Toshihide Kurihara

J-GLOBAL         Last updated: Jan 10, 2020 at 18:47
 
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Name
Toshihide Kurihara
Affiliation
Keio University
Section
School of Medicine
Job title
Associate Professor
Degree
MD(University of Tsukuba), PhD(Keio University)
Other affiliation
The Scripps Research Institute

Profile

Toshihide Kurihara is an Associate Professor of Ophthalmology and a Principal Investigator for the Laboratory of Photobiologyat at Keio University, Tokyo, Japan. He received his M.D. degree from the Faculty of Medicine, University of Tsukuba, Ibaraki, Japan, in 2001. He completed his ophthalmology residency at Keio University Hospital in 2005, and obtained his Ph.D. degree under the supervision of Professor Kazuo Tsubota from Keio University Graduate School of Medicine in 2009. Dr. Kurihara did his postdoctoral training under the mentorship of Professor Martin Friedlander at the Scripps Research Institute in La Jolla, California, USA. His research interest is hypoxia responses in development, physiology, and pathophysiology of the retina. Currently, he also conducts research focusing on visual restoration utilizing optogenetics technology and molecular mechanism of myopia development and progression.

Editorial Board Member: BioMed Research International, Journal of Ophthalmology, and Case Reports in Ophthalmological Medicine

Research Areas

 
 

Academic & Professional Experience

 
Apr 2017
 - 
Today
Project Associate Professor, School of Medicine, Keio University
 
Apr 2015
 - 
Mar 2017
Project Assistant Professor, Keio University School of Medicine
 
Apr 2015
 - 
Today
Principal Investigator, Keio University, Center for Integrated Medical Research
 
Jul 2013
 - 
Jun 2014
Adjunct Assistant Professor, The Scripps Research Institute
 
Jul 2013
 - 
Mar 2015
Assistant Professor, Keio University School of Medicine
 
Apr 2012
 - 
Jun 2013
Adjunct Assistant Professor, Keio University School of Medicine
 
Dec 2009
 - 
Jun 2013
Research Associate, The Scripps Research Institute
 
Jul 2009
 - 
Nov 2009
Postdoctral fellow, University of California San Diego
 
Apr 2009
 - 
Mar 2012
Lecturer, Keio University School of Medicine
 
Apr 2005
 - 
Mar 2009
Research Asistant, Keio University School of Medicine
 

Education

 
Apr 2005
 - 
Mar 2009
Graduate School of Medicine, Keio University
 
Apr 1995
 - 
Mar 2001
School of Medicine, University of Tsukuba
 

Awards & Honors

 
Jun 2016
Roles of hypoxia response in the retinal development and pathophysiology, Kitasato Award, Keio University School of Medicine
 
85th Kitasato Memorial Ceremony
Dec 2015
The 8th Tano Young Investigator's Award, Japanese Retina and Vitreous Society
 
Sep 2015
An association of serum vitamin D level with myopia initiation by UV exposure in chick, IMC International Travel Grant, International Myopia Conference
 
The 15th International Myopia Conference (IMC)
Jun 2015
Physiological function of vascular endothelial growth factor (VEGF) in the retina, Sanshikai Young Investigator Award, Keio University School of Medicine Alumni Association (Sanshikai)
 
May 2014
Neuronal VHL Deletion Induces Strong Suppression of Retinal Vascular Formation, ARVO/Alcon Early Career Clinician-Scientist Research Award, ARVO/Alcon Foundation
 
ARVO Annual Meeting 2014
Oct 2012
Age-related macular degeneration (AMD) induced by dysregulation of protein degradation and energy homeostasis via VHL-HIF axis, Future of Science Fund Scholarship, Keystone Symposia
 
Keystone Symposia Aging and Diseases of Aging 2012
Sep 2012
CRL2-VHL E3 ligase complex and age-related macular degeneration, 2nd Place Oral Presentation in Cell & Molecular Biology, Society of Fellows (SoF)
 
TSRI SoF Research Symposium 2012
Jul 2012
The role of von Hippel-Lindau tumor suppressor (VHL)-hypoxia-inducible factor (HIF) system in age-related macular degeneration, Young Investigator Travel Award, Fritz Tobler Foundation
 
XV International Symposium on Retinal Degeneration RD2012
Oct 2010
von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina, The 6th Young Investigator's Award 2010 of Alumni association of Keio University Department of Ophthalmology, Alumni association of Keio University Department of Ophthalmology
 
Annual meeting of Alumni association of Keio University Department of Ophthalmology 2010
Mar 2009
Physiological downregulation of HIF-1alpha is required for proper retinal vascular formation, Young Investigator's Award 2009 for Regenerative Medicine, Japanese Society for Regenerative Medicine
 
The 8th Congress of Japanese Society for Regenerative Medicine

Published Papers

 
Suzuki M, Nagai N, Minami S, Kurihara T, Kamoshita M, Sonobe H, Watanabe K, Shinoda H, Tsubota K, Ozawa Y†
Graefe's Archive for Clinical and Experimental Ophthalmology   258(1) 49-56   Jan 2020   [Refereed]
Mori K, Kurihara T†, Jiang X, Ikeda SI, Yotsukura E, Torii H, Tsubota K†
Nutrients   12(1) 180   Jan 2020   [Refereed]
Minami S, Shinoda H, Shigeno Y, Nagai N, Kurihara T, Watanabe K, Sonobe H, Takagi H, Tsubota K, Ozawa Y†
Scientific Reports   9(1) 19056   Dec 2019   [Refereed]
Minami S, Nagai N, Suzuki M, Kurihara T, Sonobe H, Watanabe K, Shinoda H, Takagi H, Tsubota K, Ozawa Y†
Scientific Reports   9(1) 18119   Dec 2019   [Refereed]
Mori K, Kurihara T†, Jiang X, Ikeda SI, Ishida A, Torii H, Tsubota K†
International Journal of Molecular Sciences   20(23) 6014   Nov 2019   [Refereed]
Tomita Y*, Ozawa N*, Miwa Y, Ishida A, Ohta M, Tsubota K†, Kurihara T†
International Journal of Molecular Sciences   20(23) 5878   Nov 2019   [Refereed]
Miwa Y, Tsubota K†, Kurihara T†
Molecular Vision   25 645-653   Oct 2019   [Refereed]
Mori K, Kurihara T†, Uchino M, Torii H, Kawashima M, Sasaki M, Ozawa Y, Yamagishi K†, Iso H, Sawada N, Tsugane S, Yuki K, Tsubota K
Journal of Clinical Medicine   8(11) 1788   Oct 2019   [Refereed]
Ibuki M, Shoda C, Miwa Y, Ishida A, Tsubota K†, Kurihara T†
International Journal of Molecular Sciences   20(20) 5049   Oct 2019   [Refereed]
Kunimi H, Miwa Y, Katada Y, Tsubota K†, Kurihara T†
PeerJ   7 e7849   Oct 2019   [Refereed]

Misc

 
Toshihide Kurihara
Retina Medicine   4(2) 160-164   Oct 2015   [Invited]
Toshihide Kurihara
Ganka-Ophthalmology   57(8) 1027-1036   Jul 2015
Toshihide Kurihara
Ganka-Ophthalmology   57(2) 127-132   Feb 2015   [Invited]
Toshihide Kurihara
Ganka -Ophthalmology-   55(7) 787-793   Jul 2013   [Invited]
The Scripps Research Institute
News & Views   12(34)    Oct 2012   [Invited]
Toshihide Kurihara
The JSPS San Francisco Newsletter   (25)    Mar 2012   [Invited]
栗原 俊英, 石田 晋
Anti-aging medicine   3(4) 426-430   Nov 2007
KURIHARA Toshihide, NODA Kousuke, NODA Mika, NAGAI Norihiro, INOUE Makoto
眼科手術 = Journal of ophthalmic surgery   20(3) 379-381   Jul 2007

Conference Activities & Talks

 
Proportion of light that reaches the mannequin's eye with or without eyeglass lenses under the sunshine
Shinichiro Kondo, Xiaoyan Jiang, Naoki Otsuka, Daisuke Kaneda, Hidemasa Torii, Toshihide Kurihara, Kazuo Tsubota
The 17th International Myopia Conference   14 Sep 2019   
The axial length changes by violet light exposure: 2-year outcome of two individual cases in a prospective clinical study
Hidemasa Torii, Toshihide Kurihara, Shinichiro Kondo, Erisa Yotsukura, Kiwako Mori, Hidenaga Kobashi, Xiaoyan Jiang, Shin-ichi Ikeda, Ikuko Toda, Kazuo Tsubota
The 17th International Myopia Conference   14 Sep 2019   
A multicenter double-blinded randomized trial of oral crocetin for myopia progression in children
Kiwako Mori, Hidemasa Torii, Satoko Fujimoto, Xiaoyan Jiang, Shin-ichi Ikeda, Erisa Yotsukura, Shizuka Koh, Toshihide Kurihara, Kohji Nishida, Kazuo Tsubota
The 17th International Myopia Conference   14 Sep 2019   
Molecular pathways of the violet light effect on myopia progression
Yumi Hagiwara, Toshihide Kurihara, Hidemasa Torii, Xiaoyan Jiang, Yasuhisa Tanaka, Masatsugu Nakamura, Kazuo Tsubota
The 17th International Myopia Conference   13 Sep 2019   
Amlexanox activating EGR-1 suppresses myopia progression in a murine model of lens-induced myopia
Yasuhisa Tanaka, Toshihide Kurihara, Xiaoyan Jiang, Kiwako Mori, Shin-ichi Ikeda, Yumi Hagiwara, Koushi Fujisawa, Masatomo Kato, Masatsugu Nakamura, Kazuo Tsubota
The 17th International Myopia Conference   13 Sep 2019   
Retinal ERK activation is involved with myopia progression in mice
Toshihide Kurihara, Yangsong Wang, Xiaoyan Jiang, Kiwako Mori, Hidemasa Torii, Shin-ichi Ikeda, Kazuo Tsubota
The 17th International Myopia Conference   13 Sep 2019   
Violet wavelength specificity for suppression of myopia in a murine LIM model
Xiaoyan Jiang, Toshihide Kurihara, Kiwako Mori, Shin-ichi Ikeda, Hidemasa Torii, Kazuo Tsubota
The 17th International Myopia Conference   13 Sep 2019   
Gut microbiota affects myopia progression in a murine lens-induced myopia model
Shin-ichi Ikeda, Toshihide Kurihara, Xiaoyan Jiang, Masataro Toda, Kiwako Mori, Hidemasa Torii, Kazuo Tsubota
The 17th International Myopia Conference   13 Sep 2019   
Violet light hypothesis for prevention of myopia
Kazuo Tsubota, Hidemasa Torii, Xiaoyan Jiang, Kiwako Mori, Yumi Tanaka, Yashihisa Tanaka, Shinichiro Kondo, Shin-ichi Ikeda, Toshihide Kurihara
The 17th International Myopia Conference   12 Sep 2019   
Myopia crisis among school children in Tokyo
Erisa Yotsukura, Hidemasa Torii, Mikako Inokuchi, Mitsuaki Tokumura, Miki Uchino, Kiwako Mori, Xiaoyan Jiang, Shin-ichi Ikeda, Shinichiro Kondo, Kazuno Negishi, Toshihide Kurihara, Kazuo Tsubota
The 17th International Myopia Conference   12 Sep 2019   

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research (基盤研究(C)) ¥4,810,000-
Project Year: Apr 2015 - Mar 2018    Investigator(s): Toshihide Kurihara
Charitable Trust Fund for Ophthalmic Research in Commemoration of Santen Pharmaceutical’s Founder: Grant-in-aid for Scientific Research ¥2,000,000-
Project Year: 2015 - 2016    Investigator(s): Toshihide Kurihara
Visual Regeneration by Optogenetics
Takeda Science Foundation: Visionary Research in Medical Field ¥2,000,000-
Project Year: 2013 - 2015    Investigator(s): Toshihide Kurihara
Uehara Memorial Foundation: Grants-in-Aid for Scientific Research ¥2,000,000-
Project Year: 2013 - 2015    Investigator(s): Toshihide Kurihara
Japan Society for the Promotion of Science (JSPS): Postdoctral Fellowship for Research Abroad
Project Year: Jul 2011 - Jun 2013    Investigator(s): Toshihide Kurihara
The role of HIF in diabetic retinopathy
Kowa Life Science Foundation: Grant-in-aid for international exchange
Project Year: Jul 2009 - Jun 2011    Investigator(s): Toshihide Kurihara
The role of hypoxia-inducible factors (HIF) in diabetic retinopathy
Manpei Suzuki Diabetes Foundation: Postdoctoral fellowship for research abroad 2009
Project Year: Jul 2009 - Jun 2011    Investigator(s): Toshihide Kurihara
Involvement of a transcriptional factor HIF-1 in corneal transparency
Japan Eye Bank Association: Grant-in-Aid for Scientific Research Abroad
Project Year: Jul 2009 - Jun 2010    Investigator(s): Toshihide Kurihara
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research (若手研究(B))
Project Year: 2009 - 2010    Investigator(s): Toshihide Kurihara
Alumni Association of Keio University Department of Ophthalmology: Grant-in-Aid for Research Abroad
Project Year: 2010       Investigator(s): Toshihide Kurihara