井上誠 (Makoto Inoue) - マイポータル

基本情報

所属: 株式会社インファーマシア

研究者番号: 80900729
J-GLOBAL ID: 202401003647758880
researchmap会員ID: R000067657

研究キーワード

研究分野

学歴

1997年4月 - 2000年10月

京都大学大学院, 農学研究科, 博士後期課程

論文

Discovery of a 1-isopropyltetrahydroisoquinoline derivative as an orally active N-type calcium channel blocker for neuropathic pain

Takashi Ogiyama, Koichi Yonezawa, Makoto Inoue, Toshihiro Watanabe, Yukihito Sugano, Takayasu Gotoh, Tetsuo Kiso, Akiko Koakutsu, Shuichiro Kakimoto, Jun-ichi Shishikura

Bioorganic & Medicinal Chemistry 23(15) 4624-4637 2015年8月
Discovery of an 8-methoxytetrahydroisoquinoline derivative as an orally active N-type calcium channel blocker for neuropathic pain without CYP inhibition liability

Takashi Ogiyama, Koichi Yonezawa, Makoto Inoue, Naoko Katayama, Toshihiro Watanabe, Seiji Yoshimura, Takayasu Gotoh, Tetsuo Kiso, Akiko Koakutsu, Shuichiro Kakimoto …

Bioorganic & Medicinal Chemistry 23(15) 4638-4648 2015年8月
Discovery of novel tetrahydroisoquinoline derivatives as orally active N-type calcium channel blockers with high selectivity for hERG potassium channels

Takashi Ogiyama, Makoto Inoue, Shugo Honda, Hiroyoshi Yamada, Toshihiro Watanabe, Takayasu Gotoh, Tetsuo Kiso, Akiko Koakutsu, Shuichiro Kakimoto, Jun-ichi Shishikura

Bioorganic & Medicinal Chemistry 22(24) 6899-6907 2014年12月
Macromolecular Uptake of Alkyl‐Chain‐Modified Guanidinoglycoside Molecular Transporters

Makoto Inoue, Ezequiel Wexselblatt, Jeffrey D. Esko, Yitzhak Tor

ChemBioChem 15(5) 676-680 2014年2月20日
Aggregation-Mediated Macromolecular Uptake by a Molecular Transporter

Makoto Inoue, Wenyong Tong, Jeffrey D. Esko, Yitzhak Tor

ACS Chemical Biology 8(7) 1383-1388 2013年4月26日
γ-Glutamyltranspeptidase and γ-Glutamyl Peptide Ligases: Fluorophosphonate and Phosphonodifluoromethyl Ketone Analogs as Probes of Tetrahedral Transition State and γ-Glutamyl-Phosphate Intermediate

Jun Hiratake, Makoto Inoue, Kanzo Sakata

Enzyme Kinetics and Mechanism - Part F: Detection and Characterization of Enzyme Reaction Intermediates 272-295 2002年
Identification of Catalytic Nucleophile of Escherichia coli γ-Glutamyltranspeptidase by γ-Monofluorophosphono Derivative of Glutamic Acid: N-Terminal Thr-391 in Small Subunit Is the Nucleophile

Makoto Inoue, Jun Hiratake, Hideyuki Suzuki, Hidehiko Kumagai, Kanzo Sakata

Biochemistry 39(26) 7764-7771 2000年6月9日
Synthesis and Characterization of Intermediate and Transition-State Analogue Inhibitors of γ-Glutamyl Peptide Ligases

Makoto INOUE, Jun HIRATAKE, Kanzo SAKATA

Bioscience, Biotechnology, and Biochemistry 63(12) 2248-2251 1999年1月

産業財産権

PCT/JP2024/003437 培養装置、培養組織、培養組織の製造方法及び評価法

井上誠