2017年9月
Stimulators of acylated ghrelin secretion from Moringa oleifera leaves
Phytochemistry Letters
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- 巻
- 21
- 号
- 開始ページ
- 1
- 終了ページ
- 5
- 記述言語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.phytol.2017.04.022
© 2017 A new nitrogen-containing phenolic glycoside, moringaside A (1), and a new megastigmane glycoside, moringamegastigmane A (2), were isolated from the leaves of Moringa oleifera together with 16 known compounds. The chemical structures of the isolated compounds were elucidated on the basis of chemical and physicochemical evidence. To the best of our knowledge, there are few reports of compounds that effect acylated ghrelin secretion. Among the constituents of M. oleifera, niazirin (5) significantly stimulated the secretion of acylated ghrelin in vitro using rat primary gastric cells. This result suggests that 5 is a promising therapeutic agent for anorexia.
- リンク情報
- ID情報
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- DOI : 10.1016/j.phytol.2017.04.022
- ISSN : 1874-3900
- eISSN : 1876-7486
- SCOPUS ID : 85019930122