KUSE Masaki

Last updated: Oct 10, 2019 at 14:39

Name	KUSE Masaki
URL	http://www.research.kobe-u.ac.jp/ans-nprd-chem/contents/en/en_index.html
Affiliation	Kobe University
Section	Graduate School of Agricultural Science Department of Agrobioscience
Job title	Associate Professor
Degree	Master of Agriculture(Nagoya University), Doctor of Agriculture(Nagoya University)

Profile

b. Toyama
Toyama Chubu HS. (1991)
BSc. Nagoya Univ. (1995)
MSc. Nagoya Univ. (1997)
PhD. Nagoya Univ. (2000) (Prof. Minoru Isobe)
Res. Assist. Nagoya Univ (2000-2001)
Assist. Prof. Nagoya Univ. (2001-2011)
Assoc. Prof. Kobe Univ. (2011-) (Lab. Prof. Hirosato Takikawa)

Research Interests

bioluminescence(10) , Organic Synthesis(239) , Spectral measurement(1) , Chemical Biology(134)

Research Areas

Applied Chemistry / Synthetic chemistry /
Biomolecular science / Biomolecular science /
Chemistry / Organic chemistry /
Applied Chemistry / Bio-related chemistry /
Agricultural chemistry / Bioproduction chemistry/Bioorganic chemistry /

Education

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1995

Faculty of Agriculture, Nagoya University

2000

Nagoya University

Awards & Honors

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Dec 2016

高輝度発光基質による発光タンパク質フォラシンの再構成と発光活性, 日本農芸化学会　関西支部　支部賛助企業特別賞, 日本農芸化学会　関西支部

Winner: 大西　里佳, KUSE MASAKI, TAKIKAWA HIROSATO

Mar 2016

A concise synthesis of optically active solanacol, the germination stimulant for seeds of root parasitic weeds, BBB論文賞, 日本農芸化学会

Winner: Hiroshi Kumagai, Mami Fujiwara, Masaki Kuse, Hirosato Takikawa

Dec 2013

発行波長を改変する生物発光基質アナログの化学合成, 日本農芸化学会関西支部賛助企業特別賞, 日本農芸化学会関西支部

Winner: 松岡絢香, 南郷成子, 古市卓也, 久世雅樹, TAKIKAWA HIROSATO

Mar 2013

海洋生物由来の発光タンパク質に関する生物有機化学的研究, JSBBA Award for Young Scientists, 日本農芸化学会

Winner: Masaki KUSE

2000

光親和性標識と質量分析を用いた発光タンパクの活性中心に関する生物有機化学的研究, 財団法人サントリー生物有機科学研究所, 財団法人サントリー生物有機科学研究所

Winner: KUSE MASAKI

Published Papers

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Ethyl Acetate Fraction of Solanum nigrum L.: Cytotoxicity, Induction of Apoptosis, Cell Cycle in Breast Cancer Cells, and Gas Chromatography-Mass Spectrometry Analysis

Ehssan H. O. Moglad, Muddathir S. Alhassan, Eshtiyag A. Abdalkareem, Ashraf N. Abdalla, Masaki Kuse

Asian Journal of Pharmaceutics 13(3) 246-251 Sep 2019 [Refereed]

Enhanced elevations of hypo-osmotic shock-induced cytosolic and nucleic calcium concentrations in tobacco cells by pretreatment with dimethyl sulfoxide

Hieu T. H. Nguyen, François Bouteau, Christian Mazars, KUSE MASAKI, Tomonori Kawano

Bioscience, Biotechnology, and Biochemistry 83(2) 318-321 Feb 2019 [Refereed]

Natural Products Responsible for Bioluminescence: Synthesis of Coelenterazines and Dehydrocoelenterazines

MAIKO MORIGUCHI, SAYAKA IBA, KUSE MASAKI

Journal of Synthetic Organic Chemistry 76(10) 1000-1009 Oct 2018 [Refereed]

The involvement of calmodulin and protein kinases in the upstream of cytosolic and nucleic calcium signaling induced by hypoosmotic shock in tobacco cells

H. T. H. Nguyen, F. Bouteau, C. Mazars, KUSE MASAKI, T. Kawano

PLANT SIGNALING & BEHAVIOR e1494467 1-7 Aug 2018 [Refereed]

First synthesis of (S)-(+)-hymenoic acid, a DNA polymerase λ inhibitor isolated from Hymenochaetaceae sp

Kensuke Takahashi, Miki Matsui, KUSE MASAKI, TAKIKAWA HIROSATO

Bioscience, Biotechnology, and Biochemistry 82(1) 42-45 Dec 2017 [Refereed]

Total Synthesis of (±)-Ramariolides C and D

Masaki Kuse, Maiko Moriguchi, Masashi Hachida, Hirosato Takikawa

Chemistry Letters 46(9) 1409-1411 Sep 2017 [Refereed]

Ramariolides A–D (1–4) were isolated from the coral mushroom Ramaria cystidiophora, out of which 1 showed in vitro antimicrobial activity. The structural features of 1–4 are attractive synthetic targets. Here, we report the total synthesis of rama...

Identification of (Z)-3:(E)-2-hexenal isomerases essential to the production of the leaf aldehydes in plants

Mikiko Kunishima, Yasuo Yamauchi, Masaharu Mizutani, Masaki Kuse, Hirosato Takikawa, Yukihiro Sugimoto

J. Biol. Chem. 291 14023-14033 Jul 2016 [Refereed]

First synthesis of (±)-hostasolide A

Shun Yamamoto, Kuse Masaki, Hirosato Takikawa

Tetrahedron Lett. 56(42) 5808-5810 Sep 2015 [Refereed]

A concise synthesis of optically active solanacol, the germination stimulant for seeds of root parasitic weeds

Hiroshi Kumagai, Mami Fujiwara, Kuse Masaki, Hirosato Takikawa

Biosci. Biotechnol. Biochem. 79(8) 1240-1245 Aug 2015 [Refereed]

Chromophores in photoproteins of a glowing squid and mollusk

KUSE MASAKI

Bioscience, Biotechnology, and Biochemistry 78(5) 731-736 May 2014 [Refereed][Invited]

ヒカリカモメガイ由来の発光タンパク質（フォラシン）　小さな発見に至るまでの長い道のり

KUSE MASAKI

化学と生物 52(3) 166-171 Mar 2014 [Refereed][Invited]

Formal synthesis of soybean phytoalexin glyceollin I

Yuta Kohno, Masatsugu Koso, Masaki Kuse, Hirosato Takikawa

Tetrahedron Lett. 55(10) 1826-1828 Mar 2014 [Refereed]

First synthesis of decaturin C, an antiinsectant diterpenoid isolated from Penicillium thiersii

Nakazaki, K. ;Hayashi, K. ;Hosoe, S. ;Tashiro, T. ;Kuse, M. ;Takikawa, H.

Tetrahedron 68(44) 9029-9034 2012 [Refereed]

Dynamic chirality determines critical roles for bioluminescence in symplectin-dehydrocoelenterazine system.

Kongjinda V, Nakashima Y, Tani N, Kuse M, Nishikawa T, Yu CH, Harada N, Isobe M

Chemistry, an Asian journal 6(8) 2080-2091 Aug 2011 [Refereed]

Identification of a fluorescent compound in the cuticle of the train millipede Parafontaria laminata armigera.

Kuse M, Yanagi M, Tanaka E, Tani N, Nishikawa T

Bioscience, biotechnology, and biochemistry 74(11) 2307-2309 2010 [Refereed]

Identification of a Fluorescent Compound in the Cuticle of the Train Millipede Parafontaria laminata armigera

eiko tanaka, masaki kuse, miho yanagi, naoki tani, toshio nishikawa

Bioscience, Biotechnology, and Biochemistry 74 2307-2309 2010 [Refereed]

Dehydrocoelenterazine is the organic substance constituting the prosthetic group of Pholasin.

Tanaka E, Kuse M, Nishikawa T

Chembiochem : a European journal of chemical biology 10 2725-2729 Nov 2009 [Refereed]

Prevention of copper-induced calcium influx and cell death by prion-derived peptide in suspension-cultured tobacco cells.

Kagenishi T, Yokawa K, Kuse M, Isobe M, Bouteau F, Kawano T

Zeitschrift fur Naturforschung. C, Journal of biosciences 64 411-417 May 2009 [Refereed]

Selective protein modification by the hydroperoxide intermediate in a photoprotein, aequorin.

Doi I, Kuse M, Nishikawa T, Isobe M

Bioorganic & medicinal chemistry 17(9) 3399-3404 May 2009 [Refereed]

Substituent effect of imino-O-arenesulfonates, a coupling partner in Suzuki-Miyaura Reaction for substitution of the Pyrazine Ring: A Study for the Synthesis of Coelenterazine Analogs.

Arthit Makarasen, Masaki Kuse, Toshio Nishikawa, Minoru Isobe

Bull. Chem. Soc. Jpn 82(7) 870-878 2009

Differentiation of coelenteramide sulfate from phosphate by hydrogen/deuterium exchange coupled with ion trap mass spectrometry.

Issei DOI, Masaki KUSE, Yosuke NAKASHIMA, Naoki TANI, Minoru ISOBE

J. Mass Spectrom. Soc. Jpn. 57(2) 89-95 2009

1H NMR Aided Elucidation of Products Derived from Photodegradation of Ethyl 3-azido-4,6-difluorobenzoate in 2,2,2-Trifluoroethanol.

SYDNES Magne O., KUSE Masaki, DOI Issei, ISOBE Minoru

Tetrahedron 65(19) 3863-3870 2009 [Refereed]

Pholasin luminescence is enhanced by addition of dehydrocoelenterazine.

Kuse M, Tanaka E, Nishikawa T

Bioorganic & medicinal chemistry letters 18(20) 5657-5659 Oct 2008 [Refereed]

Protein phosphatase inhibitory activity of tautomycin photoaffinity probes evaluated at femto-molar level.

Sydnes MO, Kuse M, Kurono M, Shimomura A, Ohinata H, Takai A, Isobe M

Bioorganic & medicinal chemistry 16(4) 1747-1755 Feb 2008 [Refereed]

Determination of solvent-trapped products obtained by photolysis of aryl azides in 2,2,2-trifluoroethanol.

Sydnes MO, Doi I, Ohishi A, Kuse M, Isobe M

Chemistry, an Asian journal 3(1) 102-112 Jan 2008 [Refereed]

Chemistry for biology of symplectin bioluminescence with fluoro-dehydrocoelenterazine.

KUSE MASAKI

Chemiluminescence and Bioluminescence 51-54 2008 [Refereed]

Cysteine-390 is the binding site of luminous substance with symplectin, a photoprotein from Okinawan squid, Symplectoteuthis oualaniensis.

Isobe M, Kuse M, Tani N, Fujii T, Matsuda T

Proceedings of the Japan Academy. Series B, Physical and biological sciences 84(9) 386-392 2008 [Refereed]

Reductive monoalkylation of nitro aryls in one-pot

SYDNES Magne O., KUSE Masaki, ISOBE Minoru, ISOBE Minoru

Tetrahedron 64(27) 6406-6414 2008

Novel synthetic route of coelenterazines -2-: Synthesis of various dehydrocoelenterazine analogs

KONDO Nobuhiro, KUSE Masaki, MUTARAPAT Thumnoon, THASANA Nopporn, ISOBE Minoru

Heterocycles 65(4) 843-856 2005

Synthesis of Azide-Fluoro-Dehydrocoelenterazine analog as a Photoaffinity-Labeling Probe and Photolysis of Azide-Fluoro-Coelenterazine.

KUSE Masaki, DOI Issei, KONDO Nobuhiro, KAGEYAMA Yukari, ISOBE Minoru

Tetrahedron 61(24) 5754-5762 2005

Action of aluminum, novel TPC1-type channel inhibitor, against salicylate-induced and cold-shock-induced calcium influx in tobacco BY-2 cells.

LIN Cun, YU Yawei, KADONO Takashi, IWATA Michiaki, UMEMURA Kenji, FURUICHI Takuya, KUSE Masaki, ISOBE Minoru, YAMAMOTO Yoko, MATSUMOTO Hideaki, YOSHIZUKA Kazuharu, KAWANO Tomonori

Biochemical and Biophysical Research Communications 332(3) 823-830 2005

Studies on the bioluminescent mechanism of the symplectin photoprotein

KUSE MASAKI

Chemiluminescence and Bioluminescence 7-10 2005

Novel Synthetic Route of Aryl-Aminopyrazine

KUSE M, KONDO N, OHYABU Y, ISOBE M

Tetrahedron 60(4) 835-840 2004

Molecular diversity of cereulide detected by means of nano-HPLC-ESI-Q-TOF-MS

PITCHAYAWASIN S, ISOBE M, KUSE M, FRANZ T, AGATA N, OHTA M

International Journal of Mass Spectrometry 235(2) 123-129 2004

Aluminum as a specific inhibitor of plant TPC1 Ca2+ channels

KAWANO T, KADONO T, FUMOTO K, LAPEYRIE F, KUSE M, ISOBE M, FURUICHI T, MUTO S

Biochem. Biophys. Res. Commun. 324(1) 40-45 2004

Studies on the bioluminescent mechanism of the symplectin photoprotein

KUSE MASAKI

Luminescence 19 157-158 2004

Complexation of cyclic dodecadepsipeptide, Cereulide with ammonium salts

PITCHAYAWASIN S, KUSE M, KOGA K, ISOBE M, AGATA N, OHTA M

Bioorganic & Medicinal Chemistry Letters 13(20) 3507-3512 2003

19F-Dehydrocoelenterazine as Probe to Investigate the Active Site of Symplectin

ISOBE M, FUJII T, KUSE M, MIYAMOTO K, KOGA K

Tetrahedron 58(11) 2117-2126 2002

A novel 60 kDa-photoprotein from oceanic sqiud (symplectoteuthis oualaniensis) with sequence similarity to mammalian carbon-nitrogen hydrolase domains

FUJII T, AHN J‐Y, KUSE M, MORI H, MATSUDA T, ISOBE M

Biochem. Biophys. Research Communication 293(2) 874-879 2002

7,8-Dihydropterin-6-carboxylic acid as Light Emitter of Luminous Millipede, Luminodesmus sequoiae

KUSE M, KANAKUBO A, SUWAN S, KOGA K, ISOBE M, SHIMOMURA O

Bioorganic & Medicinal Chemistry Letters 11(8) 1037-1040 2001

Synthesis of 13C-Dehydrocoelenterazine and NMR Studies on the Bioluminescence of a Symplectoteuthis Model

KUSE M, ISOBE M

Tetrahedron 56(17) 2629-2639 2000

High Incorporation of L-Amino Acid to Cereulide, and Emetic Toxin from Bacillus cereus

Masaki Kuse, Thomas Franz, Kazushi Koga, Sathorn Suwan, Minoru Isobe, Norio Agata, Michio Ohta

Bioorganic & Medicinal Chemistry Letters 10(8) 735-739 2000 [Refereed]

Cremiluminescence and Bioluminescence, and its application

ISOBE MINORU, KUSE MASAKI

Farumashia 34(1) 20-24 Jan 1998

Synthesis of 13C-Dehydrocoelenterazine and Model Studies on Symplectoteuthis Squid Bioluminesecence

ISOBE M, KUSE M, YASUDA Y, TAKAHASHI H

Bioorganic & Medicinal Cremistry Letters 8(20) 2919-2924 1998

Chemistry of Photoproteins As Interface between Bioactive Molecules and Protein Function

ISOBE M, FUJII T, SUWAN S, KUSE M, TSUBOI K, MIYAZAKI A, FENG M C, LI J

Pure & Applied Chemistry 70(11) 2085-2092 1998

Synthesis and Proof of 1,2-Dioxetanone: Low-temperature Photooxygenation of Coelenterate Luciferin Analog

KUSE MASAKI

LANDMARKS IN PHOTOBIOLOGY 149-156 1998

Recent advances of chemistry of bioluminescence

ISOBE Minoru, FUJII Tatsuya, USAMI Ken, KUSE Masaki

Biochemistry 68(11) 1683-1691 Nov 1996

Misc

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23 Molecular Mechanism of Luminous Jellyfish Bioluminescence by means of Photolysis of Aequorin(Oral Presentation)

Doi Issei, Kuse Masaki, Nishikawa Toshio, Isobe Minoru

天然有機化合物討論会講演要旨集 (50) 161-166 Sep 2008

Our research has been focusing on the molecular mechanism of a luminous jellyfish, Aequorea aequorea. This jellyfish has a photoprotein (aequorin), which contains coelenterazine (CL) as a chromophore. The chromophore exists as an imidazopyrazinone...

17 Molecular Mechanisms of Bioluminescence of Symplectin. a Photoprotein from Okinawan Squid, Symplectoteuthis oualaniensis L.

Isobe Minoru, Kuse Masaki, Fujii Tatsuya, Takahashi Hiroyuki, Ohshima Kenji, Mori Hitoshi, Ahn J.-Y., Matsuda Tsukasa

天然有機化合物討論会講演要旨集 (42) 97-102 Oct 2000

We have been studying on a bioluminescence system of an oceanic luminous squid. Symplectoteuthis oualaniensis L. In 1981, Tsuji and Leisman reported that a homogenate of the luminous organ of this squid gave light in the presence of monocations su...

化学発光と生物発光及びその利用

ISOBE MINORU, KUSE MASAKI

Farumashia 34(1) 20-24 Jan 1998

Cremistry of Bioluminescence ; Recent Progress

Biochemistry 68(11) 1683 1996