論文

査読有り 国際誌
2020年6月15日

Risk factors of attacks in neuromyelitis optica spectrum disorders.

Journal of neuroimmunology
  • Tetsuya Akaishi
  • ,
  • Toshiyuki Takahashi
  • ,
  • Kazuo Fujihara
  • ,
  • Tatsuro Misu
  • ,
  • Michiaki Abe
  • ,
  • Tadashi Ishii
  • ,
  • Masashi Aoki
  • ,
  • Ichiro Nakashima

343
開始ページ
577236
終了ページ
577236
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.jneuroim.2020.577236

Predisposing factors before the onset of neuromyelitis optica spectrum disorders (NMOSD) have not been systematically evaluated by now. We investigated the detailed pre-onset history in consecutive NMOSD patients. Thirteen of the enrolled 53 NMOSD patients (24.5%) had accompanying autoimmune diseases, such as Sjögren's syndrome. History of malignancy was seen in 8 of the 53 patients (15.1%). Recent history of non-neurological clinical episodes, such as systemic allergic reaction, systemic infection, surgical operation, or traumatic injury, was seen in 23 of the 53 patients (43.4%). NMOSD patients are likely to have pre-onset history of other autoimmune diseases, malignancy, or recent non-neurological systemic conditions, which may predispose or trigger the onset of NMOSD.

リンク情報
DOI
https://doi.org/10.1016/j.jneuroim.2020.577236
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32279020
ID情報
  • DOI : 10.1016/j.jneuroim.2020.577236
  • PubMed ID : 32279020

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