2020年6月15日
Risk factors of attacks in neuromyelitis optica spectrum disorders.
Journal of neuroimmunology
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- 巻
- 343
- 号
- 開始ページ
- 577236
- 終了ページ
- 577236
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.jneuroim.2020.577236
Predisposing factors before the onset of neuromyelitis optica spectrum disorders (NMOSD) have not been systematically evaluated by now. We investigated the detailed pre-onset history in consecutive NMOSD patients. Thirteen of the enrolled 53 NMOSD patients (24.5%) had accompanying autoimmune diseases, such as Sjögren's syndrome. History of malignancy was seen in 8 of the 53 patients (15.1%). Recent history of non-neurological clinical episodes, such as systemic allergic reaction, systemic infection, surgical operation, or traumatic injury, was seen in 23 of the 53 patients (43.4%). NMOSD patients are likely to have pre-onset history of other autoimmune diseases, malignancy, or recent non-neurological systemic conditions, which may predispose or trigger the onset of NMOSD.
- リンク情報
- ID情報
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- DOI : 10.1016/j.jneuroim.2020.577236
- PubMed ID : 32279020