バードリアム (Liam Baird) - マイポータル

基本情報

所属: 東北大学

研究者番号: 90724914
J-GLOBAL ID: 201801007153946941
researchmap会員ID: B000308861

研究分野

ライフサイエンス / 分子生物学 /

論文

Whole blood transcriptome analysis for age- and gender-specific gene expression profiling in Japanese individuals.

Yu-Ichi Aoki, Keiko Taguchi, Hayato Anzawa, Junko Kawashima, Noriko Ishida, Akihito Otuki, Atsushi Hasegawa, Liam Baird, Takafumi Suzuki, Ikuko N Motoike …

Journal of biochemistry 2024年1月24日
Immunoediting of KEAP1-NRF2 mutant tumours is required to circumvent NRF2-mediated immune surveillance

Liam Baird, Masayuki Yamamoto

Redox Biology 67 102904-102904 2023年11月
A NRF2-induced secretory phenotype activates immune surveillance to remove irreparably damaged cells

Liam Baird, Keiko Taguchi, Anqi Zhang, Yushi Takahashi, Takafumi Suzuki, Thomas W. Kensler, Masayuki Yamamoto

Redox Biology 66 102845-102845 2023年10月
Novel NRF2-activated cancer treatments utilizing synthetic lethality.

Liam Baird, Thomas W Kensler, Masayuki Yamamoto

IUBMB life 2022年10月5日
NRF2-dependent bioactivation of mitomycin C as a novel strategy to target KEAP1-NRF2 pathway activation in human cancer.

Liam Baird, Masayuki Yamamoto

Molecular and cellular biology 41(2) 2020年11月2日
Geldanamycin-Derived HSP90 Inhibitors Are Synthetic Lethal with NRF2.

Liam Baird, Takafumi Suzuki, Yushi Takahashi, Eiji Hishinuma, Daisuke Saigusa, Masayuki Yamamoto

Molecular and cellular biology 40(22) 2020年10月26日
The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway.

Liam Baird, Masayuki Yamamoto

Molecular and cellular biology 40(13) 2020年6月15日
Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap1.

Suzuki T, Muramatsu A, Saito R, Iso T, Shibata T, Kuwata K, Kawaguchi SI, Iwawaki T, Adachi S, Suda H …

Cell reports 28(3) 746-758 2019年7月16日査読有り
A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways

Liam Baird, Tadayuki Tsujita, Eri H. Kobayashi, Ryo Funayama, Takeshi Nagashima, Keiko Nakayama, Masayuki Yamamoto

MOLECULAR AND CELLULAR BIOLOGY 37(4) E00651-U199 2017年2月査読有り
Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus

Takafumi Suzuki, Shiori Seki, Keiichiro Hiramoto, Eriko Naganuma, Eri H. Kobayashi, Ayaka Yamaoka, Liam Baird, Nobuyuki Takahashi, Hiroshi Sato, Masayuki Yamamoto

NATURE COMMUNICATIONS 8 14577 2017年2月査読有り
Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells

Tatsuro Iso, Takafumi Suzuki, Liam Baird, Masayuki Yamamoto

MOLECULAR AND CELLULAR BIOLOGY 36(24) 3100-3112 2016年12月査読有り
NRF2 Intensifies Host Defense Systems to Prevent Lung Carcinogenesis, but After Tumor Initiation Accelerates Malignant Cell Growth

Hironori Satoh, Takashi Moriguchi, Daisuke Saigusa, Liam Baird, Lei Yu, Hirofumi Rokutan, Keiko Igarashi, Masahito Ebina, Tatsuhiro Shibata, Masayuki Yamamoto

CANCER RESEARCH 76(10) 3088-3096 2016年5月査読有り
Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response

Saito R, Suzuki T, Hiramoto K, Asami S, Naganuma E, Suda H, Iso T, Yamamoto H, Morita M, Baird L …

Mol Cell Biol 36(2) 271-284 2016年1月査読有り
Design, Synthesis, and Evaluation of Triazole Derivatives That Induce Nrf2 Dependent Gene Products and Inhibit the Keap1-Nrf2 Protein-Protein Interaction

Bertrand HC, Schaap M, Baird L, Georgakopoulos ND, Fowkes A, Thiollier C, Kachi H, Dinkova-Kostova AT, Wells G

J Med Chem 58(18) 7186-7194 2015年9月査読有り
The spatiotemporal regulation of the Keap1-Nrf2 pathway and its importance in cellular bioenergetics

Biochem Soc Trans 43 602-610 2015年8月査読有り
Discovery of an NRF1-specific inducer from a large-scale chemical library using a direct NRF1-protein monitoring system

Tadayuki Tsujita, Liam Baird, Yuki Furusawa, Fumiki Katsuoka, Yoshika Hou, Satomi Gotoh, Shin-ichi Kawaguchi, Masayuki Yamamoto

GENES TO CELLS 20(7) 563-577 2015年7月査読有り
Hypoxia-Sensitive Reporter System for High-Throughput Screening

Tadayuki Tsujita, Shin-ichi Kawaguchi, Takashi Dan, Liam Baird, Toshio Miyata, Masayuki Yamamoto

TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE 235(2) 151-159 2015年2月査読有り
Monitoring Keap1-Nrf2 interactions in single live cells

Biotechnol Adv 32(6) 1133-1144 2014年11月査読有り
Transcription Factor Nrf1 Negatively Regulates the Cystine/Glutamate Transporter and Lipid-Metabolizing Enzymes

Tadayuki Tsujita, Vivian Peirce, Liam Baird, Yuka Matsuyama, Misaki Takaku, Shawn V. Walsh, Julian L. Griffin, Akira Uruno, Masayuki Yamamoto, John D. Hayes

MOLECULAR AND CELLULAR BIOLOGY 34(20) 3800-3816 2014年10月査読有り
Regulatory flexibility in the Nrf2-mediated stress response is conferred by conformational cycling of the Keap1-Nrf2 protein complex

Baird L, Llères D, Swift S, Dinkova-Kostova AT

Proc Natl Acad Sci U S A 110(38) 15259-15264 2013年9月査読有り

もっとみる

共同研究・競争的資金等の研究課題

Keap1-Nrf2系によるストレス感知機構

日本学術振興会科学研究費助成事業若手研究(B) 2017年4月 - 2019年3月

鈴木隆史, 山本雅之, 磯達朗, 村松亜紀, 齋藤良太, 須田博美, 守田匡伸
An investigation into the mechanism regulating the oxidative stress-dependent activation of the Keap1-Nrf2 pathway

日本学術振興会科学研究費助成事業若手研究(B) 2016年4月 - 2019年3月

Baird Liam, 山本雅之, 鈴木隆史

バードリアム

基本情報

研究分野

論文

共同研究・競争的資金等の研究課題

メニュー

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