Dohyun Im

Neurotransmitter recognition by human vesicular monoamine transporter 2.

Dohyun Im, Mika Jormakka, Narinobu Juge, Jun-Ichi Kishikawa, Takayuki Kato, Yukihiko Sugita, Takeshi Noda, Tomoko Uemura, Yuki Shiimura, Takaaki Miyaji …

Nature communications, 15(1) 7661-7661, Sep 16, 2024

Crystal structure reveals the binding mode and selectivity of a photoswitchable ligand for the adenosine A2A receptor.

Tsuyoshi Araya, Yuya Matsuba, Harufumi Suzuki, Tomohiro Doura, Nipawan Nuemket, Eriko Nango, Masaki Yamamoto, Dohyun Im, Hidetsugu Asada, Shigeki Kiyonaka …

Biochemical and biophysical research communications, 695 149393-149393, Feb 5, 2024 Peer-reviewed

Structural insights into the agonists binding and receptor selectivity of human histamine H4 receptor.

Dohyun Im, Jun-Ichi Kishikawa, Yuki Shiimura, Hiromi Hisano, Akane Ito, Yoko Fujita-Fujiharu, Yukihiko Sugita, Takeshi Noda, Takayuki Kato, Hidetsugu Asada …

Nature communications, 14(1) 6538-6538, Oct 20, 2023 Peer-reviewedLead author

Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography

Alexander M. Wolff, Eriko Nango, Iris D. Young, Aaron S. Brewster, Minoru Kubo, Takashi Nomura, Michihiro Sugahara, Shigeki Owada, Benjamin A. Barad, Kazutaka Ito …

Nature Chemistry, Sep 18, 2023 Peer-reviewed

Molecular basis for anti-insomnia drug design from structure of lemborexant-bound orexin 2 receptor.

Hidetsugu Asada, Dohyun Im, Yunhon Hotta, Satoshi Yasuda, Takeshi Murata, Ryoji Suno, So Iwata

Structure (London, England : 1993), 30(12) 1582-1589, Dec 1, 2022 Peer-reviewed

S1PR3-G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation.

Masayasu Toyomoto, Asuka Inoue, Kei Iida, Masatsugu Denawa, Isao Kii, Francois Marie Ngako Kadji, Takayuki Kishi, Dohyun Im, Tatsuro Shimamura, Hiroshi Onogi …

Cell chemical biology, 28(8) 1132-1144, Aug 19, 2021 Peer-reviewed

Structure of the dopamine D2 receptor in complex with the antipsychotic drug spiperone.

Dohyun Im, Asuka Inoue, Takaaki Fujiwara, Takanori Nakane, Yasuaki Yamanaka, Tomoko Uemura, Chihiro Mori, Yuki Shiimura, Kanako Terakado Kimura, Hidetsugu Asada …

Nature communications, 11(1) 6442-6442, Dec 22, 2020 Peer-reviewedLead author

The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone.

Hidetsugu Asada, Asuka Inoue, Francois Marie Ngako Kadji, Kunio Hirata, Yuki Shiimura, Dohyun Im, Tatsuro Shimamura, Norimichi Nomura, Hiroko Iwanari, Takao Hamakubo …

Structure (London, England : 1993), 28(4) 418-425, Apr 7, 2020 Peer-reviewed

Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals.

Alexander M Wolff, Iris D Young, Raymond G Sierra, Aaron S Brewster, Michael W Martynowycz, Eriko Nango, Michihiro Sugahara, Takanori Nakane, Kazutaka Ito, Andrew Aquila …

IUCrJ, 7(Pt 2) 306-323, Mar 1, 2020 Peer-reviewed

生理活性物質アンジオテンシンIIの結合によるアンジオテンシンII受容体活性化機構の構造基盤

浅田秀基, 井上飛鳥, Francois Kadji M.N., 平田邦生, 椎村祐樹, Dohyun Im, 青木淳賢, 岩田想

日本生化学会大会プログラム・講演要旨集, 92回 [1T03m-04], Sep, 2019

Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine.

Kanako Terakado Kimura, Hidetsugu Asada, Asuka Inoue, Francois Marie Ngako Kadji, Dohyun Im, Chihiro Mori, Takatoshi Arakawa, Kunio Hirata, Yayoi Nomura, Norimichi Nomura …

Nature structural & molecular biology, 26(2) 121-128, Feb, 2019 Peer-reviewed

Ligand complex structures of l-amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813 and its conformational change.

Dohyun Im, Daisuke Matsui, Takatoshi Arakawa, Kimiyasu Isobe, Yasuhisa Asano, Shinya Fushinobu

FEBS open bio, 8(3) 314-324, Mar, 2018 Peer-reviewedLead author

Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA.

Ryoji Suno, Kanako Terakado Kimura, Takanori Nakane, Keitaro Yamashita, Junmei Wang, Takaaki Fujiwara, Yasuaki Yamanaka, Dohyun Im, Shoichiro Horita, Hirokazu Tsujimoto …

Structure (London, England : 1993), 26(1) 7-19, Jan 2, 2018 Peer-reviewed

A three-dimensional movie of structural changes in bacteriorhodopsin.

Eriko Nango, Antoine Royant, Minoru Kubo, Takanori Nakane, Cecilia Wickstrand, Tetsunari Kimura, Tomoyuki Tanaka, Kensuke Tono, Changyong Song, Rie Tanaka …

Science (New York, N.Y.), 354(6319) 1552-1557, Dec 23, 2016 Peer-reviewed

Mutational and crystallographic analysis of l-amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813: Interconversion between oxidase and monooxygenase activities.

Daisuke Matsui, Do-Hyun Im, Asami Sugawara, Yasuhisa Fukuta, Shinya Fushinobu, Kimiyasu Isobe, Yasuhisa Asano

FEBS open bio, 4 220-8, 2014 Peer-reviewedLead author

Crystal structures of glycoside hydrolase family 51 α-L-arabinofuranosidase from Thermotoga maritima.

Do-Hyun Im, Kei-ichi Kimura, Fumitaka Hayasaka, Tomonari Tanaka, Masato Noguchi, Atsushi Kobayashi, Shin-ichiro Shoda, Kentaro Miyazaki, Takayoshi Wakagi, Shinya Fushinobu

Bioscience, biotechnology, and biochemistry, 76(2) 423-8, 2012 Peer-reviewedLead author

Papers

Menu

Coauthors