Masanori Matsuzaki

Profile Information

Affiliation: Graduate School of Medicine, The University of Tokyo

J-GLOBAL ID: 200901089800632837
researchmap Member ID: 5000090865

External link: http://plaza.umin.ac.jp/~Matsuzaki-Lab/

Research Areas

Research History

Apr, 2016 - Present

Graduate School of Medicine, The University of Tokyo
Sep, 2010

National Institutes of Natural Sciences
2008 - 2010

准教授, 東京大学医学(系)研究科(研究院)
2006 - 2008

Graduate School of Medicine, The University of Tokyo
2004 - 2005

National Institute for Physiological Sciences
2004

Department of Cell Physiology, National Institute for Physiological Sciences
2003

助手, 岡崎国立共同研究機構・生理学研究所

Awards

Papers

Movement-independent representation of reward-predicting cues in the medial part of the primate premotor cortex

Keisuke Sehara, Masashi Kondo, Yuka Hirayama, Teppei Ebina, Masafumi Takaji, Akiya Watakabe, Ken-ichi Inoue, Masahiko Takada, Tetsuo Yamamori, Masanori Matsuzaki

Aug 26, 2024
Medial prefrontal cortex suppresses reward-seeking behavior with risk of punishment by reducing sensitivity to reward

Monami Nishio, Masashi Kondo, Eriko Yoshida, Masanori Matsuzaki

Frontiers in Neuroscience, 18, Jun 5, 2024
ARViS: A bleed-free multi-site automated injection robot for accurate, fast, and dense delivery of virus to mouse and marmoset brains

Shinosuke Nomura, Shin-Ichiro Terada, Teppei Ebina, Masato Uemura, Yoshito Masamizu, Kenichi Ohki, Masanori Matsuzaki

Jan 15, 2024
Change detection in the primate auditory cortex through feedback of prediction error signals

Keitaro Obara, Teppei Ebina, Shin-Ichiro Terada, Takanori Uka, Misako Komatsu, Masafumi Takaji, Akiya Watakabe, Kenta Kobayashi, Yoshito Masamizu, Hiroaki Mizukami …

Nature Communications, 14(1), Nov 13, 2023
Dynamics of motor direction representation in the primate premotor and primary motor cortices during sensorimotor learning

Teppei Ebina, Akitaka Sasagawa, Dokyeong Hong, Rieko Setsuie, Keitaro Obara, Yoshito Masamizu, Masashi Kondo, Shin-Ichiro Terada, Katsuya Ozawa, Masato Uemura …

Sep 14, 2023
Layer 5 intratelencephalic neurons in the motor cortex stably encode skilled movement

Takanori Shinotsuka, Yasuhiro R. Tanaka, Shin-Ichiro Terada, Natsuki Hatano, Masanori Matsuzaki

The Journal of Neuroscience, JN-RM, Sep 12, 2023
Negative reward-prediction errors of climbing fiber inputs for cerebellar reinforcement learning algorithm

Huu Hoang, Shinichiro Tsutsumi, Masanori Matsuzaki, Masanobu Kano, Keisuke Toyama, Kazuo Kitamura, Mitsuo Kawato

Mar 13, 2023
Dynamic organization of cerebellar climbing fiber response and synchrony in multiple functional modules reduces dimensions for reinforcement learning

Huu Hoang, Shinichiro Tsutsumi, Masanori Matsuzaki, Masanobu Kano, Mitsuo Kawato, Kazuo Kitamura, Keisuke Toyama

Dec 5, 2022
Silent microscopy to explore a brain that hears butterflies’ wings

Shin-Ichiro Terada, Masanori Matsuzaki

Light: Science & Applications, 11(1), Dec, 2022
Transition of distinct context-dependent ensembles from secondary to primary motor cortex in skilled motor performance

Shin-Ichiro Terada, Kenta Kobayashi, Masanori Matsuzaki

Cell Reports, 41(3) 111494-111494, Oct, 2022
Optical deep-cortex exploration in behaving rhesus macaques

Masanori Matsuzaki, Teppei Ebina

Nature Communications, 12(1), Dec, 2021
A small-scale robotic manipulandum for motor control study with rodents

Takahisa Inoue, Shin-Ichiro Terada, Masanori Matsuzaki, Jun Izawa

Advanced Robotics, 35(13-14) 898-906, Jul 18, 2021 Peer-reviewed
Neuronal representations of reward-predicting cues and outcome history with movement in the frontal cortex.

Masashi Kondo, Masanori Matsuzaki

Cell reports, 34(5) 108704-108704, Feb 2, 2021
Tb3+-doped fluorescent glass for biology.

Kazuki Okamoto, Teppei Ebina, Naoki Fujii, Kuniaki Konishi, Yu Sato, Tetsuhiko Kashima, Risako Nakano, Hiroyuki Hioki, Haruki Takeuchi, Junji Yumoto …

Science advances, 7(2), Jan, 2021
Common marmoset as a model primate for study of the motor control system

Matsuzaki M., Ebina T.

Current Opinion in Neurobiology, 64 103-110, Oct, 2020 Peer-reviewedInvited
Non-action Learning: Saving Action-Associated Cost Serves as a Covert Reward

Sai Tanimoto, Masashi Kondo, Kenji Morita, Eriko Yoshida, Masanori Matsuzaki

Frontiers in Behavioral Neuroscience, 14 141-141, Sep 4, 2020 Peer-reviewed
Structural dynamics and stability of corticocortical and thalamocortical axon terminals during motor learning

Ryota Hasegawa, Teppei Ebina, Yasuhiro R. Tanaka, Kenta Kobayashi, Masanori Matsuzaki

PLOS ONE, 15(6) e0234930-e0234930, Jun 19, 2020 Peer-reviewed
Motor learning requires myelination to reduce asynchrony and spontaneity in neural activity.

Daisuke Kato, Hiroaki Wake, Philip R Lee, Yoshihisa Tachibana, Riho Ono, Shouta Sugio, Yukio Tsuji, Yasuyo H Tanaka, Yasuhiro R Tanaka, Yoshito Masamizu …

Glia, 68(1) 193-210, Jan, 2020 Peer-reviewed
Independent representations of reward-predicting cues and reward history in frontal cortical neurons

Masashi Kondo, Masanori Matsuzaki

Jan, 2020
Arm movements induced by noninvasive optogenetic stimulation of the motor cortex in the common marmoset

Teppei Ebina, Keitaro Obara, Akiya Watakabe, Yoshito Masamizu, Shin-Ichiro Terada, Ryota Matoba, Masafumi Takaji, Nobuhiko Hatanaka, Atsushi Nambu, Hiroaki Mizukami …

Proceedings of the National Academy of Sciences, 116(45) 22844-22850, Nov 5, 2019 Peer-reviewed

Misc.

神経活動依存性髄鞘化のメカニズムと情報処理への寄与

和氣弘明, 加藤大輔, 穐吉亮平, 松崎政紀

応用薬理, 85(1) 50-50, Aug 26, 2013
Two-Photon Imaging and Photomanipulation of Multicellular Neural Activity in Awake Behaving Animals

MATSUZAKI MASANORI, HIRA RIICHIRO, OKUBO FUKI

レーザー研究, 41(2) 86-91, Feb, 2013
新しいプレクリニカルの技術展開―トランスレーションに向けて―2.光技術を用いた神経回路機能の解読と操作

尾藤晴彦, 松崎政紀, 吉村由美子, 古田寿昭

実験医学, 30(13) 2080-2086, Aug 1, 2012
オプトジェネティックスの最前線

松崎政紀

化学と生物, 50(6) 406-413, Jun 1, 2012
生きたままの姿を見る4Dイメージング光操作技術を駆使した神経科学研究の新展開

松崎政紀

実験医学, 29(16) 2618-2622, Oct 1, 2011
A rapid genetic strategy for multiple-gene, single-neuron labeling in the living rodent brain

Rie Ako, Haruka Ebisu, Mayu Wakimoto, Kaori Tanno, Riichiro Hira, Haruo Kasai, Masanori Matsuzaki, Hiroshi Kawasaki

NEUROSCIENCE RESEARCH, 71 E412-E412, 2011
P2-u14 In vivo two-photon uncaging of glutamate revealing the structure-function relationships of dendritic spines in the neocortex of adult mice

Jun Noguchi, Akira Nagaoka, Satoshi Watanabe, Graham C. R. Ellis-Davies, Kazuo Kitamura, Masanobu Kano, Masanori Matsuzaki, Haruo Kasai

NEUROSCIENCE RESEARCH, 71 E206-E206, 2011
Optogenetic functional tracing for identifying functional connections between cortical motor areas in vivo

Fuki Ohkubo, Riichiro Hira, Haruo Kasai, Masanori Matsuzaki

NEUROSCIENCE RESEARCH, 71 E312-E312, 2011
GABA dependence of glutamate-mediated shrinkage and elimination of dendritic spines revealed with two-color uncaging of glutamate and GABA

Tatsuya Hayama, Yuya Kanemoto, Masanori Matsuzaki, Graham C. R. Ellis-Davies, Haruo Kasai

NEUROSCIENCE RESEARCH, 68 E340-E340, 2010
Two-color, two-photon uncaging of glutamate and GABA

Yuya Kanemoto, Masanori Matsuzaki, Haruo Kasai

NEUROSCIENCE RESEARCH, 68 E234-E234, 2010
Optical stimulation of synapses and neurons

Masanori Matsuzaki, Graham C. R. Ellis-Davies, Tatsuya Hayama, Yuya Kanemoto, Haruo Kasai

NEUROSCIENCE RESEARCH, 68 E26-E26, 2010
Long-term dynamics of dendritic spines in hippocampal slice culture

Cell technology., 28(9) 886-891, Sep, 2009
TRANSCRANIAL OPTOGENETIC STIMULATION FOR FUNCTIONAL MAPPING OF THE MOUSE MOTOR CORTEX

Masanori Matsuzaki, Riichiro Hira, Naoki Honkura, Jun Noguchi, Yoshio Maruyama, George J. Augustine, Haruo Kasai

JOURNAL OF PHYSIOLOGICAL SCIENCES, 59 465-465, 2009
ENLARGEMENT AND SHRINKAGE OF DENDRITIC SPINES WITH TWO-PHOTON UNCAGING OF IDENTIFIED SPINES

Tatsuya Hayama, Jun-ichi Tanaka, Masanori Matsuzaki, Takashi Miyazaki, Graham C. R. Ellis-Davies, Haruo Kasai

JOURNAL OF PHYSIOLOGICAL SCIENCES, 59 464-464, 2009
Transcranial optogenetic stimulation for mapping of the motor cortex

Riichiro Hira, Fuki Okubo, Naoki Honkura, Jun Noguchi, Yoshio Maruyama, George J. Augustine, Haruo Kasai, Masanori Matsuzaki

NEUROSCIENCE RESEARCH, 65 S201-S201, 2009
Exploration of two-photon photostimulation for neuroscience

Haruo Kasai, Yuya Kanemoto, Masanori Matsuzaki, Graham Ellis-Davis, Atsuya Momotake, Tatsurou Arai, Klaus Hahn, Yi Wu, Motoko Ishikawa, Jun Noguchi …

NEUROSCIENCE RESEARCH, 65 S3-S3, 2009
Principles of long-term dynamics of dendritic spines

Nobuaki Yaumatsu, Masanori Matsuzaki, Takashi Miyazaki, Jun Noguchi, Haruo Kasai

NEUROSCIENCE RESEARCH, 61 S80-S80, 2008
Structural plasticity of dendritic spines induced by two-photon stimulation

Tatsuya Hayama, Masanori Matsuzaki, Graham C. R. Ellis-Davies, Yoshinori Fujiyoshi, Haruo Kasai

NEUROSCIENCE RESEARCH, 61 S143-S143, 2008
Protein-synthesis and neurotrophin dependent structural plasticity of single dendritic spines

Yoshihiro Horiike, Jun-ichi Tanake, Masanori Matsuzaki, Takashi Miyazaki, Graham C. R. Ellis-Davies, Haruo Kasai

NEUROSCIENCE RESEARCH, 61 S68-S68, 2008
Two-photon excitation microscopy

Cell technology., 26(3) 298-302, Mar, 2007

Research Projects

行動変容を創発する脳ダイナミクスの解読と操作が拓く多元生物学

科学研究費助成事業, 学術変革領域研究(A), 日本学術振興会, Jun, 2022 - Mar, 2027

松崎政紀, 尾藤晴彦, 田中康裕, 春野雅彦, 喜多村和郎, 中江健, 井上謙一
全脳運動適応回路の解明

科学研究費助成事業, 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2022 - Mar, 2024

松崎政紀
身体拡張を手掛かりとした自己意識の脳内機構解析

科学研究費助成事業, 基盤研究(A), 日本学術振興会, Apr, 2019 - Mar, 2024

神作憲司, 松崎政紀, 川瀬利弘, 藤木聡一朗
運動学習を実現する広域脳ネットワーク回路可塑性の包括的研究

科学研究費助成事業, 基盤研究(A), 日本学術振興会, Apr, 2019 - Mar, 2023

松崎政紀
Brain information dynamics

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Jun, 2017 - Mar, 2022

MATSUZAKI Masanori
Brain information dynamics underlying multi-area interconnectivity and parallel processing

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Jun, 2017 - Mar, 2022
大脳メタ記憶神経回路の解明：光遺伝学による内省の因果的制御

科学研究費助成事業, 基盤研究(S), 日本学術振興会, May, 2017 - Mar, 2022

宮下保司, 内山安男, 松崎政紀, 小西清貴, 大木研一
Study of motor cortical circuits for motor learning

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2019

MATSUZAKI Masanori
大脳－小脳運動適応多層回路の解明

科学研究費助成事業, 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2017 - Mar, 2018

松崎政紀
文脈依存的な行動シフトを実現する脳神経回路の機能遷移の解明

科学研究費助成事業, 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2017 - Mar, 2018

松崎政紀
文脈依存的な行動シフトを実現する大脳皮質運動回路の解明

科学研究費助成事業, 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2015 - Mar, 2017

松崎政紀
Comprehensive Brain Science Network

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Apr, 2010 - Mar, 2016

Kimura Minoru, Tanji Jun, Takada Masahiko, Nakamura Katsuki, Ohtsuka Toshihisa, Aoki Shigeki, Takao Hidemasa, Shimoji Keigo, Goto Masami, Yoshiura Takashi, Nakata Yasuhiro, Abe Osamu, Masumoto Tomohiko, Tokumaru Aya, Matsumura Akira, Kirino Eiji, Terada Hitoshi, Sato Noriko, Kasai Kiyoto, Hashimoto Ryota, Niwa Shin-ichi, Kato Tadafumi, Suzuki Michio, Shuji Iritani, Nemoto Kiyotaka, Tomita Hiroaki, Murayama Shigeo, Akatsu Hiroyasu, Takao Masaki, Saito Yuko, Bito Haruhiko, Yoshimura Yumiko, Matsuzaki Masanori, Furuta Toshiaki, Okado Haruo, Saito Izumu, Kaibuchi Kozo, Hasegawa Masato, Aiba Atsu, Shiina Nobuyuki, Igarashi Michihiro, Tomoki Nishioka, Watanabe Masahiko, Koike Masato, Sakagami Hiroyuki, Shigemoto Ryuichi, Fukazawa Yugo, Sakimura Kenji, Mori Hisashi, Mishina Masayoshi, Kobayashi Kazuto, Yanagawa Yuchio, Uemura Tadashi, Ishihara Takeshi, Nose Akinao, Iino Yuichi, Miyakawa Tsuyoshi, Takao Keizo, Mushiake Hajime, Katayama Norihiro, Tanaka Tetsu, Inoue Kazuhide, Okabe Shigeo, Kano Masanobu, Fujiyama Fumino, Isa Tadashi, Kageyama Ryoichiro, Fujita Ichiro, Yoshida Akira, Nishikawa Toru, Nukina Nobuyuki, Fukai Tomoki, Iwatsubo Takeshi, Yamamori Tetsuo, Okazawa Hitoshi, Tanaka Keiji, Kakigi Ryusuke, Tsuda Ichiro, Kitazawa Shigeru, Doya Kenji, Takahashi Ryosuke, Ikenaka Kazuhiro, Sobue Gen, Hasegawa Toshikazu, Ota Jun, Saitoe Minoru, Kadomatsu Kenji, Kida Satoshi, Manabe Toshiya, Tomita Taisuke, Iwata Atsushi, Murakami Ikuya, Tsutsui Ken-ichiro, Hanakawa Takashi, Hirai Hirokazu, Mima Tatsuya, Isomura Yoshikazu, Samejima Kazuyuki, Hoshi Eiji, Miyata Mariko, Yuzaki Michisuke, Tanaka Masaki, Fukata Masaki, Suzuki Kyoko, Kuba Hiroshi, Masu Masayuki, Kinoshita Makoto, Sugihara Izumi, Shirane Michiko, Yamamoto Nobuhiko, Nishijo Hisao, Nambu Atsushi, Takumi Toru, Yamashita Toshihide, Sakurai Takeshi, Tamamaki Nobuaki, Hata Yoshio, Harada Akihiro, Ozaki Norio, Sakai Katsuyuki, Kubo Yoshihiro, Nakazawa Takanobu, Tanaka Kenji, Takei Nobuyuki, Hitoshi Seiji, Takahiroa. Kato, Kato Fusao, Shirao Tomoaki, Taira Masato, Okano Hideyuki, Sekino Yuko, Okamoto Yasumasa, KOMATSU Hidehiko, Miyata Takaki, Takahashi Yoshiko, Nishida Shinya, Tominaga Makoto
Mesoscopic neurocircuitry: towards understanding of the functional and structual basis of brain information processing

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Apr, 2010 - Mar, 2016

NOSE AKINAO, IKEGAYA Yuji, UEMURA Tadashi, HOSOYA Toshihiko, MATSUZAKI Masanori, KANEKO Takeshi, YAMAMOTO Nobuhiko, YAMANAKA Akihiro, YOSHIMURA Yumiko, KENGAKU Mineko, IWASATO Takuji, HATA Yoshio, SHIBUKI Katsuei, ISHII Shin, FUKAI Tomoki
Systematic functional mapping of synaptic connections between cerebral cortical areas

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2011 - 2014

MATSUZAKI Masanori, OKADA Takashi
Synaptic integration in mesoscopic circuits in the cerebral cortex

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, 2010 - 2014

MATSUZAKI Masanori
Cerebral spine synapses and exocytosis studied with two-photon microscope

Grants-in-Aid for Scientific Research, Grant-in-Aid for Specially Promoted Research, Japan Society for the Promotion of Science, 2009 - 2014

KASAI Haruo, MATSUZAKI Masanori, TAKAHASHI Noriko, NOGICHI Jun, WATANABE Satoshi
新規の光刺激法による非侵襲・生理的条件下における中枢神経シナプス長期可塑性の研究

科学研究費補助金(特定領域研究), 特定領域研究, 文部科学省, 2008 - 2009

松崎政紀
Study of the function and structure of single inhibitory synapses revealed by two-photon uncaging of GABA

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (A), Japan Society for the Promotion of Science, 2007 - 2009

MATSUZAKI Masanori
2光子励起グルタミン酸活性化法による大脳シナプス構造・機能可塑性の包括的研究

科学研究費補助金(若手研究(A)), 若手研究(A), 文部科学省, 2005 - 2006

松崎政紀
大脳新皮質におけるスパイン形態可塑性の2光子励起グルタミン酸法を用いた研究

科学研究費補助金(特定領域研究), 特定領域研究, 文部科学省, 2005 - 2005

松崎政紀

Industrial Property Rights

WO2017-047243 顕微鏡用光学モジュール、顕微鏡、顕微鏡用光学モジュール制御装置及び多光子励起顕微鏡

松崎政紀, 寺田晋一郎

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Awards

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Misc.

Research Projects

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