論文

査読有り 筆頭著者
2019年

Hashimoto's Encephalopathy Presenting with Smoldering Limbic Encephalitis.

Internal medicine (Tokyo, Japan)
  • Masahiro Nagano
  • ,
  • Katsuya Kobayashi
  • ,
  • Mayumi Yamada-Otani
  • ,
  • Akira Kuzuya
  • ,
  • Riki Matsumoto
  • ,
  • Jiro Oita
  • ,
  • Makoto Yoneda
  • ,
  • Akio Ikeda
  • ,
  • Ryosuke Takahashi

58
8
開始ページ
1167
終了ページ
1172
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.2169/internalmedicine.1289-18

Hashimoto's encephalopathy (HE) is a steroid-responsive autoimmune encephalopathy associated with Hashimoto thyroiditis. We herein report a case of HE manifesting "smoldering" limbic encephalitis with persisting symptoms and abnormalities on examinations. Although our patient experienced partial clinical remission after treatment, hippocampal hypermetabolism on [18F] fluorodeoxyglucose positron emission tomography (FDG-PET) and subclinical seizures on video electroencephalography persisted. Hypermetabolism on FDG-PET was improved by additional prednisolone therapy. Thus, as with other autoimmune limbic encephalitis cases, HE can take a course of "smoldering" encephalitis. FDG-PET and electroencephalogram findings can reflect the disease activity degree in such patients, although with certain neurophysiological and biochemical distinctions.

リンク情報
DOI
https://doi.org/10.2169/internalmedicine.1289-18
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/30982805
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522399
ID情報
  • DOI : 10.2169/internalmedicine.1289-18
  • PubMed ID : 30982805
  • PubMed Central 記事ID : PMC6522399

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