長原恵 (Megumi Nagahara) - マイポータル

基本情報

所属: 徳島大学バイオイノベーション研究所特任准教授

学位: 農学士(2002年3月東京農業大学)
獣医学士(2016年3月山口大学)
工学博士(2022年11月徳島大学)

研究者番号: 00981284
J-GLOBAL ID: 202301001623400586
researchmap会員ID: R000050473

研究キーワード

研究分野

経歴

2023年4月 - 現在

徳島大学, バイオイノベーション研究所, 特任准教授
2023年4月 - 2025年3月

徳島大学, 大学院社会産業理工学研究部, 助教

学歴

2011年4月 - 2016年3月

山口大学, 農学部, 獣医学科
1998年4月 - 2002年3月

東京農業大学, 農学部, 畜産学科

論文

Selection of two pronuclei zygotes before electroporation does not improve gene editing efficiency or reduce mosaicism in porcine embryos despite optimized timing and Hoechst staining

Koki Takebayashi, Takeshige Otoi, Manita Wittayarat, Oky Setyo Widodo, Theerawat Tharasanit, Kaywalee Chatdarong, Yuichiro Nakayama, Zhao Namula, Megumi Nagahara, Maki Hirata …

Veterinary World 2026年6月30日
Double Electroporation Combined with Zona Pellucida Removal Improves Biallelic Genome Editing Efficiency in Porcine Embryos

Nanaka Torigoe, Takeshige Otoi, Manita Wittayarat, Oky Setyo Widodo, Theerawat Tharasanit, Kaywalee Chatdarong, Megumi Nagahara, Maki Hirata, Fuminori Tanihara, Zhao Namula

Animals 2026年6月20日
Development of a Portable Device–Based Method for Predicting Follicle Number Using Vulvar Blood Flow Volume Measurement in Cows

Megumi Nagahara, Takeshige Otoi, Momo Nakagawa, Kazuki Yoshida, Shigeki Morikawa, Kohei Torii, Oky Setyo Widodo, Mao Matsushita, Yuichiro Nakayama, Fuminori Tanihara

Animal Science Journal 2026年1月
Synergistic enhancement of clustered regularly interspaced short palindromic repeats (CRISPR) / CRISPR-associated protein 9 -mediated gene editing in porcine zygotes through combined lipofection and electroporation of cationic lipid-packaged ribonucleoproteins

Qingyi Lin, Takeshige Otoi, Oky Setyo Widodo, Theerawat Tharasanit, Kaywalee Chatdarong, Zhao Namula, Maki Hirata, Aya Nakai, Yuichiro Nakayama, Megumi Nagahara …

Veterinary World 2025年12月31日
IL2RG deficient X-SCID pigs generated via electroporation-mediated gene editing using CRISPR/Cas9.

Maki Hirata, Zhao Namula, Qingyi Lin, Megumi Nagahara, Shangquan Gan, Xianghong Ju, Koki Takebayashi, Aya Nakai, Manita Wittayarat, Takeshige Otoi …

Journal of animal science 2025年11月18日
Establishment of a Single-Oocyte Culture System for Pigs and Its Validation Using Curcumin as a Model Antioxidant for Oocyte Maturation

Zhao Namula, Takeshige Otoi, Theerawat Tharasanit, Kaywalee Chatdarong, Megumi Nagahara, Oky Setyo Widodo, Aya Nakai, Suong Thi Nguyen, Yuichiro Nakayama, Maki Hirata …

Animals 2025年11月14日
Indole-3-propionic acid supplementation during in vitro maturation improves in vitro production of porcine embryos.

Yuichiro Nakayama, Takeshige Otoi, Namula Zhao, Suong Thi Nguyen, Nanaka Torigoe, Qyingi Lin, Liu Bin, Oky Setyo Widodo, Theerawat Tharasanit, Kaywalee Chatdarong …

BMC veterinary research 21(1) 642-642 2025年11月3日
Mitochondrial-Targeted Protective Potential of Elamipretide for the In Vitro Production of Porcine Embryos

Suong T. Nguyen, Takeshige Otoi, Zhao Namula, Oky Setyo Widodo, Theerawat Tharasanit, Kaywalee Chatdarong, Yuichiro Nakayama, Megumi Nagahara, Aya Nakai, Maki Hirata …

Animals 2025年8月25日
Oxidative stress index of porcine follicular fluid influences meiotic maturation and embryo development during in vitro culture

Bin Liu, Takeshige Otoi, Zhao Namula, Oky Setyo Widodo, Maki Hirata, Aya Nakai, Qingyi Lin, Yuichiro Nakayama, Megumi Nagahara, Fuminori Tanihara

Veterinary World 2025年7月
Aberrant Expression Levels of Androgen Receptor and SRD5A2 in Epididymal Epithelial Cells of Crossbred Infertile Cattle–Yak

Manita Wittayarat, Kimika Kawanishi, Haruka Ohata, Megumi Nagahara, Rentsenkhand Sambuu, Otgonjargal Sambuu, Maki Hirata, Fuminori Tanihara, Masayasu Taniguchi, Takeshige Otoi …

Animals 2025年2月24日
Analysis of myofiber composition in myostatin monoallelic mutant pigs

M. Nagahara, M. Hirata, Q. Lin, K. Takebayashi, A. Nakai, T. Otoi, F. Tanihara

Journal of Livestock Science 16(2) 168-172 2025年2月12日
Effects of Electroporation Timing and Cumulus Cell Attachment on In Vitro Development and Genome Editing of Porcine Embryos.

Nanaka Torigoe, Qingyi Lin, Bin Liu, Yuichiro Nakayama, Aya Nakai, Megumi Nagahara, Fuminori Tanihara, Maki Hirata, Takeshige Otoi

Reproduction in domestic animals = Zuchthygiene 60(2) e70011 2025年2月
Zinc Chloride Supplementation During In Vitro Fertilization Reduces Polyspermic Fertilization of Porcine Oocytes

Supitcha Kaewma, Takeshige Otoi, Oky Setyo Widodo, Megumi Nagahara, Aya Nakai, Suong T. Nguyen, Yuichiro Nakayama, Theerawat Tharasanit, Maki Hirata, Fuminori Tanihara

Animal Science Journal 2025年1月
Genome editing of porcine zygotes via lipofection of two guide RNAs using a CRISPR/Cas9 system.

Qingyi Lin, Koki Takebayashi, Nanaka Torigoe, Bin Liu, Zhao Namula, Maki Hirata, Fuminori Tanihara, Megumi Nagahara, Takeshige Otoi

The Journal of reproduction and development 70(6) 356-361 2024年12月13日
Efficient gene editing of pig embryos by combining electroporation and lipofection

Qingyi Lin, Nanaka Torigoe, Bin Liu, Yuichiro Nakayama, Aya Nakai, Zhao Namula, Megumi Nagahara, Fuminori Tanihara, Maki Hirata, Takeshige Otoi

Veterinary World 2024年11月
Optimization of embryonic stage for aggregation to generate chimeric pigs using gene-edited blastomeres.

Koki Takebayashi, Manita Wittayarat, Maki Hirata, Qingyi Lin, Zhao Namula, Nanaka Torigoe, Bin Liu, Megumi Nagahara, Aya Nakai, Takeshige Otoi …

In vitro cellular & developmental biology. Animal 2024年10月24日
Generation of allogenic chimera carrying mutations in PDX1 and TP53 genes via phytohemagglutinin-mediated blastomere aggregation in pigs.

Thanh-Van Nguyen, Koki Takebayashi, Lanh Thi Kim Do, Zhao Namula, Manita Wittayarat, Megumi Nagahara, Maki Hirata, Takeshige Otoi, Fuminori Tanihara

In vitro cellular & developmental biology. Animal 60(7) 708-715 2024年8月
Programmed cell death-1-modified pig developed using electroporation-mediated gene editing for in vitro fertilized zygotes.

Thanh-Van Nguyen, Lanh Thi Kim Do, Qingyi Lin, Megumi Nagahara, Zhao Namula, Manita Wittayarat, Maki Hirata, Takeshige Otoi, Fuminori Tanihara

In vitro cellular & developmental biology. Animal 60(7) 716-724 2024年8月
Evaluation of culture methods and chemical reagent combinations on CRISPR/Cas9 gene editing systems by lipofection in pig zygotes.

Qingyi Lin, Koki Takebayashi, Nanaka Torigoe, Bin Liu, Zhao Namula, Maki Hirata, Megumi Nagahara, Fuminori Tanihara, Takeshige Otoi

In vitro cellular & developmental biology. Animal 60(7) 725-731 2024年8月
Effects of centrifugation treatment before electroporation on gene editing in pig embryos.

Bin Liu, Manita Wittayarat, Koki Takebayashi, Qingyi Lin, Nanaka Torigoe, Zhao Namula, Maki Hirata, Megumi Nagahara, Fuminori Tanihara, Takeshige Otoi

In vitro cellular & developmental biology. Animal 60(7) 732-739 2024年8月

もっとみる

MISC

ヤクー牛雑種の雄性不稔に関わる精巣上体細胞サイズの検討

佐藤陽子, 長原恵, 小笠原亮太, 大畠有貴, 川西君佳, 大畑遥, 柴田康暉, 杵淵茜, 東原由佳, 菅谷紀秀 …

日本分子生物学会年会プログラム・要旨集(Web) 46th 2023年

共同研究・競争的資金等の研究課題

UV-C技術を用いた医用ドナーブタの高度衛生管理方法の確立

日本学術振興会科学研究費助成事業基盤研究(C) 2025年4月 - 2028年3月

長原恵, 平田真樹, 粟飯原睦美, 谷原史倫

長原恵

基本情報

研究キーワード

研究分野

経歴

学歴

論文

MISC

共同研究・競争的資金等の研究課題

メニュー

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