masato hasegawa

J-GLOBAL         Last updated: Jan 17, 2019 at 12:07
 
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masato hasegawa

Published Papers

 
The effect of truncation on prion-like properties of α-synuclein.
Terada T, Suzuki G, Nonaka T, Kametani F, Tamaoka A, and Hasegawa M.
J Biol Chem   293 13910-13920   Sep 2018   [Refereed]
C9ORF72 dipeptide repeat poly-GA inclusions promote: intracellular aggregation of phosphorylated TDP-43.
Nonaka T, Masuda-Suzukake M, Hosokawa M, Shimozawa A, Hirai S, Okado, H., Hasegawa, M
Hum Mol Genet,   27(15) 2658-2670   May 2018   [Refereed]
Potent prion-like behaviors of pathogenic α-synuclein and evaluation of inactivation methods.
Tarutani, A, Arai T Murayama, S., Hisanaga, S.I., Hasegawa, M.
Acta Neuropathol Commun   6 29   Apr 2018   [Refereed]
Involvement of Cellular Prion Protein in α-Synuclein Transport in Neurons.
Urrea L, Segura-Feliu M, Masuda-Suzukake M, Hervera A, Pedraz L, Aznar J, Vila M, Samitier J, Torrents E, Ferrer I, Gavín R, Hasegawa M, José Antonio del Río.
Mol Neurobiol   55 1861   Mar 2018   [Refereed]
Isoform-independent and -dependent phosphorylation of microtubule-associated protein tau in mouse brain during postnatal development.
Tuerde D, Kimura T, Miyasaka T, Furusawa K, Shimozawa A, Hasegawa M, Ando K, Hisanaga SI.
J Biol Chem   293 1781-1793   Feb 2018   [Refereed]
Pathological Endogenous α-Synuclein Accumulation in Oligodendrocyte Precursor Cells Potentially Induces Inclusions in Multiple System Atrophy.
Kaji S, Maki T, Kinoshita H, Uemura N, Ayaki T, Kawamoto Y, Furuta T, Urushitani M, Hasegawa M, Kinoshita Y, Ono Y, Mao X, Quach TH, Iwai K, Dawson VL, Dawson TM, Takahashi R.
Stem Cell Rep   10 356-365   Feb 2018   [Refereed]
Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease.
Kametani F and Hasegawa M.
Front Neurosci   12 25   Jan 2018   [Refereed]
Mutations in bassoon in individuals with familial and sporadic progressive supranuclear palsy-like syndrome.
Yabe I, Yaguchi H, Kato Y, Miki Y, Takahashi H, Tanikawa S, Shirai S, Takahashi I, Kimura M, Hama Y, Matsushima M, Fujioka S, Kano T, Watanabe M, Nakagawa S, Kunieda Y, Ikeda Y, Hasegawa M, Nishihara H, Ohtsuka T, Tanaka S, Tsuboi Y, Hatakeyama S, Wakabayashi K, Sasaki H.
Sci Rep   8 819   Jan 2018   [Refereed]
Shimozawa A, Ono M, Takahara D, Tarutani A, Imura S, Masuda-Suzukake M, Higuchi M, Yanai K, Hisanaga SI, Hasegawa M.
Acta Neuropathol Commun.   5((1)) 12.   Feb 2017   [Refereed]
Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes.
Tanaka Y, Suzuki G, Matsuwaki T, Hosokawa M, Serrano G, Beach TG, Yamanouchi K, Hasegawa M, Nishihara M.
Hum Mol Genet   26 969-988   Jan 2017   [Refereed]
α-Synuclein: Experimental pathology.
Hasegawa M, Nonaka T, Masuda-Suzukake M.
Cold Spring Harb Perspect Med   6 305-318   2017   [Refereed]
Prion-like mechanisms and potential therapeutic targets in neurodegenerative disorders.
Hasegawa M, Nonaka T, Masuda-Suzukake M.
Pharmacol Ther   172 22-33   2017   [Refereed]
Following the fate of endocytosed fibrils.
Hasegawa M and Suzuki G.
J Biol Chem   292(32) 13498-13499   2017   [Refereed]
Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer's disease.
Mano T, Nagata K, Nonaka, T, Tarutani A, Imamura T, Hashimoto T, Bannai T, Koshi-Mano K, Tsuchida T, Ohtomo R, Takahashi-Fujigasaki J, Yamashita S, Ohyagi Y, Yamasaki R, Tsuji S, Tamaoka A, Ikeuchi T, Saido TC, Iwatsubo T, Ushijima T, Murayama S, Hasegawa M, Iwata A.
Proc Natl Acad Sci USA   114 E9645-E9654.   2017   [Refereed]
Wild-type monomeric α-synuclein can impair vesicle endocytosis and synaptic fidelity via tubulin polymerization at the calyx of Held.
Eguchi K, Taoufiq Z, Thorn-Seshold O, Trauner D, Hasegawa M, Takahashi T.
J Neurosci   37 6043-6052   2017   [Refereed]
Accumulation of multiple neurodegenerative disease-related proteins in familial frontotemporal lobar degeneration associated with granulin mutation.
Hosokawa M, Kondo H, Serrano GE, Beach TG, Robinson AC, Mann DM, Akiyama H, Hasegawa M, Arai T.
Sci Rep   7 1513   2017   [Refereed]
Tarutani A, Suzuki G, Shimozawa A, Nonaka T, Akiyama H, Hisanaga S, and Hasegawa M.
J Biol Chem   291 18675-88   Sep 2016   [Refereed]
Oikawa T, Nonaka T, Terada M, Tamaoka A, Hisanaga S, Hasegawa M.
J Biol Chem   291 15046-56   Jul 2016   [Refereed]
Tanaka Y, Nonaka T, Suzuki G, Kametani F, Hasegawa M.
Hum Mol Genet   25 1420-33   Apr 2016   [Refereed]
Shimonaka S, Nonaka T, Suzuki G, Hisanaga SI, Hasegawa M.
J Biol Chem   291 8896-907   Apr 2016   [Refereed]
Nonaka T, Suzuki G, Tanaka Y, Kametani F, Hirai S, Okado H, Miyashita T, Saitoe M, Akiyama H, Masai H, Hasegawa M.
J Biol Chem   291 5473-83   Mar 2016   [Refereed]
Kametani F, Obi T, Shishido T, Akatsu H, Murayama S, Saito Y, Yoshida M, & Hasegawa M.
Sci Rep   6 23281   Mar 2016   [Refereed]
Taniguchi‑Watanabe S, Arai T, Kametani F, Nonaka T, Masuda‑Suzukake M, Tarutani A, Murayama S, Saito Y, Arima K, Yoshida M. Akiyama H, Robinson A, Mann D, Iwatsubo T, Hasegawa M.
Acta Neuropathol   131 267-80   2016   [Refereed]
Molecular Mechanisms in the Pathogenesis of Alzheimer's disease and Tauopathies-Prion-Like Seeded Aggregation and Phosphorylation.
Hasegawa M
Biomolecules   6    2016   [Refereed]
Hasegawa M, Nonaka T, Masuda-Suzukake M.
Pharmacol Ther   30236-4   2016   [Refereed]
Takahashi M, Miyata H, Kametani F, Nonaka T, Akiyama H, Hisanaga S, Hasegawa M.
Acta Neuropathol   29 895-907   2015   [Refereed]
Matsumoto SE, Motoi Y, Ishiguro K, Tabira T, Kametani F, Hasegawa M, Hattori N.
Hum Mol Genet   24 6403-16   2015   [Refereed]
Hosokawa M, Arai T, Masuda-Suzukake M, Kondo H, Matsuwaki T, Nishihara M, Hasegawa M, Akiyama H.
J Neuropathol Exp Neurol   74 158-65   2015   [Refereed]
Baborie A, Griffiths TD, Jaros E, Perry R, McKeith IG, Burn DJ, Masuda-Suzukake M, Hasegawa M, Rollinson S, Pickering-Brown S, Robinson AC, Davidson YS, Mann DM.
Neuropathol Appl Neurobiol   41 601-12   2015   [Refereed]
Masuda-Suzukake M, Nonaka T, Hosokawa M, Kubo M, Shimozawa A, Akiyama H, Hasegawa M.
Acta Neuropathol Commun   2 88   2014   [Refereed]
Yamashita M, Nonaka T, Hirai S, Miwa A, Okado H, Arai T, Hosokawa M, Akiyama H, Hasegawa M.
Hum Mol Genet   23 4345-56   2014   [Refereed]
Hasegawa M, Watanabe S, Kondo H, Akiyama H, Mann DM, Saito Y, Murayama S.
Acta Neuropathol   127 303-305   2014   [Refereed]
Kobayashi Z, Tsuchiya K, Arai T, Aoki M, Hasegawa M, Ishizu H, Akiyama H, Mizusawa H
Journal of the neurological sciences   293(1-2) 6-11   Apr 2010   [Refereed]
Yamaguchi Y, Masuda M, Sasakawa H, Nonaka T, Hanashima S, Hisanaga S, Kato K, Hasegawa M
Journal of molecular biology   395(3) 445-456   Jan 2010   [Refereed]
Arai T, Hasegawa M, Nonoka T, Kametani F, Yamashita M, Hosokawa M, Niizato K, Tsuchiya K, Kobayashi Z, Ikeda K, Yoshida M, Onaya M, Fujishiro H, Akiyama H
Neuropathology : official journal of the Japanese Society of Neuropathology      Jan 2010   [Refereed]
Tamaoka A, Arai M, Itokawa M, Arai T, Hasegawa M, Tsuchiya K, Takuma H, Tsuji H, Ishii A, Watanabe M, Takahashi Y, Goto J, Tsuji S, Akiyama H
Internal medicine (Tokyo, Japan)   49(4) 331-334   2010   [Refereed]
Hasegawa M, Nonaka T, Yamashita M, Kametani F, Arai T, Yoshida M, Hashizume Y, Tsuchiya K, Akiyama H
Rinsho shinkeigaku = Clinical neurology   49(11) 783-785   Nov 2009   [Refereed]
[The molecular mechanisms of intracellular TDP-43 aggregates]
Nonaka T, Arai T, Hasegawa M
Brain and nerve = Shinkei kenkyu no shinpo   61 1292-1300   Nov 2009   [Refereed]
Foulds PG, Davidson Y, Mishra M, Hobson DJ, Humphreys KM, Taylor M, Johnson N, Weintraub S, Akiyama H, Arai T, Hasegawa M, Bigio EH, Benson FE, Allsop D, Mann DM
Acta neuropathologica   118 647-658   Nov 2009   [Refereed]
Nonaka T, Kametani F, Arai T, Akiyama H, Hasegawa M
Human molecular genetics   18 3353-3364   Sep 2009   [Refereed]
Davidson Y, Amin H, Kelley T, Shi J, Tian J, Kumaran R, Lashley T, Lees AJ, DuPlessis D, Neary D, Snowden J, Akiyama H, Arai T, Hasegawa M, Bandopadhyay R, Sikkink S, Pickering-Brown S, Mann DM
Acta neuropathologica   118 359-369   Sep 2009   [Refereed]
Nonaka T, Hasegawa M
Biochemistry   48(33) 8014-8022   Aug 2009   [Refereed]
Schwab C, Arai T, Hasegawa M, Akiyama H, Yu S, McGeer PL
Acta neuropathologica   118 303-311   Aug 2009   [Refereed]
Yamashita M, Nonaka T, Arai T, Kametani F, Buchman VL, Ninkina N, Bachurin SO, Akiyama H, Goedert M, Hasegawa M
FEBS letters   583(14) 2419-2424   Jul 2009   [Refereed]
Yotsumoto K, Saito T, Asada A, Oikawa T, Kimura T, Uchida C, Ishiguro K, Uchida T, Hasegawa M, Hisanaga S
The Journal of biological chemistry   284(25) 16840-16847   Jun 2009   [Refereed]
Kametani F, Nonaka T, Suzuki T, Arai T, Dohmae N, Akiyama H, Hasegawa M
Biochemical and biophysical research communications   382(2) 405-409   May 2009   [Refereed]
Yonetani M, Nonaka T, Masuda M, Inukai Y, Oikawa T, Hisanaga S, Hasegawa M
The Journal of biological chemistry   284(12) 7940-7950   Mar 2009   [Refereed]
Masuda M, Hasegawa M, Nonaka T, Oikawa T, Yonetani M, Yamaguchi Y, Kato K, Hisanaga S, Goedert M
FEBS letters   583(4) 787-791   Feb 2009   [Refereed]
[Neurodegenerative disorders and TDP-43]
Nonaka T, Inukai Y, Arai T, Hasegawa M
Brain and nerve = Shinkei kenkyu no shinpo   61 161-166   Feb 2009   [Refereed]
Arai T, Mackenzie IR, Hasegawa M, Nonoka T, Niizato K, Tsuchiya K, Iritani S, Onaya M, Akiyama H
Acta neuropathologica   117 125-136   Feb 2009   [Refereed]

Books etc

 
TDP-43 prions.
Nonaka T and Hasegawa M. (Part:Contributor, Cold Spring Harb Perspect Med, Chapter 41)
Cold Spring Harbor Laboratory Press   Jan 2017   
α-Synuclein: Experimental pathology.
Hasegawa M, Nonaka T, Masuda-Suzukake M. (Part:Contributor, Cold Spring Harb Perspect Med 6(9).)
Cold Spring Harbor Laboratory Press   2016   
Molecular Biology of Dementia with Lewy Bodies,
Hasegawa M (Part:Contributor, Dementia with Lewy Bodies, Chapter 4: P41-58,)
Springer, Edited by Kenji Kosaka.   2016