2007年
Antibacterial activity and characteristics of modified ferrite powder coated with a gemini pyridinium salt molecule
Biocontrol Science
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- 巻
- 12
- 号
- 3
- 開始ページ
- 83
- 終了ページ
- 91
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.4265/bio.12.83
- 出版者・発行元
- Society for Antibacterial and Antifungal Agents Japan
This report describes the synthesis of an antibacterial material consisting of a gemini quaternary ammonium salt (gemini-QUAT) immobilized on ferrite powder, and its antibacterial activity. A gemini-QUAT containing two pyridinium residues per molecule, 4,4′-[1,3-(2,2-dihydroxylmethyl-1,3-dithiapropane)] bis (1-octylpyridinium bromide), was immobilized on ferrite powder by a reaction between the hydroxyl group of the QUAT and trimethoxysilane. Immobilization of the gemini-QUAT on ferrite (F-gemini-QUAT) was confirmed when the dye, bromophenol blue, was released from F-gemini-QUAT-dye after contact between ferrite and the dye. Elemental analysis of the QUAT-ferrite determined the molar amount of QUAT on the ferrite. The antibacterial effect of the ferrite was investigated using a batch treatment system, and this effect was compared with that of another QUAT-ferrite (F-mono-QUAT) binding a mono-QUAT, which possesses one pyridinium residue, prepared by the same immobilization method as F-gemini-QUAT. Results indicated the F-gemini QUAT possessed a higher bactericidal potency and broader antibacterial spectrum compared to F-mono-QUAT. In addition, this study suggested that gemini-QUATs possessed high bactericidal potency without being influenced by immobilization to materials, and the antibacterial activity and characteristics of F-gemini-QUAT could be attributed to the unique structure of the immobilized gemini-QUAT.
- リンク情報
- ID情報
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- DOI : 10.4265/bio.12.83
- ISSN : 1342-4815
- CiNii Articles ID : 10019858615
- PubMed ID : 17927048
- SCOPUS ID : 34548775026