論文

査読有り 国際誌
2020年6月30日

Connectivity Gradient in the Human Left Inferior Frontal Gyrus: Intraoperative Cortico-Cortical Evoked Potential Study.

Cerebral cortex (New York, N.Y. : 1991)
  • Takuro Nakae
  • ,
  • Riki Matsumoto
  • ,
  • Takeharu Kunieda
  • ,
  • Yoshiki Arakawa
  • ,
  • Katsuya Kobayashi
  • ,
  • Akihiro Shimotake
  • ,
  • Yukihiro Yamao
  • ,
  • Takayuki Kikuchi
  • ,
  • Toshihiko Aso
  • ,
  • Masao Matsuhashi
  • ,
  • Kazumichi Yoshida
  • ,
  • Akio Ikeda
  • ,
  • Ryosuke Takahashi
  • ,
  • Matthew A Lambon Ralph
  • ,
  • Susumu Miyamoto

30
8
開始ページ
4633
終了ページ
4650
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1093/cercor/bhaa065

In the dual-stream model of language processing, the exact connectivity of the ventral stream to the anterior temporal lobe remains elusive. To investigate the connectivity between the inferior frontal gyrus (IFG) and the lateral part of the temporal and parietal lobes, we integrated spatiotemporal profiles of cortico-cortical evoked potentials (CCEPs) recorded intraoperatively in 14 patients who had undergone surgical resection for a brain tumor or epileptic focus. Four-dimensional visualization of the combined CCEP data showed that the pars opercularis (Broca's area) is connected to the posterior temporal cortices and the supramarginal gyrus, whereas the pars orbitalis is connected to the anterior lateral temporal cortices and angular gyrus. Quantitative topographical analysis of CCEP connectivity confirmed an anterior-posterior gradient of connectivity from IFG stimulus sites to the temporal response sites. Reciprocality analysis indicated that the anterior part of the IFG is bidirectionally connected to the temporal or parietal area. This study shows that each IFG subdivision has different connectivity to the temporal lobe with an anterior-posterior gradient and supports the classical connectivity concept of Dejerine; that is, the frontal lobe is connected to the temporal lobe through the arcuate fasciculus and also a double fan-shaped structure anchored at the limen insulae.

リンク情報
DOI
https://doi.org/10.1093/cercor/bhaa065
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32232373
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325718
ID情報
  • DOI : 10.1093/cercor/bhaa065
  • PubMed ID : 32232373
  • PubMed Central 記事ID : PMC7325718

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