論文

査読有り 筆頭著者
2019年

Recurrent Epstein-Barr Virus-positive (EBV+) Primary Central Nervous System Lymphoma (PCNSL) in a Patient with Clinical Features of Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS).

Internal medicine (Tokyo, Japan)
  • Masahiro Nagano
  • ,
  • Takashi Ayaki
  • ,
  • Natsuko Koita
  • ,
  • Toshiyuki Kitano
  • ,
  • Momoko Nishikori
  • ,
  • Naoki Goda
  • ,
  • Sachiko Minamiguchi
  • ,
  • Akio Ikeda
  • ,
  • Akifumi Takaori-Kondo
  • ,
  • Ryosuke Takahashi

58
6
開始ページ
849
終了ページ
854
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.2169/internalmedicine.1246-18

Primary central nervous system lymphoma (PCNSL) and chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) can share clinical features and may be indistinguishable, even after brain biopsy. We encountered a case of Epstein-Barr virus-positive (EBV+) PCNSL recurrence in a patient with clinical features of CLIPPERS, and repeat brain biopsy was required to reach the correct diagnosis. Four years after the initial diagnosis and treatment of PCNSL, "peppering" punctate enhanced lesions with transient steroid responsiveness were detected during brain magnetic resonance imaging (MRI). A second brain biopsy supported a diagnosis of CLIPPERS, while a third biopsy confirmed the diagnosis of recurrent PCNSL.

リンク情報
DOI
https://doi.org/10.2169/internalmedicine.1246-18
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/30880301
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465023
ID情報
  • DOI : 10.2169/internalmedicine.1246-18
  • PubMed ID : 30880301
  • PubMed Central 記事ID : PMC6465023

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