Toshihide Kurihara

J-GLOBAL         Last updated: Mar 13, 2019 at 19:09
 
Avatar
Name
Toshihide Kurihara
Affiliation
Keio University
Section
School of Medicine
Job title
Associate Professor
Degree
MD(University of Tsukuba), PhD(Keio University)
Other affiliation
The Scripps Research Institute

Profile

Toshihide Kurihara is an Associate Professor of Ophthalmology and a Principal Investigator for the Laboratory of Photobiologyat at Keio University, Tokyo, Japan. He received his M.D. degree from the Faculty of Medicine, University of Tsukuba, Ibaraki, Japan, in 2001. He completed his ophthalmology residency at Keio University Hospital in 2005, and obtained his Ph.D. degree under the supervision of Professor Kazuo Tsubota from Keio University Graduate School of Medicine in 2009. Dr. Kurihara did his postdoctoral training under the mentorship of Professor Martin Friedlander at the Scripps Research Institute in La Jolla, California, USA. His research interest is hypoxia responses in development, physiology, and pathophysiology of the retina. Currently, he also conducts research focusing on visual restoration utilizing optogenetics technology and molecular mechanism of myopia development and progression.

Editorial Board Member: BioMed Research International, Journal of Ophthalmology, and Case Reports in Ophthalmological Medicine

Research Areas

 
 

Academic & Professional Experience

 
Apr 2017
 - 
Today
Project Associate Professor, School of Medicine, Keio University
 
Apr 2015
 - 
Mar 2017
Project Assistant Professor, Keio University School of Medicine
 
Apr 2015
 - 
Today
Principal Investigator, Keio University, Center for Integrated Medical Research
 
Jul 2013
 - 
Jun 2014
Adjunct Assistant Professor, The Scripps Research Institute
 
Jul 2013
 - 
Mar 2015
Assistant Professor, Keio University School of Medicine
 
Apr 2012
 - 
Jun 2013
Adjunct Assistant Professor, Keio University School of Medicine
 
Dec 2009
 - 
Jun 2013
Research Associate, The Scripps Research Institute
 
Jul 2009
 - 
Nov 2009
Postdoctral fellow, University of California San Diego
 
Apr 2009
 - 
Mar 2012
Lecturer, Keio University School of Medicine
 
Apr 2005
 - 
Mar 2009
Research Asistant, Keio University School of Medicine
 

Education

 
Apr 2005
 - 
Mar 2009
Graduate School of Medicine, Keio University
 
Apr 1995
 - 
Mar 2001
School of Medicine, University of Tsukuba
 

Awards & Honors

 
Jun 2016
Roles of hypoxia response in the retinal development and pathophysiology, Kitasato Award, Keio University School of Medicine
 
85th Kitasato Memorial Ceremony
Dec 2015
The 8th Tano Young Investigator's Award, Japanese Retina and Vitreous Society
 
Sep 2015
An association of serum vitamin D level with myopia initiation by UV exposure in chick, IMC International Travel Grant, International Myopia Conference
 
The 15th International Myopia Conference (IMC)
Jun 2015
Physiological function of vascular endothelial growth factor (VEGF) in the retina, Sanshikai Young Investigator Award, Keio University School of Medicine Alumni Association (Sanshikai)
 
May 2014
Neuronal VHL Deletion Induces Strong Suppression of Retinal Vascular Formation, ARVO/Alcon Early Career Clinician-Scientist Research Award, ARVO/Alcon Foundation
 
ARVO Annual Meeting 2014
Oct 2012
Age-related macular degeneration (AMD) induced by dysregulation of protein degradation and energy homeostasis via VHL-HIF axis, Future of Science Fund Scholarship, Keystone Symposia
 
Keystone Symposia Aging and Diseases of Aging 2012
Sep 2012
CRL2-VHL E3 ligase complex and age-related macular degeneration, 2nd Place Oral Presentation in Cell & Molecular Biology, Society of Fellows (SoF)
 
TSRI SoF Research Symposium 2012
Jul 2012
The role of von Hippel-Lindau tumor suppressor (VHL)-hypoxia-inducible factor (HIF) system in age-related macular degeneration, Young Investigator Travel Award, Fritz Tobler Foundation
 
XV International Symposium on Retinal Degeneration RD2012
Oct 2010
von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina, The 6th Young Investigator's Award 2010 of Alumni association of Keio University Department of Ophthalmology, Alumni association of Keio University Department of Ophthalmology
 
Annual meeting of Alumni association of Keio University Department of Ophthalmology 2010
Mar 2009
Physiological downregulation of HIF-1alpha is required for proper retinal vascular formation, Young Investigator's Award 2009 for Regenerative Medicine, Japanese Society for Regenerative Medicine
 
The 8th Congress of Japanese Society for Regenerative Medicine

Published Papers

 
Miwa Y, Hoshino Y, Shoda C, Jiang X, Tsubota K, Kurihara T
Neurochemistry International      Mar 2019   [Refereed]
Jiang X, Kurihara T, Ikeda SI, Kunimi H, Mori K, Torii H, Tsubota K
Journal of Visualized Experiments   (143) e58822   Jan 2019   [Refereed]
Mori K, Kurihara T, Miyauchi M, Ishida A, Jiang X, Ikeda SI, Torii H, Tsubota K
Scientific Reports   9 295   Jan 2019   [Refereed]
Katada Y, Kobayashi K, Tsubota K, Kurihara T
PeerJ   7 e6317   Jan 2019   [Refereed]
Morita Y, Miwa Y, Jounai K, Fujiwara D, Kurihara T, Kanauchi O
Nutrients   10(12) pii: E1991   Dec 2018   [Refereed]
Jiang X, Kurihara T, Torii H, Tsubota K
Eye & Contact Lens   44(5) 273-278   Sep 2018   [Refereed]
Jiang X, Kurihara T, Kunimi H, Miyauchi M, Ikeda SI, Mori K, Tsubota K, Torii H, Tsubota K
Scientific Reports   8(1) 2026   Feb 2018   [Refereed]
Minami S, Nagai N, Suzuki M, Kurihara T, Sonobe H, Kamoshita M, Uchida A, Shinoda H, Takagi H, Sonoda S, Sakamoto T, Tsubota K, Ozawa Y
Scientific Reports   8(1) 58   Jan 2018   [Refereed]
Aketa N, Yamaguchi T, Asato T, Yagi-Yaguchi Y, Suzuki T, Higa K, Kurihara T, Satake Y, Tsubota K, Shimazaki J
American Journal of Ophthalmology   184 42-51   Dec 2017   [Refereed]
Torii H, Ohnuma K, Kurihara T, Tsubota K, Negishi K
Scientific Reports   7(1) 14523   Nov 2017   [Refereed]

Misc

 
Toshihide Kurihara
Retina Medicine   4(2) 160-164   Oct 2015   [Invited]
Toshihide Kurihara
Ganka-Ophthalmology   57(8) 1027-1036   Jul 2015
Toshihide Kurihara
Ganka-Ophthalmology   57(2) 127-132   Feb 2015   [Invited]
Toshihide Kurihara
Ganka -Ophthalmology-   55(7) 787-793   Jul 2013   [Invited]
The Scripps Research Institute
News & Views   12(34)    Oct 2012   [Invited]
Toshihide Kurihara
The JSPS San Francisco Newsletter   (25)    Mar 2012   [Invited]
栗原 俊英, 石田 晋
Anti-aging medicine   3(4) 426-430   Nov 2007
KURIHARA Toshihide, NODA Kousuke, NODA Mika, NAGAI Norihiro, INOUE Makoto
眼科手術 = Journal of ophthalmic surgery   20(3) 379-381   Jul 2007

Conference Activities & Talks

 
Genotype Phenotype Association in East Asian Patients with Occult Macular Dystrophy (Miyake’s disease); EAOMD Report No.4
Yu (Yokokawa) Fujinami, Lizhu Yang, Kwangsic Joo, Kazushige Tsunoda, Mineo Kondo, Gavin Arno, Xiao Liu, Toshihide Kurihara, Kazuo Tsubota, Xuan Zou, Hui Li, Kyu Hyung Park, Yozo Miyake, Takeshi Iwata, Se Joon Woo, Ruifang Sui, Kaoru Fujinami
56th ISCEV Symposium   20 Jun 2018   
Distribution of generalized functional phenotype of East Asian Patients with Stargardt Disease (STGD1): EAStar studies report 2
Xiao Liu, Lizhu Yang, Kwangsic Joo, Kazushige Tsunoda, Takaaki Hayashi, Kei Shinoda, Atsushi Mizota, Mineo Kondo, Kazuki Kuniyoshi, Yu (Yokokawa) Fujinami, Gavin Arno, Toshihide Kurihara, Kazuo Tsubota, Yozo Miyake, Ya Li, Kyu Hyung Park, Dae Joong Ma, Hyeong Gon Yu, Bo Lei, Takeshi Iwata, Se Joon Woo, Shiying Li, Kaoru Fujinami
56th ISCEV Symposium   20 Jun 2018   
Multimodal imaging of East Asian Patients with Occult Macular Dystrophy (Miyake’s disease): EAOMD Report No. 3
Kwangsic Joo, Lizhu Yang, Kazushige Tsunoda, Mineo Kondo, Yu Fujinami, Gavin Arno, Toshihide Kurihara, Kazuo Tsubota, Takeshi Iwata, Xuan Zou, Hui Li, Yozo Miyake, Kyu Hyung Park, Kaoru Fujinami, Ruifang Sui, Se Joon Woo
ARVO 2018 Annual Meeting   30 Apr 2018   
Pemafibrate prevents retinal pathological neovascularization via systemic metabolic cascades in mice
Yohei Tomita, Yukihiro Miwa, maki miyauchi, Ayako Ishida, Hiromitsu Kunimi, Yusaku katada, Kazuo Tsubota, Toshihide Kurihara
ARVO 2018 Annual Meeting   1 May 2018   
The relationship between violet light transmittance of contact lenses and axial length elongation
Hidemasa Torii, Toshihide Kurihara, Shinichiro Kondo, Xiaoyan Jiang, Kiwako Mori, Shin-cihi Ikeda, Erisa Yotsukura, Keiichi Kato, Kazuno Negishi, Kazuo Tsubota
ARVO 2018 Annual Meeting   30 Apr 2018   
Clinical and Genetic Characteristics of East Asian Patients with Occult Macular Dystrophy (Miyake’s disease); EAOMD Report No.1
Kaoru Fujinami, Lizhu Yang, Kwangsic Joo, Kazushige Tsunoda, Yuichi Kawamura, Yu Fujinami, Gavin Arno, Toshihide Kurihara, Kazuo Tsubota, Xuan Zou, Hui Li, Kyu Hyung Park, Takeshi Iwata, Yozo Miyake, Se Joon Woo, Ruifang Sui
ARVO 2018 Annual Meeting   30 Apr 2018   
Predictive factors for better short-term outcome in idiopathic epiretinal membrane after pars plana vitrectomy
Sakiko Minami, Yuta Shigeno, Hajime Shinoda, Norihiro Nagai, Toshihide Kurihara, Mamoru Kamoshita, Kazuhiro Watanabe, Hideki Sonobe, Yuki Hidaka, Kazuo Tsubota, Yoko Ozawa
ARVO 2018 Annual Meeting   29 Apr 2018   
Violet light exposure suppresses refractive change and axial elongation in a murine model of lens-induced myopia
Toshihide Kurihara, Xiaoyan Jiang, Kiwako Mori, Shin-cihi Ikeda, Hidemasa Torii, Kazuo Tsubota
ARVO 2018 Annual Meeting   29 Apr 2018   
A comparison of form deprivation myopia with lens-induced myopia using newly designed eyeglasses for mice.
Xiaoyan Jiang, Toshihide Kurihara, Maki Miyauchi, Shin-ichi Ikeda, Kiwako Mori, Kinya Tsubota, Hidemasa Torii, Kazuo Tsubota
The 16th International Myopia Conference   16 Sep 2017   
Comparison of violet light spectra and irradiance between outdoor and indoor environments.
Shinichiro Kondo, Toshihide Kurihara, Hidemasa Torii, Xiaoyan Jiang, Kiwako Mori, Kazuo Tsubota
The 16th International Myopia Conference   16 Sep 2017   

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research (基盤研究(C)) ¥4,810,000-
Project Year: Apr 2015 - Mar 2018    Investigator(s): Toshihide Kurihara
Charitable Trust Fund for Ophthalmic Research in Commemoration of Santen Pharmaceutical’s Founder: Grant-in-aid for Scientific Research ¥2,000,000-
Project Year: 2015 - 2016    Investigator(s): Toshihide Kurihara
Visual Regeneration by Optogenetics
Takeda Science Foundation: Visionary Research in Medical Field ¥2,000,000-
Project Year: 2013 - 2015    Investigator(s): Toshihide Kurihara
Uehara Memorial Foundation: Grants-in-Aid for Scientific Research ¥2,000,000-
Project Year: 2013 - 2015    Investigator(s): Toshihide Kurihara
Japan Society for the Promotion of Science (JSPS): Postdoctral Fellowship for Research Abroad
Project Year: Jul 2011 - Jun 2013    Investigator(s): Toshihide Kurihara
The role of HIF in diabetic retinopathy
Kowa Life Science Foundation: Grant-in-aid for international exchange
Project Year: Jul 2009 - Jun 2011    Investigator(s): Toshihide Kurihara
The role of hypoxia-inducible factors (HIF) in diabetic retinopathy
Manpei Suzuki Diabetes Foundation: Postdoctoral fellowship for research abroad 2009
Project Year: Jul 2009 - Jun 2011    Investigator(s): Toshihide Kurihara
Involvement of a transcriptional factor HIF-1 in corneal transparency
Japan Eye Bank Association: Grant-in-Aid for Scientific Research Abroad
Project Year: Jul 2009 - Jun 2010    Investigator(s): Toshihide Kurihara
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research (若手研究(B))
Project Year: 2009 - 2010    Investigator(s): Toshihide Kurihara
Alumni Association of Keio University Department of Ophthalmology: Grant-in-Aid for Research Abroad
Project Year: 2010       Investigator(s): Toshihide Kurihara