Keizo Tokuhiro

J-GLOBAL         Last updated: Aug 17, 2019 at 10:30
Keizo Tokuhiro
Kansai Medical University
Institute of Biomedical Science
Research funding number

Research Areas


Academic & Professional Experience

Apr 2018
Specially-Appointed Associate Professor, Institute of Biomedical Science, Kansai Medical University
Jan 2017
Apr 2018
Research Fellow, National Institutes of Health
Jan 2012
Jan 2017
Visiting Fellow, National Institutes of Health
Apr 2008
Jan 2012
Postdoctoral Fellow, Research Institute for Microbial Diseases, Osaka University
Jul 2005
Mar 2008
Research Institute for Microbial Diseases, Osaka University


Apr 2003
Mar 2005
Graduate School of Science, Osaka City University
Apr 1999
Mar 2003
Department of Biology, Faculty of Science, Osaka City University

Awards & Honors

Apr 2019
The Young Scientists’ Prize, Ministry of Education, Culture, Sports, Science and Technology
Oct 2013
Molecular Investigations of the Polyspermy Block Mechanisms in mammals, Research Fellowship, The Kanae Foundation for the Promotion of Medical Science
Mar 2012
Molecular Investigations of the Polyspermy Block Mechanisms, Research Fellowship, The Uehara Memorial Foundation
Jul 2007
Functional Analysis of Meichroacidin (MCA) in Mouse Spermatogenesis, Chairman's Special Award of the 26th Japan Society of Andrology Annual Meeting, Japan Society of Andrology

Published Papers

Vogt EJ, Tokuhiro K, Guo M, Dale R, Yang G, Shin SW, Movilla MJ, Shroff H, Dean J.
Nature Communications   10(1) 2271   May 2019   [Refereed]
Tokuhiro K, Dean J.
Developmental cell   46(5) 627-640   Sep 2018   [Refereed]
Zhou L, Canagarajah B, Zhao Y, Baibakov B, Tokuhiro K, Maric D, Dean J
Developmental cell   40(5) 453-466   Mar 2017   [Refereed]
Tokuhiro K, Satouh Y, Nozawa K, Isotani A, Fujihara Y, Hirashima Y, Matsumura H, Takumi K, Miyano T, Okabe M, Benham AM, Ikawa M
Scientific reports   5 14254   Sep 2015   [Refereed]
Fujihara Y, Tokuhiro K, Muro Y, Kondoh G, Araki Y, Ikawa M, Okabe M
Proceedings of the National Academy of Sciences of the United States of America   110(20) 8111-8116   May 2013   [Refereed]


The Zona Pellucida Facilitates Fertilization, Blocks Polyspermy and Protects Pre-Implantation Embryos.
Keizo Tokuhiro, Jurrien Dean
Encyclopedia of Reproduction, Second Edition   3 294-299   Jul 2018

Conference Activities & Talks

Loss of the maternal-effect gene Mater delays exocytosis in mouse eggs
Vogt J. E., Tokuhiro K., Jimenez-Movilla M., Dean J.
Gordon research conference   16 Jul 2017   
ZP1 contributes to the prevention of polyspermy in mice
Banks N., Avella M., Baibakov B., Tokuhiro K., Dean J.
American Society for Reproductive Medicine 2016 Scientific Congress   15 Oct 2016   
Molecular investigations of the post-fertilization block to sperm penetration of the zona pellucida in mice
Tokuhiro K., Baibakov B., Dean J.
49th Annual Meeting of the Society for the Study of Reproduction   16 Jul 2016   
Nonmuscle myosin II‐A plays a role in sperm development
Lerma Cervantes C.B., Tokuhiro K., Billington N., Wang A., Conti M.A., Zhang Y., Kelley M.J., Daniels M.P., Sellers J.R., Dean J., Adelstein R.S.
2015 ASCB annual meeting   12 Dec 2015   
Neither N- nor O-glycans in the N-terminus of ZP2 are essential for fertility in mice
Tokuhiro K., Baibakov B., Dean J.
48th Annual Meeting of the Society for the Study of Reproduction   18 Jun 2015   

Association Memberships