Objective：The level of sensory processing dysfunction was examined and compared with the severity of food-related behaviors and aberrant behaviors in 102 individuals (60 males and 42 females) with Prader-Willi syndrome (PWS), including 76 patients with paternally inherited deletion and 26 patients with maternal uniparental disomy within the 15q11-13 region. Methods：The Japanese version of the Short Sensory Profile (SSP-J), the Food Related Problem Ques-tionnaire (FRPQ) and Aberrant Behavior Checklist Japanese Version (ABC-J) were administered to PWS patients. Results：Based on the results of SSP-J, the patients in this study were classified as follows：27 individuals with Typical Performance, 45 with Probable Difference and 30 with Definite Difference. Among the three groups, one-way analyses of variance (ANOVAs) were conducted to investigate differences in scores of FRPQ and ABC-J. No significant differences were found in the total scores and three subscores of FRPQ. On the contrary, statistically significant differences were found in the total score as well as five subscores in the ABC-J. Post-hoc Tukey’s tests revealed significant differences of aberrant behaviors in the total score and all of the five subscores of the ABC-J. Definite Difference was more than Probable Difference and Typical Performance. Conclusions：Approximately three quarters of individuals with PWS demonstrated abnormalities in sensory responsiveness. In terms of the relationships of sensory processing with other behavioral symptoms, aberrant behaviors and food-related problems brought out a sharp contrast；the former showed significant associations with sensory processing, whereas the latter did not.