki Minato
  • ,
  • Hiroki Haradome
  • ,
  • Wasaburo Koizumi

記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.5946/ce.2020.136

Background/Aims: Cholecystitis can occur after the placement of covered self-expandable metallic stents for distal malignant biliary obstructions. We aimed to identify risk factors for cholecystitis following covered self-expandable metallic stent placement. Methods: We investigated risk factors related to cholecystitis following covered self-expandable metallic stent placement in 118 patients with distal malignant biliary obstructions between January 1, 2015 and April 30, 2019. Endoscopic assessments and tumor invasion to the arteries feeding the gallbladder were determined by a pancreaticobiliary endoscopist and a radiologist, respectively. Results: The median patient age was 72 years (men, 61.0%). The flow of the contrast agent into the gallbladder and tumor involvement in the orifice of the cystic duct were observed in 35 (29.7%) and 35 (29.7%) patients, respectively. During the observation period (median, 179 days), cholecystitis occurred in 18 (15.3%) patients. Multivariate analysis revealed the flow of the contrast agent into the gallbladder (p=0.023) and tumor involvement in the orifice of the cystic duct (p=0.005) as significant independent risk factors associated with cholecystitis. Conclusions: The flow of the contrast agent into the gallbladder and tumor involvement in the orifice of the cystic duct are potential independent risk factors for cholecystitis following the placement of covered self-expandable metallic stents. A follow-up prospective study is warranted to validate their influence.

リンク情報
DOI
https://doi.org/10.5946/ce.2020.136
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/33198440

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