Riki Matsumoto

J-GLOBAL         Last updated: Aug 18, 2019 at 16:25
 
Avatar
Name
Riki Matsumoto
E-mail
matsumotmed.kobe-u.ac.jp
Affiliation
Kobe University
Section
Neurology
Degree
M.D., Ph.D.

Research Interests

 
 

Research Areas

 

Academic & Professional Experience

 
Dec 2018
 - 
Today
Professor, Division of Neurology, Kobe University Graduate School of Medicine
 
Aug 2016
 - 
Nov 2018
Associate Professor, Department of Neurology, Graduate School of Medicine, Kyoto University
 
Aug 2013
 - 
Jul 2016
Associate Professor, Department of Epilepsy, Movement Disorder and Physiology, Kyoto University Graduate School of Medicine
 
Aug 2012
 - 
Jul 2013
Senior Lecturer, Department of Neurology, Kyoto University Graduate School of Medicine
 
Jun 2011
 - 
Jul 2012
Senior Lecturer, Department of Neurology, Kyoto University Hospital
 
Apr 2007
 - 
May 2011
Assistant Professor, Department of Neurology, Kyoto University Hospital
 
Apr 2006
 - 
Mar 2007
Section Head, Department of Neurology, National Health Organization Utano Hospital
 
Jul 2002
 - 
Mar 2006
Clinical Fellow, Department of Neurology, Kyoto University Hospital
 
Jul 2000
 - 
Jun 2002
Clinical Fellow, Section of Epilepsy and Clinical Neurophysiology, Department of Neurology, The Cleveland Clinic Foundation
 

Awards & Honors

 
Apr 2016
Japan Epilepsy Research Foundation Research Award 2016, Japan Epilepsy Research Foundation
Winner: Riki Matsumoto, Kunieda Takeharu
 
Jun 2015
Human Brain Mapping Editor's Choice Award 2014, The Organization for Human Brain Mapping
Winner: Riki Matsumoto, Takeharu Kunieda, Yukihiro Yamao, et al.
 
May 2015
Excellent Teacher 2015, Japanse Society of Neurology
 
Nov 2014
4th Encouragement Award, Japanese Society of Clinical Neurophysiology
 
Oct 2005
28th JUHN AND MARY WADA AWARD, Japan Epilepsy Society
 

Published Papers

 
Please see MISC section for publications
(b/o DL problems from Scopus/MISC
   Aug 2019   [Refereed]

Misc

 
Kazuki Oi, Shuichiro Neshige, Takefumi Hitomi, Katsuya Kobayashi, Maya Tojima, M. Matsuhashi, Akihiro Shimotake, D. Fujii, Riki Matsumoto, Shuhei Kasama, Masutaro Kanda, Yoshiaki Wada, Hirofumi Maruyama, Ryosuke Takahashi, Akio Ikeda
Clinical Neurophysiology   130 1804-1812   Oct 2019
© 2019 International Federation of Clinical Neurophysiology Objective: To elucidate the effects of perampanel (PER) on refractory cortical myoclonus for dose, etiology and somatosensory-evoked potential (SEP) findings. Methods: We examined 18 epil...
Kiyohide Usami, Anna Korzeniewska, Riki Matsumoto, Katsuya Kobayashi, Takefumi Hitomi, Masao Matsuhashi, Takeharu Kunieda, Nobuhiro Mikuni, Takayuki Kikuchi, Kazumichi Yoshida, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda, Nathan E. Crone
Sleep   42    Jun 2019
© Sleep Research Society 2019. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com. Wakefulness and sleep arise from global changes in brain...
Hans Lüders, Naoki Akamatsu, Shahram Amina, Christoph Baumgartner, Selim Benbadis, Adriana Bermeo-Ovalle, Andrew Bleasel, Alireza Bozorgi, Mar Carreño, Michael Devereaux, Guadalupe Fernandez-Baca Vaca, Stefano Francione, Naiara García Losarcos, Hajo Hamer, Hans Holthausen, Shirin Jamal Omidi, Giridhar Kalamangalam, Andrés Kanner, Susanne Knake, Nuria Lacuey, Samden Lhatoo, Shih Hui Lim, Jayanthi Mani, Riki Matsumoto, Jonathan Miller, Soheyl Noachtar, André Palmini, Jun Park, Felix Rosenow, Asim Shahid, Stephan Schuele, Bernhard Steinhoff, Charles Ákos Szabo, Nitin Tandon, Kiyohito Terada, Walter Van Emde Boas, Peter Widdess-Walsh, Philippe Kahane
Epilepsia   60 1032-1039   Jun 2019
Wiley Periodicals, Inc. © 2019 International League Against Epilepsy This article critiques the International League Against Epilepsy (ILAE) 2015-2017 classifications of epilepsy, epileptic seizures, and status epilepticus. It points out the follo...
Shuichiro Neshige, Katsuya Kobayashi, Masao Matsuhashi, Takefumi Hitomi, Akihiro Shimotake, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Riki Matsumoto, Susumu Miyamoto, Ryosuke Takahashi, Hirofumi Maruyama, Akio Ikeda
Epilepsia   60 547-559   Mar 2019
Wiley Periodicals, Inc. © 2019 International League Against Epilepsy Objective: For future artificial intelligence–based brain mapping, development of a rational and safe scoring system for a brain motor mapping algorithm using electrocorticograph...
Takeshi Inoue, Morito Inouchi, Masao Matsuhashi, Riki Matsumoto, Takefumi Hitomi, Masako Daifu-Kobayashi, Katsuya Kobayashi, Mitsuyoshi Nakatani, Kyoko Kanazawa, Akihiro Shimotake, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society   36 166-170   Mar 2019
PURPOSE: We reported the presence of interictal slow and high-frequency oscillations (HFOs) (IIS + HFO) and its temporal change so as to elucidate its clinical usefulness as a surrogate marker of epileptogenic zone in a patient with intractable fo...
Hans Lüders, Guadalupe Fernandez Baca Vaca, Naoki Akamatsu, Shahram Amina, Alexis Arzimanoglou, Christoph Baumgartner, Selim R. Benbadis, Andrew Bleasel, Adriana Bermeo-Ovalle, Alireza Bozorgi, Mar Carreño, Michael Devereaux, Stefano Francione, Naiara García Losarcos, Hajo Hamer, Hans Holthausen, Shirin Jamal-Omidi, Giri Kalamangalam, Andrés M. Kanner, Susanne Knake, Nuria Lacuey, Samden Lhatoo, Shih Hui Lim, Luisa V. Londoño, Jayanti Mani, Riki Matsumoto, Jonathan P. Miller, Soheyl Noachtar, André Palmini, Jun Park, Felix Rosenow, Asim Shahid, Stephan Schuele, Bernhard J. Steinhoff, Charles Ákos Szabó, Nitin Tandon, Kiyohito Terada, Walter van Emde Boas, Peter Widdess-Walsh, Philippe Kahane
Epileptic Disorders   21 1-29   Feb 2019
© 2019 Epileptic Disorders This educational review describes the classification of paroxysmal events and a four-dimensional epilepsy classification system. Paroxysmal events are classified as epileptic and non-epileptic paroxysmal events. Non-epil...
Takefumi Hitomi, Morito Inouchi, Hirofumi Takeyama, Katsuya Kobayashi, Shamima Sultana, Takeshi Inoue, Yuko Nakayama, Akihiro Shimotake, Masao Matsuhashi, Riki Matsumoto, Kazuo Chin, Ryosuke Takahashi, Akio Ikeda
Epilepsy and Behavior Case Reports   11 18-21   Jan 2019
© 2018 The Authors To clarify the effects of sleep on cortical irritability in benign adult familial myoclonus epilepsy (BAFME), we retrospectively compared epileptiform discharges of electroencephalographies (EEGs) between awake and sleep periods...
Masahiro Nagano, Katsuya Kobayashi, Mayumi Yamada-Otani, Akira Kuzuya, Riki Matsumoto, Jiro Oita, Makoto Yoneda, Akio Ikeda, Ryosuke Takahashi
Internal Medicine   58 1167-1172   Jan 2019
© 2019 The Japanese Society of Internal Medicine. Hashimoto’s encephalopathy (HE) is a steroid-responsive autoimmune encephalopathy associated with Hashimoto thyroiditis. We herein report a case of HE manifesting “smoldering” limbic encephalitis w...
Shuichiro Neshige, Riki Matsumoto, Morito Inouchi, Katsuya Kobayashi, Akihiro Shimotake, Hirofumi Maruyama, Ryosuke Takahashi, Akio Ikeda
Internal Medicine   58 1151-1155   Jan 2019
© 2019 The Japanese Society of Internal Medicine. We herein report two epilepsy patients with the seizure focus in the non-dominant hemisphere manifesting secondarily generalized convulsion (sGC) with retained awareness characterized by a lack of ...
Riki Matsumoto, Takayuki Kikuchi, Yukihiro Yamao, Takuro Nakae, Katsuya Kobayashi, Akihiro Shimotake, Kazumichi Yoshida, Takeharu Kunieda, Akio Ikeda, Susumu Miyamoto
Japanese Journal of Neurosurgery   28 316-325   Jan 2019
© 2019, Japanese Congress of Neurological Surgeons. All rights reserved. Epilepsy can be treated with antiepileptic drugs in 60%-70% of affected patients. However, the remaining 30%-40% of patients with epilepsy become medically intractable. For p...
Aya Kanno, Rei Enatsu, Satoshi Ookawa, Shouhei Noshiro, Shunya Ohtaki, Kengo Suzuki, Yuto Suzuki, Rintaro Yokoyama, Satoko Ochi, Yukinori Akiyama, Takeshi Mikami, Takuro Nakae, Takayuki Kikuchi, Takeharu Kunieda, Susumu Miyamoto, Riki Matsumoto, Nobuhiro Mikuni
World Neurosurgery   120    Dec 2018
© 2018 Background: The connection between the ventrolateral frontal and temporoparietal cortices has an important role in language function on the language-dominant side and spatial awareness on the nondominant side. However, the laterality of the...
Katsuya Kobayashi, Takefumi Hitomi, Riki Matsumoto, Masako Watanabe, Ryosuke Takahashi, Akio Ikeda
Seizure   61 14-22   Oct 2018
© 2018 British Epilepsy Association Purpose: Benign adult familial myoclonus epilepsy (BAFME) is an autosomal dominant disease representing tremulous myoclonus or cortical tremor and infrequent generalized seizures. We aimed to delineate detailed ...
Hajime Yoshimura, Riki Matsumoto, Hiroyuki Ueda, Koichi Ariyoshi, Akio Ikeda, Ryosuke Takahashi, Nobuo Kohara
Seizure   61 23-29   Oct 2018
© 2018 British Epilepsy Association Purpose: Previous studies on status epilepticus (SE) in the elderly were conducted in tertiary centers. We aimed to delineate the features and outcomes of elderly SE patients by comparing them to those of younge...
Shuichiro Neshige, Masao Matsuhashi, Katsuya Kobayashi, Takeyo Sakurai, Akihiro Shimotake, Takefumi Hitomi, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Riki Matsumoto, Ryosuke Takahashi, Susumu Miyamoto, Hirofumi Maruyama, Masayasu Matsumoto, Akio Ikeda
Clinical Neurophysiology   129 2038-2048   Sep 2018
© 2018 International Federation of Clinical Neurophysiology Objective: To assess the feasibility of multi-component electrocorticography (ECoG)-based mapping using “wide-spectrum, intrinsic-brain activities” for identifying the primary sensori-mot...
Tomoyuki Fumuro, Masao Matsuhashi, Riki Matsumoto, Kiyohide Usami, Akihiro Shimotake, Takeharu Kunieda, Takayuki Kikuchi, Kazumichi Yoshida, Ryosuke Takahashi, Susumu Miyamoto, Akio Ikeda
Clinical Neurophysiology   129 1884-1890   Sep 2018
© 2018 International Federation of Clinical Neurophysiology Objective: Neuro-feedback (NFB) training by the self-regulation of slow potentials (SPs) <0.5 Hz recorded from the vertex scalp has been applied for seizure suppression in patients with e...
Kosuke Tanioka, Takefumi Hitomi, Kazuaki Sato, Shuichiro Neshige, Takeshi Tsukada, Daiki Fujii, Takeshi Inoue, Hajime Yoshimura, Katsuya Kobayashi, Akihiro Shimotake, Riki Matsumoto, Ryosuke Takahashi, Akio Ikeda
Journal of the Japan Epilepsy Society   35 684-692   Jan 2018
To clarify the current situation of regional epilepsy care and its dissociation from the regional cooperative model for comprehensive epilepsy care, we retrospectively investigated the consecutive sample survey of epilepsy clinic of 1 certified ep...
Shunsuke Kajikawa, Katsuya Kobayashi, Kiyohide Usami, Riki Matsumoto, Akio Ikeda, Ryosuke Takahashi
Clinical Neurology   58 513-516   Jan 2018
© 2018 Societas Neurologica Japonica. All rights reserved. Promnesia is a feeling of familiarity and foreknowledge and is a manifestation of simple partial seizures (focal aware seizures). It is similar to déjà vu and has been reported to be a rar...
Shinako Inaida, Kousuke Kanemoto, Shiro Tanaka, Yoko Gouji, Tomohiro Oshima, Riki Matsumoto, Akio Ikeda, Koji Kawakami
Epilepsy and Seizure   10 73-86   Jan 2018
© 2018, Japan Epilepsy Society. All rights reserved. Purpose: Psychogenic non-epileptic seizures (PNES) are psychogenic disorders that often resemble epileptic seizures. Herein, we describe the recent clinical trends of PNES by using the data from...
Yuki Oi, Katsuya Kobayashi, Takefumi Hitomi, Riki Matsumoto, Akio Ikeda, Ryosuke Takahashi
Clinical Neurology   58 622-625   Jan 2018
© 2018 Societas Neurologica Japonica. All rights reserved. We report a 32-year-old female who presented myoclonus and generalized tonic-clonic seizure since she was 9 year-old. Thereafter, she was diagnosed as Unverricht-Lundborg disease by gene a...
Mitsuhiro Sakamoto, Riki Matsumoto, Jumpei Togawa, Yuichiro Hashi, Hirofumi Takeyama, Katsuya Kobayashi, Akihiro Shimotake, Takayuki Kondo, Ryosuke Takahashi, Akio Ikeda
Clinical Neurology   58 609-616   Jan 2018
© 2018 Societas Neurologica Japonica. All rights reserved. The epilepsy syndrome of autoimmune etiology, namely, autoimmune epilepsy has attracted attention in recent years, as was reflected in the new etiology of “immunity” in the Epilepsy Classi...
Masaya Togo, Takefumi Hitomi, Tomohiko Murai, Hajime Yoshimura, Masao Matsuhashi, Riki Matsumoto, Michi Kawamoto, Nobuo Kohara, Ryosuke Takahashi, Akio Ikeda
Journal of Clinical Neurophysiology   35 496-503   Jan 2018
© 2018 by the American Clinical Neurophysiology Society Objective: Slow wave with frequency,0.5 Hz are recorded in various situations such as normal sleep, epileptic seizures. However, its clinical significance has not been fully clarified. Althou...
Jun Ueda, Michi Kawamoto, Ryota Hikiami, Junko Ishii, Hajime Yoshimura, Riki Matsumoto, Nobuo Kohara
Epileptic Disorders   19 465-470   Dec 2017
© 2017 Epileptic Disorders Anti-NMDA receptor encephalitis is a paraneoplastic encephalitis characterised by psychiatric features, involuntary movement, and autonomic instability. Various EEG findings in patients with anti-NMDA receptor encephalit...
Satoshi Ookawa, Rei Enatsu, Aya Kanno, Satoko Ochi, Yukinori Akiyama, Tamaki Kobayashi, Yukihiro Yamao, Takayuki Kikuchi, Riki Matsumoto, Takeharu Kunieda, Nobuhiro Mikuni
World Neurosurgery   107 239-248   Nov 2017
© 2017 Elsevier Inc. Background The frontal aslant tract is a deep frontal pathway connecting the superior frontal gyrus (SFG) to Broca area. This fiber is assumed to be associated with language functions, especially speech initiation and spontane...
Ghee Wan Tan, Takayuki Kondo, Nagahisa Murakami, Keiko Imamura, Takako Enami, Kayoko Tsukita, Ran Shibukawa, Misato Funayama, Riki Matsumoto, Akio Ikeda, Ryosuke Takahashi, Haruhisa Inoue
Stem Cell Research   24 12-15   Oct 2017
© 2017 The Authors Autosomal dominant lateral temporal epilepsy (ADLTE) is an inherited epileptic syndrome, and it is associated with mutations of leucine-rich glioma inactivated 1 (LGI1) gene. The underlying mechanisms of ADLTE are still unknown,...
Riki Matsumoto, Mitsuhiro Sakamoto, Akio Ikeda
Brain and Nerve   69 1115-1124   Oct 2017
The recent discovery of autoimmune antibodies to the neuronal cell surface membrane and extra- or intra-cellular proteins, such as NMDAR and LGI1, shed light on a proposed new etiology of epilepsy, namely, "autoimmune epilepsy". A large part of th...
Borgil Bayasgalan, Masao Matsuhashi, Tomoyuki Fumuro, Haruhiko Nohira, Naoki Nakano, Koji Iida, Masaya Katagiri, Akihiro Shimotake, Riki Matsumoto, Takayuki Kikuchi, Takeharu Kunieda, Amami Kato, Ryosuke Takahashi, Akio Ikeda
Clinical Neurophysiology   128 1583-1589   Sep 2017
© 2017 International Federation of Clinical Neurophysiology Objective We investigated whether vagus nerve stimulation (VNS) induces a positive shift of slow cortical potentials (SCPs) in patients with >50% seizure reduction (responders) but not in...
Katsuya Kobayashi, Riki Matsumoto, Masao Matsuhashi, Kiyohide Usami, Akihiro Shimotake, Takeharu Kunieda, Takayuki Kikuchi, Kazumichi Yoshida, Nobuhiro Mikuni, Susumu Miyamoto, Hidenao Fukuyama, Ryosuke Takahashi, Akio Ikeda
Clinical Neurophysiology   128 1673-1681   Sep 2017
© 2017 International Federation of Clinical Neurophysiology Objective We aimed to clarify that high frequency activity (HFA) of cortico-cortical evoked potentials (CCEPs), elicited by single pulse electrical stimulation (SPES), reflects cortical e...
Kiyohide Usami, Riki Matsumoto, Katsuya Kobayashi, Takefumi Hitomi, Masao Matsuhashi, Akihiro Shimotake, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Nobuhiro Mikuni, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda
Sleep   40    Aug 2017
Study Objectives: To investigate the changes in cortical neural responses induced by external inputs during phasic rapid eye movement (p-REM) sleep.Methods: Single-pulse electrical stimulation (SPES) was directly applied to the human cortex during...
Sumiya Shibata, Masao Matsuhashi, Takeharu Kunieda, Yukihiro Yamao, Rika Inano, Takayuki Kikuchi, Hisaji Imamura, Shigetoshi Takaya, Riki Matsumoto, Akio Ikeda, Ryosuke Takahashi, Tatsuya Mima, Hidenao Fukuyama, Nobuhiro Mikuni, Susumu Miyamoto
Clinical Neurophysiology   128 734-743   May 2017
© 2017 International Federation of Clinical Neurophysiology Objective We describe temporal spread imaging (TSI) that can identify the spatiotemporal pattern of epileptic activity using Magnetoencephalography (MEG). Methods A three-dimensional grid...
Yukihiro Yamao, Kengo Suzuki, Takeharu Kunieda, Riki Matsumoto, Yoshiki Arakawa, Takuro Nakae, Sei Nishida, Rika Inano, Sumiya Shibata, Akihiro Shimotake, Takayuki Kikuchi, Nobukatsu Sawamoto, Nobuhiro Mikuni, Akio Ikeda, Hidenao Fukuyama, Susumu Miyamoto
Human Brain Mapping   38 1977-1991   Apr 2017
© 2017 Wiley Periodicals, Inc. In order to preserve postoperative language function, we recently proposed a new intraoperative method to monitor the integrity of the dorsal language pathway (arcuate fasciculus; AF) using cortico–cortical evoked po...
Yusuke Fujiwara, Riki Matsumoto, Takuro Nakae, Kiyohide Usami, Masao Matsuhashi, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Susumu Miyamoto, Tatsuya Mima, Akio Ikeda, Rieko Osu
NeuroImage   147 302-313   Feb 2017
© 2016 The Authors The cortical motor areas are activated not only during contralateral limb movements but also during ipsilateral limb movements. Although these ipsilateral activities have been observed in several brain imaging studies, their fun...
Riki Matsumoto, Takeharu Kunieda, Dileep Nair
Seizure   44 27-36   Jan 2017
© 2016 British Epilepsy Association In the last decade, single pulse electrical stimulation (SPES) has been used as an investigational tool in the field of epilepsy surgery. Direct cortical stimulation applied at a frequency of ∼1 Hz can probe cor...
Kosuke Tanioka, Takefumi Hitomi, Riki Matsumoto, Ryosuke Takahashi, Shozo Tobimatsu, Takashi Inuzuka, Jun Ichi Kira, Susumu Kusunoki, Akio Ikeda
Clinical Neurology   57 110-117   Jan 2017
We collected and analyzed the questionnaires from the participants in the annual EEG hands-on (5 times) and the regional EEG seminar (6 times). The board-certified neurologists among participants in the regional EEG seminar were always more than t...
Naoya Mimura, Takeshi Inoue, Akihiro Shimotake, Riki Matsumoto, Akio Ikeda, Ryosuke Takahashi
Clinical Neurology   57 430-435   Jan 2017
We report a 34-year-old woman with eating epilepsy induced not only by eating but also seeing foods made of minced meat. In her early 20s of age, she started having simple partial seizures (SPS) as flashback and epigastric discomfort induced by pa...
Takeharu Kunieda, Takayuki Kikuchi, Kazumichi Yoshida, Riki Matsumoto, Susumu Miyamoto
Japanese Journal of Neurosurgery   26 856-863   Jan 2017
© 2017, Japanese Congress of Neurological Surgeons. All rights reserved. The treatment strategy for epilepsy depends on an accurate diagnosis and precise understanding of the pathophysiology of the disease. The diagnosis of epilepsy itself must be...
Hajime Yoshimura, Riki Matsumoto, Hiroyuki Ueda, Koichi Ariyoshi, Michi Kawamoto, Junko Ishii, Akio Ikeda, Ryosuke Takahashi, Nobuo Kohara
Journal of the Neurological Sciences   370 284-289   Nov 2016
© 2016 Elsevier B.V. Objective To delineate the clinical characteristics and functional outcome of status epilepticus (SE) in elderly people, and elucidate prognostic implications of SE-associated rhythmic and periodic patterns (RPPs) in electroen...
Anthony Ritaccio, Riki Matsumoto, Martha Morrell, Kyousuke Kamada, Mohamad Koubeissi, David Poeppel, Jean Philippe Lachaux, Takufumi Yanagisawa, Masayuki Hirata, Christoph Guger, Gerwin Schalk
Epilepsy and Behavior   62 313   Sep 2016
© 2016 The authors regret the misspelling of an author's name in this article. The author name Takufumi Yanagisawa erroneously appeared as Yakufumi Yanagisawa. The authors would like to apologize for any inconvenience caused.
Y. Chen, A. Shimotake, R. Matsumoto, T. Kunieda, T. Kikuchi, S. Miyamoto, H. Fukuyama, R. Takahashi, A. Ikeda, M. A. Lambon Ralph
Cortex   79 1-13   Jun 2016
© 2016 The Authors. Electrocorticograms (ECoG) provide a unique opportunity to monitor neural activity directly at the cortical surface. Ten patients with subdural electrodes covering ventral and lateral anterior temporal regions (ATL) performed a...
Takefumi Hitomi, Katsuya Kobayashi, Takeyo Sakurai, Sakiho Ueda, Naoto Jingami, Kyoko Kanazawa, Riki Matsumoto, Ryosuke Takahashi, Akio Ikeda
Epileptic Disorders   18 67-72   Mar 2016
© 2016 JLE. Background. Brain dysfunction in Japanese benign adult familial myoclonus epilepsy (BAFME) has not been elucidated. Aim. To clarify diffuse brain dysfunction as indicated by posterior dominant rhythm (PDR) slowing in patients with BAFM...
Yukihiro Yamao, Takeharu Kunieda, Riki Matsumoto
Cortex   75 244-246   Feb 2016
Hisaji Imamura, Riki Matsumoto, Shigetoshi Takaya, Tomokazu Nakagawa, Akihiro Shimotake, Takayuki Kikuchi, Nobukatsu Sawamoto, Takeharu Kunieda, Nobuhiro Mikuni, Susumu Miyamoto, Hidenao Fukuyama, Ryosuke Takahashi, Akio Ikeda
Epilepsy Research   120 65-72   Feb 2016
© 2015 Elsevier B.V. Objectives: To identify the specific change of white matter integrity that occurs in the brain network related to epileptic activity in patients with mesial temporal lobe epilepsy (MTLE). Methods: We recruited 18 patients with...
Yukihiro Yamao, Takeharu Kunieda, Riki Matsumoto
Japanese Journal of Neurosurgery   25 411-420   Jan 2016
© 2016, Japanese Congress of Neurological Surgeons. All rights reserved. The preservation of brain function during and after surgery still poses a challenge for neurosurgeons. High-frequency electrical stimulation techniques have been established ...
Kiyohide Usami, Riki Matsumoto, Nobukatsu Sawamoto, Hiroatsu Murakami, Morito Inouchi, Tomoyuki Fumuro, Akihiro Shimotake, Takeo Kato, Tatsuya Mima, Hiroshi Shirozu, Hiroshi Masuda, Hidenao Fukuyama, Ryosuke Takahashi, Shigeki Kameyama, Akio Ikeda
Epilepsy Research   125 1-9   Jan 2016
© 2016 Elsevier B.V. Objective To investigate the brain networks involved in epileptogenesis/encephalopathy associated with hypothalamic hamartoma (HH) by EEG with functional MRI (EEG-fMRI), and evaluate its efficacy in locating the HH interface i...
Yu Uneno, Akira Yokoyama, Yoshitaka Nishikawa, Taro Funakoshi, Yoshinao Ozaki, Ikuo Aoyama, Kiichiro Baba, Daisuke Yamaguchi, Shuko Morita, Yukiko Mori, Masashi Kanai, Hisanori Kinoshita, Takeshi Inoue, Nobukatsu Sawamoto, Riki Matsumoto, Shigemi Matsumoto, Manabu Muto
Internal Medicine   55 2605-2609   Jan 2016
© 2016 The Japanese Society of Internal Medicine. Paraneoplastic neurological syndromes (PNSs) are rare nervous system dysfunctions in cancer patients, which are primarily observed with small-cell lung cancer, gynecological cancer, and thymoma. We...
Kiyohide Usami, Riki Matsumoto, Katsuya Kobayashi, Takefumi Hitomi, Akihiro Shimotake, Takayuki Kikuchi, Masao Matsuhashi, Takeharu Kunieda, Nobuhiro Mikuni, Susumu Miyamoto, Hidenao Fukuyama, Ryosuke Takahashi, Akio Ikeda
Human Brain Mapping   36 4714-4729   Nov 2015
© 2015 Wiley Periodicals, Inc. Sleep-induced changes in human brain connectivity/excitability and their physiologic basis remain unclear, especially in the frontal lobe. We investigated sleep-induced connectivity and excitability changes in 11 pat...
Anthony Ritaccio, Riki Matsumoto, Martha Morrell, Kyousuke Kamada, Mohamad Koubeissi, David Poeppel, Jean Philippe Lachaux, Yakufumi Yanagisawa, Masayuki Hirata, Christoph Guger, Gerwin Schalk
Epilepsy and Behavior   51 312-320   Oct 2015
© 2015 Elsevier Inc. The Seventh International Workshop on Advances in Electrocorticography (ECoG) convened in Washington, DC, on November 13-14, 2014. Electrocorticography-based research continues to proliferate widely across basic science and cl...
Sumiya Shibata, Takeharu Kunieda, Rika Inano, Masahiro Sawada, Yukihiro Yamao, Takayuki Kikuchi, Riki Matsumoto, Akio Ikeda, Ryosuke Takahashi, Nobuhiro Mikuni, Jun Takahashi, Susumu Miyamoto
World Neurosurgery   84 320-326   Aug 2015
© 2015 Elsevier Inc. Objective To evaluate infective complications with intracranial electroencephalography (EEG) recording so as to lessen them. Methods A database of intracranial monitoring cases with subdural electrodes at Kyoto University Hosp...
Yukihiro Yamao, Riki Matsumoto, Takeharu Kunieda, Yoshiki Arakawa, Takayuki Kikuchi, Sumiya Shibata, Akihiro Shimotake, Hidenao Fukuyama, Akio Ikeda, Susumu Miyamoto
Clinical Neurology and Neurosurgery   134 126-129   Jul 2015
Katsuya Kobayashi, Riki Matsumoto, Masao Matsuhashi, Kiyohide Usami, Akihiro Shimotake, Takeharu Kunieda, Takayuki Kikuchi, Nobuhiro Mikuni, Susumu Miyamoto, Hidenao Fukuyama, Ryosuke Takahashi, Akio Ikeda
PLoS ONE   10    Jun 2015
© 2015 Kobayashi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source a...
Yukihiro Yamao, Riki Matsumoto, Takeharu Kunieda, Sumiya Shibata, Akihiro Shimotake, Takayuki Kikuchi, Takeshi Satow, Nobuhiro Mikuni, Hidenao Fukuyama, Akio Ikeda, Susumu Miyamoto
Cortex   66 134-140   May 2015
© 2014 Elsevier Ltd. Laughter consists of both motor and emotional aspects. The emotional component, known as mirth, is usually associated with the motor component, namely, bilateral facial movements. Previous electrical cortical stimulation (ES) ...
Kyoko Kanazawa, Riki Matsumoto, Hisaji Imamura, Masao Matsuhashi, Takayuki Kikuchi, Takeharu Kunieda, Nobuhiro Mikuni, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda
Clinical Neurophysiology   126 47-59   Jan 2015
© 2014 International Federation of Clinical Neurophysiology. Objective: We assessed the temporal-spatial characteristics of ictal direct current (DC) shifts (or infraslow activity) and high frequency oscillations (HFOs) in 16 patients with intract...
Sachiyo Hashi, Ikuko Yano, Mai Shibata, Satohiro Masuda, Masako Kinoshita, Riki Matsumoto, Akio Ikeda, Ryosuke Takahashi, Kazuo Matsubara
European Journal of Clinical Pharmacology   71 51-58   Jan 2015
© Springer-Verlag 2014. Purpose: Clobazam (CLB) is metabolized by cytochrome P450 (CYP) 3A4 to yield N-desmethylclobazam (N-CLB), which is further inactivated by CYP2C19. The aim of this study was to retrospectively evaluate the relationship betwe...
Tomoyuki Fumuro, Riki Matsumoto, Akihiro Shimotake, Masao Matsuhashi, Morito Inouchi, Shin ichi Urayama, Nobukatsu Sawamoto, Hidenao Fukuyama, Ryosuke Takahashi, Akio Ikeda
Clinical Neurophysiology   126 675-681   Jan 2015
© 2014 International Federation of Clinical Neurophysiology. Objective: The pathophysiological mechanisms of partial reading epilepsy are still unclear. We delineated the spatial-temporal characteristics of reading-induced epileptic spikes and hem...
Tomoyuki Fumuro, Masao Matsuhashi, Tomoko Miyazaki, Morito Inouchi, Takefumi Hitomi, Riki Matsumoto, Ryosuke Takahashi, Hidenao Fukuyama, Akio Ikeda
Clinical Neurophysiology   126 756-762   Jan 2015
© 2014 International Federation of Clinical Neurophysiology. Objective: The symptoms with optic ataxia suggest that simple and visually guided hand movements are controlled by 2 different neural substrates. To assess the differential frequency-cod...
Riki Matsumoto, Nobuhiro Mikuni, Keiko Tanaka, Kiyohide Usami, Kenjiro Fukao, Takeharu Kunieda, Yukitoshi Takahashi, Susumu Miyamoto, Hidenao Fukuyama, Ryosuke Takahashi, Akio Ikeda
Epileptic Disorders   17 89-94   Jan 2015
© 2015, John Libbey Eurotext. All rights reserved. "Formes frustes" of encephalopathy associated with anti-NMDAR antibody have been recently described in cases of chronic epilepsy. We report a young woman with a parietal lesion and anti-NMDAR anti...
Takeharu Kunieda, Yukihiro Yamao, Takayuki Kikuchi, Riki Matsumoto
Neurologia Medico-Chirurgica   55 374-382   Jan 2015
© 2015 by The Japan Neurosurgical Society. All rights reserved. There has been a paradigm shift in the understanding of brain function. The intrinsic architecture of neuronal connections forms a key component of the cortical organization in our br...
Akihiro Shimotake, Riki Matsumoto, Taiji Ueno, Takeharu Kunieda, Satoru Saito, Paul Hoffman, Takayuki Kikuchi, Hidenao Fukuyama, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda, Matthew A. Lambon Ralph
Cerebral Cortex   25 3802-3817   Jan 2015
© The Author 2014. Published by Oxford University Press. Semantic memory is a crucial higher cortical function that codes the meaning of objects and words, and when impaired after neurological damage, patients are leftwith significant disability. ...
Takashi Ayaki, Hidefumi Ito, Hiroko Fukushima, Takeshi Inoue, Takayuki Kondo, Akito Ikemoto, Takeshi Asano, Akemi Shodai, Takuji Fujita, Satoshi Fukui, Hiroyuki Morino, Satoshi Nakano, Hirofumi Kusaka, Hirofumi Yamashita, Masafumi Ihara, Riki Matsumoto, Jun Kawamata, Makoto Urushitani, Hideshi Kawakami, Ryosuke Takahashi
Acta Neuropathologica Communications   2    Jan 2014
© 2014 Ayaki et al.; licensee BioMed Central. Background: Mutations in the valosin-containing protein (VCP) gene were first found to cause inclusion- body myopathy with early-onset Paget disease and frontotemporal dementia (IBMPFD). Mutations in t...
Shigetoshi Takaya, Akio Ikeda, Takahiro Mitsueda-Ono, Riki Matsumoto, Morito Inouchi, Chihiro Namiki, Naoya Oishi, Nobuhiro Mikuni, Koichi Ishizu, Ryosuke Takahashi, Hidenao Fukuyama
Journal of Neuroimaging   24 54-62   Jan 2014
BACKGROUND AND PURPOSE: Temporal lobe epilepsy (TLE) with nontumoral amygdala enlargement (AE) has been reported to be a possible subtype of TLE without hippocampal sclerosis (HS). The purpose of this study was to clarify morphologic and functiona...
Yasuhide Takeuchi, Yoshiki Arakawa, Yoshiki Mikami, Riki Matsumoto, Susumu Miyamoto
Brain Tumor Pathology   31 144-148   Jan 2014
Dysembryoplastic neuroepithelial tumor (DNT) rarely has aggressive behavior with recurrence. The authors describe a case of DNT with rapid re-growth and features of pilocytic astrocytoma. A 19-year-old girl presented with a 3-year history of compl...
Naoto Jingami, Riki Matsumoto, Hirotaka Ito, Atsushi Ishii, Yukiko Ihara, Shinichi Hirose, Akio Ikeda, Ryosuke Takahashi
Epileptic Disorders   16 227-231   Jan 2014
Generalised (genetic) epilepsy with febrile seizures plus (GEFS+) is a familial epilepsy syndrome with various phenotypes. The majority of individuals with GEFS+ have generalised seizure types, in addition to febrile seizures (FS) or febrile seizu...
Yukihiro Yamao, Riki Matsumoto, Takeharu Kunieda, Yoshiki Arakawa, Katsuya Kobayashi, Kiyohide Usami, Sumiya Shibata, Takayuki Kikuchi, Nobukatsu Sawamoto, Nobuhiro Mikuni, Akio Ikeda, Hidenao Fukuyama, Susumu Miyamoto
Human Brain Mapping   35 4345-4361   Jan 2014
The preservation of language function during brain surgery still poses a challenge. No intraoperative methods have been established to monitor the language network reliably. We aimed to establish intraoperative language network monitoring by means...
Maya Tojima, Takefumi Hitomi, Naoto Jingami, Kosuke Tanioka, Hodaka Yamakado, Riki Matsumoto, Yukitoshi Takahashi, Akio Ikeda, Ryosuke Takahashi
Clinical Neurology   54 543-549   Jan 2014
Patient 1 was a 40-year-old man, who suffered from right leg myoclonus 1 week after an episode of fever and headache. Myoclonus disappeared 4 months after administration of clonazepam. Patient 2 was a 42-year-old man, who suffered from right leg m...
Takeshi Inoue, Riki Matsumoto, Akio Ikeda
Nihon rinsho. Japanese journal of clinical medicine   72 853-858   Jan 2014
For treatment of epilepsy in patients of adolescence and adulthood, we always take into account all the 3 aspects of 1) diagnosis of seizure type and epilepsy syndrome, 2) existence of comorbidity and 3) interaction between concomitant drugs, and ...
Kyoko Kanazawa, Riki Matsumoto, Akihiro Shimotake, Masako Kinoshita, Akiko Otsuka, Osamu Watanabe, Keiko Tanaka, Ryosuke Takahashi, Akio Ikeda
Epileptic Disorders   16 312-317   Jan 2014
Conclusions: EEG seizure patternsmay persist years after clinical seizure remissionin "smoldering" limbic encephalitis and lead to memory impairment.Results: The two patients were positive for anti-voltage-gated potassium channel complex antibody ...
Katsuya Kobayashi, Takefumi Hitomi, Riki Matsumoto, Takayuki Kondo, Jun Kawamata, Masao Matsuhashi, Shuji Hashimoto, Hitoshi Ikeda, Yasumichi Koide, Yushi Inoue, Ryosuke Takahashi, Akio Ikeda
Seizure   23 746-750   Jan 2014
© 2014 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved. Purpose To delineate chronological changes of cortical hyperexcitability by long-term follow-up of the amplitudes of somatosensory evoked potentials (SEPs) in pat...
Emiko Morimoto, Tomohisa Okada, Mitsunori Kanagaki, Akira Yamamoto, Yasutaka Fushimi, Riki Matsumoto, Shigetoshi Takaya, Akio Ikeda, Takeharu Kunieda, Takayuki Kikuchi, Dominik Paul, Susumu Miyamoto, Ryosuke Takahashi, Kaori Togashi
Epilepsia   54 2174-2183   Dec 2013
Purpose To quantitatively compare the diagnostic capability of double inversion-recovery (DIR) with F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) for detection of seizure focus laterality in temporal lobe epilepsy (TLE). Methods T...
Takefumi Hitomi, Katsuya Kobayashi, Naoto Jingami, Tomokazu Nakagawa, Hisaji Imamura, Riki Matsumoto, Takayuki Kondo, Kazuo Chin, Ryosuke Takahashi, Akio Ikeda
Epileptic Disorders   15 428-432   Dec 2013
We recently reported clinical anticipation in Japanese families with benign adult familial myoclonus epilepsy (BAFME). However, it remains unknown whether clinical anticipation is predominantly associated with paternal or maternal transmission. We...
Takeharu Kunieda, Nobuhiro Mikuni, Sumiya Shibata, Rika Inano, Yukihiro Yamao, Takayuki Kikuchi, Riki Matsumoto, Jun Takahashi, Akio Ikeda, Hidenao Fukuyama, Susumu Miyamoto
Neurologia Medico-Chirurgica   53 805-813   Nov 2013
Surgical intervention is expected to improve the quality of life in patients with intractable epilepsy by providing adequate seizure control. Although many previous studies showed various rates of seizure freedom, definite conclusions have not yet...
Morito Inouchi, Riki Matsumoto, Junya Taki, Takayuki Kikuchi, Takahiro Mitsueda-Ono, Nobuhiro Mikuni, Lewis Wheaton, Mark Hallett, Hidenao Fukuyama, Hiroshi Shibasaki, Ryosuke Takahashi, Akio Ikeda
Clinical Neurophysiology   124 2230-2241   Nov 2013
Objective: To clarify the spatio-temporal profile of cortical activity related to reaching movement in the posterior parietal cortex (PPC) in humans. Methods: Four patients with intractable partial epilepsy who underwent subdural electrode implant...
Rei Enatsu, Riki Matsumoto, Zhe Piao, Timothy O'Connor, Karl Horning, Richard C. Burgess, Juan Bulacio, William Bingaman, Dileep R. Nair
Cortex   49 2080-2096   Sep 2013
The purpose of this study was to investigate the connectivity from the negative motor area and to elucidate the mechanism of negative motor phenomena. We report the results of cortico-cortical evoked potentials (CCEPs) by electrical stimulation of...
Yuriko Nakaoku, Takakuni Maki, Kyoko Kanazawa, Riki Matsumoto, Hidenao Fukuyama, Ryosuke Takahashi, Akio Ikeda
Clinical Neurology   53 706-711   Sep 2013
We report a 59-year-old right-handed woman with smoldering leucine-rich glioma-inactivated 1 (LGI1) antibody-associated limbic encephalitis (LE) following faciobrachial dystonic seizures. During 8 months before her admission, she developed partial...
Tomoyuki Fumuro, Masao Matsuhashi, Takahiro Mitsueda, Morito Inouchi, Takefumi Hitomi, Tomokazu Nakagawa, Riki Matsumoto, Jun Kawamata, Haruhisa Inoue, Tatsuya Mima, Ryosuke Takahashi, Akio Ikeda
Clinical Neurophysiology   124 1398-1405   Jul 2013
Objective: Decreased early Bereitschaftspotential (BP) is one of the electrophysiological characteristics in patients with Parkinson's disease (PD). We examined whether PD patients could increase BP amplitude by means of neuro-feedback (NFB) train...
Yukihiro Yamao, Takeharu Kunieda, Takayuki Kikuchi, Masao Matsuhashi, Nobukatsu Sawamoto, Riki Matsumoto, Tomohisa Okada, Susumu Miyamoto, Akio Ikeda
Brain and Nerve   65 573-581   May 2013
It is now recommended that magnetic resonance imaging (MRI) or computed tomography (CT) be carried out in all patients with at least partial- and hopefully also generalized epilepsy to help identify intracranial lesions, such as hippocampal sclero...
Takahiro Mitsueda-Ono, Akio Ikeda, Nobukatsu Sawamoto, Toshihiko Aso, Takashi Hanakawa, Masako Kinoshita, Riki Matsumoto, Nobuhiro Mikuni, Shigeru Amano, Hidenao Fukuyama, Ryosuke Takahashi
Internal Medicine   52 877-885   Apr 2013
Objective Hippocampal sclerosis (HS) is observed in many intractable, mesial temporal lobe epilepsy (MTLE) patients. We aimed to delineate the internal structural changes (ISC) shown as loss of internal architecture in the hippocampus on 3-Tesla m...
Kiyohide Usami, Riki Matsumoto, Takeharu Kunieda, Akihiro Shimotake, Masao Matsuhashi, Susumu Miyamoto, Hidenao Fukuyama, Ryosuke Takahashi, Akio Ikeda
Neuropsychologia   51 1011-1017   Apr 2013
Previous non-invasive studies have proposed that the deeply seated region of the medial frontal cortex engages in conflict processing in humans, but its core region has remained to be elucidated. By means of direct cortical stimulation, which exce...
Emiko Morimoto, Mitsunori Kanagaki, Tomohisa Okada, Akira Yamamoto, Nobuyuki Mori, Riki Matsumoto, Akio Ikeda, Nobuhiro Mikuni, Takeharu Kunieda, Dominik Paul, Susumu Miyamoto, Ryosuke Takahashi, Kaori Togashi
European Radiology   23 3-11   Jan 2013
Objectives: To investigate the diagnostic capability of anterior temporal lobe white matter abnormal signal (ATLAS) for determining seizure focus laterality in temporal lobe epilepsy (TLE) by comparing different MR sequences. Methods: This prospec...
Yasukiyo Araki, Eiko Nakano Minakawa, Miki Ono, Riki Matsumoto, Masako Kinoshita
Epilepsy and Seizure   6 10-18   Jan 2013
Purpose: To evaluate the efficacy and tolerability of topiramate (TPM) as add-on therapy in Japanese adult patients with refractory epilepsy. Methods: We performed a retrospective open-label study on 39 Japanese adult patients with refractory seiz...
Riki Matsumoto, Dileep R. Nair, Akio Ikeda, Tomoyuki Fumuro, Eric Lapresto, Nobuhiro Mikuni, William Bingaman, Susumu Miyamoto, Hidenao Fukuyama, Ryosuke Takahashi, Imad Najm, Hiroshi Shibasaki, Hans O. Lüders
Human Brain Mapping   33 2856-2872   Dec 2012
Parieto-frontal network is essential for sensorimotor integration in various complex behaviors, and its disruption is associated with pathophysiology of apraxia and visuo-spatial disorders. Despite advances in knowledge regarding specialized corti...
Riki Matsumoto, Takeharu Kunieda, Ryosuke Takahashi, Akio Ikeda
Clinical Neurology   52 1084-1087   Dec 2012
It is the cortices and the cortico-cortical connections that are involved in manifestation of normal cortical functions as well as production of seizure symptoms. In this sense, presurgical evaluation of patients with intractable partial epilepsy ...
Masao Matsuhashi, Tatsuya Mima, Hidenao Fukuyama, Riki Matsumoto, Katsuya Kobayashi, Akio Ikeda, Yukihiro Yamao, Sumiya Shibata, Yohei Yokoyama, Takeharu Kunieda, Nobuhiro Mikuni
2012 ICME International Conference on Complex Medical Engineering, CME 2012 Proceedings   221-224   Oct 2012
In order to improve epileptic focus localization performance of non-invasive recording, we propose a new method to estimates and visualize the spatio-temporal spread pattern of the epileptic spike activities especially at the onset of spikes when ...
Yoichiro Okada, Takashi Ayaki, Riki Matsumoto, Hidefumi Ito, Ryosuke Takahashi, Satoshi Nakano
Clinical Neurology   52 774-777   Oct 2012
A 53-year-old man presented mild, but gradually worsening, distal-dominant upper bilateral limbs weakness and muscle cramp in both legs from the age of 30. He had no obvious muscle atrophy during the course of the disease. Muscle biopsy of the rig...
Riki Matsumoto, Takeharu Kunieda, Akio Ikeda
Brain and Nerve   64 979-991   Sep 2012
A better understanding of seizure networks and the mechanisms underlying human higher cortical functions requires a detailed knowledge of neuronal connectivity. As it relates to higher cortical functions, such as language, in humans, studies perfo...
Masanori Azuma, Isao Ito, Riki Matsumoto, Toyohiro Hirai, Michiaki Mishima
Heart and Lung: Journal of Acute and Critical Care   41 290-293   May 2012
We report a 35-year-old man who presented with pulmonary hemorrhage induced by an epileptic seizure. He had experienced recurrent episodes of massive hemoptysis after epileptic seizures since the age of 28 years. He was admitted to Kyoto Universit...
Takayuki Kikuchi, Riki Matsumoto, Nobuhiro Mikuni, Yohei Yokoyama, Atsuhito Matsumoto, Akio Ikeda, Hidenao Fukuyama, Susumu Miyamoto, Nobuo Hashimoto
Clinical Neurophysiology   123 324-334   Feb 2012
Objective: This study aimed to clarify the function of human supplementary motor area proper (SMA) by the single-pulse electric stimulation method and its clinical usefulness for SMA mapping. Methods: We studied five patients with epilepsy or brai...
Takefumi Hitomi, Takayuki Kondo, Katsuya Kobayashi, Riki Matsumoto, Ryosuke Takahashi, Akio Ikeda
Epilepsia   53    Feb 2012
The clinical anticipation in Japanese benign adult familial myoclonus epilepsy (BAFME), defined as earlier onset age of either cortical tremor or generalized seizures or new appearance of those symptoms in the next generation, remains unknown. The...
Kosuke Tanioka, Miki Nagao, Masaki Yamamoto, Yasufumi Matsumura, Hayato Tabu, Aki Matsushima, Kengo Uemura, Riki Matsumoto, Yutaka Ito, Shunji Takakura, Ryosuke Takahashi, Satoshi Ichiyama
Journal of Infection and Chemotherapy   18 390-394   Jan 2012
Nocardiosis is increasingly being diagnosed because of a growing population of immunocompromised hosts and improvements in the detection of Nocardia species in clinical laboratories. Historically, sulphonamides have been the first-line therapy for...
Takefumi Hitomi, Akio Ikeda, Morito Inouchi, Hisaji Imamura, Tomokazu Nakagawa, Tomoyuki Fumuro, Riki Matsumoto, Ryosuke Takahashi
Internal Medicine   50 2303-2309   Oct 2011
Objective: To clarify the clinical features and mechanism of the transience of myoclonus in patients with a transient myoclonic state with asterixis (TMA). Methods: We investigated the clinical and eletrophysiological profiles of 6 patients with T...
Joanne M. Wrench, Riki Matsumoto, Yushi Inoue, Sarah J. Wilson
Epilepsy and Behavior   22 23-31   Sep 2011
The accurate prediction of individual outcomes after epilepsy surgery represents a key challenge facing clinicians. It requires a precise understanding of surgical candidacy and the optimal timing of surgery to maximize a range of outcomes, includ...
Hisaji Imamura, Riki Matsumoto, Morito Inouchi, Masao Matsuhashi, Nobuhiro Mikuni, Ryosuke Takahashi, Akio Ikeda
Clinical Neurophysiology   122 1500-1504   Aug 2011
Objective: With advanced electroencephalography (EEG) technology, 'wideband EEG' ranging from slow shift to high frequency oscillation (HFO) is clinically available to study human epileptogenesis.The purpose of our study is to clarify the relation...
Katsuya Kobayashi, Riki Matsumoto, Takayuki Kondo, Jun Kawamata, Takefumi Hitomi, Morito Inouchi, Masao Matsuhashi, Ryosuke Takahashi, Akio Ikeda
Clinical Neurophysiology   122 1617-1621   Aug 2011
Objective: To delineate long-term change of cortical excitability by measuring somatosensory evoked potentials (SEPs) in patients with Unverricht-Lundborg disease (ULD). Methods: SEPs to median nerve stimulation were repeatedly examined in two gen...
Takefumi Hitomi, Akio Ikeda, Takayuki Kondo, Hisaji Imamura, Morito Inouchi, Riki Matsumoto, Kiyohito Terada, Masutaro Kanda, Masao Matsuhashi, Takashi Nagamine, Hiroshi Shibasaki, Ryosuke Takahashi
Movement Disorders   26 1509-1514   Jul 2011
The clinical implications of enlarged early cortical components of somatosensory evoked potentials in benign adult familial myoclonus epilepsy remain unknown. Somatosensory evoked potentials following electrical stimulation of the median nerve at ...
Takahiro Mitsueda-Ono, Akio Ikeda, Morito Inouchi, Shigetoshi Takaya, Riki Matsumoto, Takashi Hanakawa, Nobukatsu Sawamoto, Nobuhiro Mikuni, Hidenao Fukuyama, Ryosuke Takahashi
Journal of Neurology, Neurosurgery and Psychiatry   82 652-657   Jun 2011
Objective: The purpose of the study was to clarify the significance of amygdalar enlargement (AE) in patients with temporal lobe epilepsy (TLE) detected by MRI. Methods: 11 TLE patients (eight men, mean age 45.3 (SD 18.2) years) with AE treated at...
Eiichi Naito, Riki Matsumoto, Nobuhiro Hagura, Yutaka Oouchida, Hidekazu Tomimoto, Takashi Hanakawa
Neurocase   17 133-147   Apr 2011
Prompted by our neuroimaging findings in 60 normal people, we examined whether focal damage to the hand section of precentral motor regions impairs hand kinesthesia in a patient, and investigated brain regions related to recovery of kinesthetic fu...
Takakuni Maki, Riki Matsumoto, Nobuo Kohara, Takayuki Kondo, Insuk Sun, Takahiro Mezaki, Ichizo Nishino, Akio Ikeda, Ryosuke Takahashi
Muscle and Nerve   43 601-605   Apr 2011
Rippling muscle disease (RMD) is a myopathy with hyperirritability, the pathophysiology for which is uncertain. We report electromyographic findings in a 30-year-old man with RMD. Clinical features included muscle rippling and percussion-induced r...
Riki Matsumoto, Hisaji Imamura, Morito Inouchi, Tomokazu Nakagawa, Yohei Yokoyama, Masao Matsuhashi, Nobuhiro Mikuni, Susumu Miyamoto, Hidenao Fukuyama, Ryosuke Takahashi, Akio Ikeda
Neuropsychologia   49 1350-1354   Apr 2011
Recent neuroimaging studies proposed the importance of the anterior auditory pathway for speech comprehension. Its clinical significance is implicated by semantic dementia or pure word deafness. Neurodegenerative or cerebrovascular nature, however...
Kyoko Kanazawa, Riki Matsumoto, Masako Kinoshita, Akio Ikeda
Brain and Nerve   63 355-364   Apr 2011
Seizure onset zone (SOZ) is currently defined by ictal epileptiform discharges, which are most commonly recorded as regional low-voltage fast waves or repetitive spikes. Interictal epileptiform discharges, on the other hand, are not specific enoug...
Masaki Iwasaki, Rei Enatsu, Riki Matsumoto, Eric Novak, Baburaj Thankappen, Zhe Piao, Tim O'Connor R, Karl Horning, William Bingaman, Dileep Nair
Epileptic Disorders   12 292-302   Dec 2010
Objective. To determine whether patients with neocortical epilepsy show evidence for increased excitability measured by cortico-cortical evoked potentials (CCEPs) in ictal-onset regions. Methods. In patients undergoing intracranial recordings with...
Takashi Hanakawa, Tatsuya Mima, Riki Matsumoto, Mitsunari Abe, Morito Inouchi, Shin Ichi Urayama, Kimitaka Anami, Manabu Honda, Hidenao Fukuyama
Cerebral Cortex   19 2605-2615   Nov 2009
We examined the stimulus-response profile during single-pulse transcranial magnetic stimulation (TMS) by measuring motor-evoked potentials (MEPs) with electromyographic monitoring and hemodynamic responses with functional magnetic resonance imagin...
Keiko Usui, Akio Ikeda, Takashi Nagamine, Jun Matsubayashi, Riki Matsumoto, Harukazu Hiraumi, Jun Kawamata, Masao Matsuhashi, Ryosuke Takahashi, Hidenao Fukuyama
Clinical Neurophysiology   120 1923-1926   Nov 2009
Objective: Lateralization of functionally abnormal cortical area in autosomal dominant lateral temporal lobe epilepsy (ADLTE). Methods: A sound pulse of pure tone was delivered monaurally to the ears alternately. Auditory evoked magnetic fields (A...

Research Grants & Projects

 
Neural Basis for Semantic Network: A Combinded Electrocorticographic Decoding, Stimulation and Lesion Study
JSPS: Grant-in-Aid for Scientific Research (B)
Project Year: Apr 2018 - Mar 2022    Investigator(s): Riki Matsumoto
Development of Non-Invasive Language Mapping: Paradigm Shift From Direct Electrical Stimulation to Electrocorticographic Neural Decoding
JSPS: Grant-in-Aid for Challenging Exploratory Research
Project Year: Jun 2018 - Mar 2021    Investigator(s): Riki Matsumoto
Human Fronto-Parietal Network for Embodied-Brain System: A Combined Electrocorticographic Decoding, Stimulation and Lesion Study
JSPS: Grant-in-Aid for Scientific Research on Innovative Areas: Embodied-Brain
Project Year: Apr 2017 - Mar 2017    Investigator(s): Riki Matsumoto
Neural basis of human body representation: a direct electrocorticographic recording and stimulation study
JSPS: Grant-in-Aid for Scientific Research on Innovative Areas: Embodied-Brain
Project Year: Jun 2015 - Mar 2017    Investigator(s): Riki Matsumoto
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2008 - 2010    Investigator(s): Nobuhiro MIKUNI
We have studied the mechanisms underlying epileptogenesis in cortical dysplasia by using a rat model and a human specimen. The results have shown that excitatory postsynaptic NMDA receptors played a critical role of epilepsy associated with cortic...