Research Projects

Apr, 2019 - Mar, 2022

Pathology and treatment for dry age-related macular degeneration using adaptive optics OCT

Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)  Grant-in-Aid for Scientific Research (C)
  • Sotaro Ooto

Grant number
19K09948
Japan Grant Number (JGN)
JP19K09948
Grant amount
(Total)
4,290,000 Japanese Yen
(Direct funding)
3,300,000 Japanese Yen
(Indirect funding)
990,000 Japanese Yen

We firstly reported cone cell body and Muller cells in normal eyes using adaptive optics OCT. Mean total size and each size of flow voids, which shows spaces among mesh work structures of choriocapillaris, were 0.99 mm2 and 567.8 μm2. They were correlated negatively with age.
Mean cone cell body density 0.5 mm apart from geographic atrophy was significantly reduced in eyes with dry AMD, compared with normal eyes. These results were remarkable in eyes with pseudodrusen. We firstly reported deposits under retinal pigment epithelium using adaptive optics OCT.

Link information
KAKEN
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19K09948
ID information
  • Grant number : 19K09948
  • Japan Grant Number (JGN) : JP19K09948