論文

2017年1月

Characteristics of spinopelvic alignment in Parkinson's disease: Comparison with adult spinal deformity.

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
  • Kei Watanabe
  • Toru Hirano
  • Keiichi Katsumi
  • Masayuki Ohashi
  • Hirokazu Shoji
  • Kazuhiro Hasegawa
  • Akiyoshi Yamazaki
  • Atsushi Ishikawa
  • Ryoko Koike
  • Naoto Endo
  • Masatoyo Nishizawa
  • Takayoshi Shimohata
  • 全て表示

22
1
開始ページ
16
終了ページ
21
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.jos.2016.09.013

PURPOSE: The characteristics and pathogenesis of spinopelvic alignment in Parkinsons's disease (PD) patients-including differences compared to non-PD subjects and their relationships with the severity of PD-have not been clarified. The aim of this study was to investigate the characteristics of spinopelvic alignment in patients with PD. METHODS: Forty-eight PD patients complaining of chronic low back pain were included (PD group). The PD condition, determined using the Hoehn and Yahr (H&Y) stage and Unified Parkinson Disease Rating Scale (UPDRS) score; radiographic spinopelvic alignment; lumbar range of motion (ROM); and low back pain-related quality of life assessments were evaluated. Fifty age- and sex-matched patients with adult spinal deformities were included as controls (ASD group). RESULTS: The spinopelvic alignments of the PD/ASD groups demonstrated sagittal vertical axes of 120.9/106.3 mm and pelvic incidences of 49.7/52.9°, with no significant differences. Conversely, there were significant differences in the thoracic kyphosis (TK; 27.6/16.7°), lumbar lordosis (-22.7/-7.9°), and pelvic tilt (25.3/34.4°) (all, p < 0.05). With regard to correlations with the PD condition, the H&Y stage demonstrated significant correlations with the sagittal vertical axis, thoracolumbar kyphosis, and lumbar ROM (all, p < 0.05), and the UPDRS score tended to correlate with the TK and thoracolumbar kyphosis (both, p < 0.01). CONCLUSION: Characteristic spinal conditions in PD exist, with progressed PD condition causing stooped posture with increased thoracic or thoracolumbar kyphosis and decreased lumbar ROM; moreover, global sagittal malalignment progresses without sufficient compensatory mechanisms such as loss of TK and pelvic retroversion.

リンク情報
DOI
https://doi.org/10.1016/j.jos.2016.09.013
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/27964875
ID情報
  • DOI : 10.1016/j.jos.2016.09.013
  • PubMed ID : 27964875

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