2015年
Expression of Sox genes in tooth development
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- 巻
- 59
- 号
- 10-12
- 開始ページ
- 471
- 終了ページ
- 478
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1387/ijdb.150192ao
- 出版者・発行元
- UNIV BASQUE COUNTRY UPV-EHU PRESS
Members of the Sox gene family play roles in many biological processes including organogenesis. We carried out comparative in situ hybridization analysis of seventeen sox genes (Sox 1-14, 17, 18, 21) during murine odontogenesis from the epithelial thickening to the cytodifferentiation stages. Localized expression of five Sox genes (Sox6, 9, 13, 14 and 21) was observed in tooth bud epithelium. Sox13 showed restricted expression in the primary enamel knots. At the early bell stage, three Sox genes (Sox8, 11, 17 and 21) were expressed in pre-ameloblasts, whereas two others (Sox5 and 18) showed expression in odontoblasts. Sox genes thus showed a dynamic spatio-temporal expression during tooth development.
- リンク情報
- ID情報
-
- DOI : 10.1387/ijdb.150192ao
- ISSN : 0214-6282
- eISSN : 1696-3547
- PubMed ID : 26864488
- Web of Science ID : WOS:000372858700008