Marie Saitou - My portal - researchmap

Profile Information

Affiliation: Tenure-Track Principal Investigator, Centre of Integrative Genetics (CIGENE), ノルウェー生命科学大学

Degree: 理学博士(Mar, 2017, 東京大学)

ORCID iD: https://orcid.org/0000-0002-8794-3217
J-GLOBAL ID: 201501010955760508
researchmap Member ID: B000247651

External link: https://sites.google.com/view/saitou-lab/home

Up-to-date information
https://sites.google.com/site/mariesaitou/english

Research Interests

3

Research Areas

1

Life sciences / Evolutionary biology /

Research History

3

2020 - 2026

(Tenure-Track Principal Investigator), Norwegian University of Life Sciences
2020 - 2020

Postdoctoral Scholar, シカゴ大学
2017 - 2020

PostDoc. Biological Sciences, University at Buffalo (Advisor: Dr. Omer Gokcumen)

Education

2

2012 - 2017

Department of Biological Sciences, Graduate School of Science, The University of Tokyo
2008 - 2012

Department of Biological Sciences, The University of Tokyo

Awards

12

2021

The Norwegian Talent Development Programme 2.0, Norway
2020

“Reviewers’ Choice” award, American Society of Human Genetics meeting
2020

The Genetics Society of America travel award
2019

Excellent Oral Presentation Award, 21st meeting of the Society of Evolutionary Studies, Japan
2019

DeLill Nasser Award, Genetic Society of America
2019

Young Investigator Award, Society for Molecular Biology and Evolution meeting
2018

Travel Award, Society for Molecular Biology and Evolution meeting

Marie Saitou
2018

Three-Minute Presentation: First Place, Tenth Annual Postdoctoral Research Symposium, June 13, 2018, University at Buffalo, USA.

Marie Saitou
2016

Best Question Award, HOPE meeting with Nobel laureates, Japan

Marie Saitou
2016

ASN Young Scientist Oral Presentation Award, The 70th Annual Meeting of Anthropological Society of Nippon, Oct.8-10, 2016, Niigata, Japan

Marie Saitou
2012

School of Science Award, the University of Tokyo, Japan

Marie Saitou
2011

Prize at the paper competition for students in Science and Technology, newspaper of The Daily Industrial News, Japan

Marie Saitou

Papers

12

Allele frequency differences of causal variants have a major impact on low cross-ancestry portability of PRS

Saitou M, Dahl A, Wang Q, Liu X

Oct, 2022
The emergence of supergenes from inversions in Atlantic salmon

Kristina Stenløkk, Marie Saitou, Live Rud-Johansen, Torfinn Nome, Michel Moser, Mariann Árnyasi, Matthew Kent, Nicola Barson, Sigbjorn Lien

Philosophical Transactions of the Royal Society B: Biological Sciences, 377(1856), Aug, 2022
Similarity-based analysis of allele frequency distribution among multiple populations identifies adaptive genomic structural variants

Marie Saitou, Naoki Masuda, Omer Gokcumen

Molecular Biology and Evolution, Oct 28, 2021
Functional Specialization of Human Salivary Glands and Origins of Proteins Intrinsic to Human Saliva

Marie Saitou, Eliza A. Gaylord, Erica Xu, Alison J. May, Lubov Neznanova, Sara Nathan, Anissa Grawe, Jolie Chang, William Ryan, Stefan Ruhl …

Cell Reports, 33(7) 108402-108402, Nov, 2020 Peer-reviewed
An Evolutionary Perspective on the Impact of Genomic Copy Number Variation on Human Health

Marie Saitou, Omer Gokcumen

Journal of Molecular Evolution, 88(1) 104-119, Jan, 2020 Peer-reviewed
Sex-specific phenotypic effects and evolutionary history of an ancient polymorphic deletion of the human growth hormone receptor

Marie Saitou, Skyler Resendez, Apoorva J Pradhan, Fuguo Wu, Natasha C Lie, Nancy J Hall, Qihui Zhu, Laura Reinholdt, Yoko Satta, Shigeki Nakagome …

Science advances, Oct 1, 2019
Resolving the Insertion Sites of Polymorphic Duplications Reveals a HERC2 Haplotype under Selection

Marie Saitou, Omer Gokcumen

Genome Biology and Evolution, 11(6) 1679-1690, Jun 1, 2019 Peer-reviewed
The Role of p38 MAPK in Triacylglycerol Accumulation During Apoptosis

Nasi Li, Marie Saitou, G. Ekin Atilla‐Gokcumen

PROTEOMICS, 1900160-1900160, May 17, 2019 Peer-reviewed
Complex Haplotypes ofGSTM1Gene Deletions Harbor Signatures of a Selective Sweep in East Asian Populations

Marie Saitou, Yoko Satta, Omer Gokcumen

G3&#58; Genes|Genomes|Genetics, g3.200462.2018, Jul, 2018 Peer-reviewed
Complex evolution of the GSTM gene family involves sharing of GSTM1 deletion polymorphism in humans and chimpanzees

M. Saitou, Y. Satta, O. Gokcumen, T. Ishida

BMC Genomics, 19(1), Apr, 2018 Peer-reviewed
An evolutionary transcriptomics approach links CD36 to membrane remodeling in replicative senescence

Marie Saitou, Darleny Y. Lizardo, Recep Ozgur Taskent, Alec Millner, Omer Gokcumen, Gunes Ekin Atilla-Gokcumen

Molecular Omics, 14(4) 237-246, 2018 Peer-reviewed
Distributions of the GSTM1 and GSTT1 Null Genotypes Worldwide are Characterized by Latitudinal Clines

Marie Saitou, Takafumi Ishida

Asian Pacific Journal of Cancer Prevention, 16(1) 355-361, Feb 4, 2015 Peer-reviewed

Presentations

17

Understanding the transethnic genetic architecture of gene expression

Saitou M, Liu X

American Society of Human Genetics meeting, 2020
Integrative selection analysis on human structural variants reveals putatively adaptive loci with unusual population differentiation

Saitou M, Masuda N, Gokcumen O

Society for Molecular Biology and Evolution meeting, 2020
A new mouse model sheds light on the evolutionary impact of an ancient deletion polymorphism in the human growth hormone receptor gene

Saitou M, Resendez S, Dean K, Shaner-Tooley C, Wu F, Mu, Gokcumen O

The Allied Genetics Conference, 2020
Functional specialization of human salivary glands and origins of proteins intrinsic to human saliva

Saitou M

163rd Meeting of the Japanese Veterinary Anatomy, 2020
A haplotype-level analysis reveals adaptive polymorphic gene duplications in humans affecting pigmentation and hair morphology

Saitou M, Gokcumen O

American Association of Physical Anthropologists meeting, Cleveland, US, 2019
Comparative RNA-seq sheds light on functional and evolutionary differentiation of human major salivary glands

Saitou M, Xu, D. Ruhl, S. Knox, S. Gokcumen O

Salivary Glands and Exocrine Biology, Gordon Research Conference, Texas, US, 2019
A new linkage-disequilibrium based method to detect insertion sites of polymorphic duplications

Saitou M

21st meeting of the Society of Evolutionary Studies, Japan, 2019
A new mouse model sheds light on the evolutionary impact of an ancient deletion polymorphism in the human growth hormone receptor gene

Saitou M, Resendez S, Dean K, Shaner-Tooley C, Wu F, Mu, Gokcumen O

21st meeting of the Society of Evolutionary Studies, Japan, 2019
A new mouse model sheds light on the evolutionary impact of an ancient deletion polymorphism in the human growth hormone receptor gene

Saitou M, Resendez S, Dean K, Shaner-Tooley C, Wu F, Mu, Gokcumen O

Society for Molecular Biology and Evolution meeting, Manchester, UK, 2019
Comparative RNA-seq sheds light on functional and evolutionary differentiation of human major salivary glands

Saitou M, Xu, D. Ruhl, S. Knox, S. Gokcumen O

Salivary Glands and Exocrine Biology, Gordon Research Seminar, Texas,, 2019
Resolving the evolutionary impact of polymorphic gene duplications in humans at the haplotype level

Saitou M, Gokcumen O

Society for Molecular Biology and Evolution meeting, Yokohama, Japan, 2018
Adaptive evolution of complex haplotypes harboring the metabolizing the GSTM1 gene deletion

Saitou M, Satta Y, Gokcumen O

American Association of Physical Anthropologists meeting, Austin, 2018
Evolutionary forces shaping the distribution of the GSTM1 gene deletion in humans

Saitou M, Satta Y, Gokcumen O

Society for Molecular Biology and Evolution meeting, 2017
Evolution of deletion polymorphism of the gene for a cellular metabolizing enzyme glutathione-s-transferase μ1 in humans and chimpanzees

Saitou M, Ishida T, Satta Y, Gokcumen O

The Biology of Genomes Meeting, Cold Spring Harbor Laboratory, U.S., 2017
A hotspot of chromosomal rearrangements was revealed by comparative Hominidae genomics

Saitou M

HOPE meeting with Nobel laureates, Tsukuba, Japan, 2016
Evolutionary analysis of deletion polymorphism of the entire GSTM (glutathione S-transferase mu) 1 gene generated by a homologous chromosomal recombination suggests multiple deletion events

Saitou M, Ishida T

Society for Molecular Biology and Evolution meeting, Vienna, Austria, 2015
Distributions of the GSTT1 null genotype worldwide is characterized by a latitudinal cline

Saitou M, Ishida T

International Society for Applied Biological Sciences, Bol, Croatia, 2015

Teaching Experience

2

Professional Memberships

3

Research Projects

5

"Unveiling the evolutionary and functional impact of genomic structural variants of Atlantic salmon", (NOK 8M, $940K)

Researcher Project for Young Talents (FRIPRO) grant, the Research Council of Norway,, Jul, 2021 - Jun, 2024
A preliminary analysis of genomic structural variants in Atlantic salmon

Norwegian University of Life Sciences, 2021
Astellas Foundation for Research Abroad on Metabolic Disorders, Japan

2017 - 2018

Marie Saitou
Research Fellow of the Japan Society for the Promotion of Science (DC1)

2014 - 2017

Marie Saitou
Graduate Program for Leaders in Life Innovation (GPLLI), Japan

2013 - 2017

Marie Saitou

Media Coverage

4

Scientists finally know how we make saliva

Partner.sciencenorway.no, https://partner.sciencenorway.no/health-nmbu/scientists-finally-know-how-we-make-saliva/1784611, 2020
The story on spit

Canadian Broadcasting Corporation, https://www.cbc.ca/listen/live-radio/1-52-radio-active/clip/15809772-the-story-spit, 2020
Cells stop dividing when this gene kicks into high gear, study finds

UB News Center, http://www.buffalo.edu/news/releases/2018/06/011.html, 2018
Internet mentoring leads to postdoc fellowship

UBNow, http://www.buffalo.edu/ubnow/stories/2017/06/postdoc-symposium.htm, 2017