Masahiro Enomoto - My portal

Profile Information

J-GLOBAL ID: 201301010635383930
researchmap Member ID: B000233280

External link: http://kaken.nii.ac.jp/d/r/50435632.ja.html

Research Interests

Research Areas

Research History

Apr, 2011 - Present

Postdoctoral fellow, Mitsu Ikura Lab, Ontario Cancer Institute
Apr, 2006 - Mar, 2011

Researcher, Brain Science Institute, RIKEN
Apr, 2007 - Mar, 2010

Special postdoctoral researcher, RIKEN
Apr, 2003 - Mar, 2006

Research Fellow of the Japan Society for the Promotion, The Japan Society for the Promotion

Education

Apr, 2001 - Mar, 2006

Department of Biological Sciences, School of Science, The University of Tokyo

Awards

Jul, 2011

Best presentation award, Blockage of spontaneous Ca2+ oscillation causes cell death in intraerythrocitic Plasmodium falciparum., The 80th Annual meeting of the Japanese Society of Parasitology

Masahiro Enomoto

Papers

Simultaneous Administration of 2-Aminoethyl Diphenylborinate and Chloroquine Reverses Chloroquine Resistance in Malaria Parasites

Ehab Mossaad, Wakako Furuyama, Masahiro Enomoto, Satoru Kawai, Katsuhiko Mikoshiba, Shin-ichiro Kawazu

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 59(5) 2890-2892, May, 2015 Peer-reviewed
Structural insights into endoplasmic reticulum stored calcium regulation by inositol 1,4,5-trisphosphate and ryanodine receptors.

Seo MD, Enomoto M, Ishiyama N, Stathopulos PB, Ikura M

Biochimica et biophysica acta, Nov, 2014 Peer-reviewed
Intracellular calcium channels: Inositol-1,4,5-trisphosphate receptors

Olena A. Fedorenko, Elena Popugaeva, Masahiro Enomoto, Peter B. Stathopulos, Mitsuhiko Ikura, Ilya Bezprozvanny

EUROPEAN JOURNAL OF PHARMACOLOGY, 739 39-48, Sep, 2014 Peer-reviewed
An interplay between 2 signaling pathways: Melatonin-cAMP and IP3-Ca2+ signaling pathways control intraerythrocytic development, of the malaria parasite Plasmodium falciparum

Wakako Furuyama, Masahiro Enomoto, Ehab Mossaad, Satoru Kawai, Katsuhiko Mikoshiba, Shin-ichiro Kawazu

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 446(1) 125-131, Mar, 2014 Peer-reviewed
Antisense Oligonucleotides Targeting Parasite Inositol 1,4,5-Trisphosphate Receptor Inhibits Mammalian Host Cell Invasion by Trypanosoma cruzi

Muneaki Hashimoto, Takeshi Nara, Hiroko Hirawake, Jorge Morales, Masahiro Enomoto, Katsuhiko Mikoshiba

SCIENTIFIC REPORTS, 4 4231, Feb, 2014 Peer-reviewed
CaBP1, a neuronal Ca2+ sensor protein, inhibits inositol trisphosphate receptors by clamping intersubunit interactions.

Li C, Enomoto M, Rossi AM, Seo MD, Rahman T, Stathopulos PB, Taylor CW, Ikura M, Ames JB

Proceedings of the National Academy of Sciences of the United States of America, 110 8507-8512, May, 2013 Peer-reviewed
Inositol 1,4,5-trisphosphate receptor regulates replication, differentiation, infectivity and virulence of the parasitic protist Trypanosoma cruzi

Muneaki Hashimoto, Masahiro Enomoto, Jorge Morales, Nagomi Kurebayashi, Takashi Sakurai, Tetsuo Hashimoto, Takeshi Nara, Katsuhiko Mikoshiba

MOLECULAR MICROBIOLOGY, 87(6) 1133-1150, Mar, 2013 Peer-reviewed
Ryanodine receptor calcium release channels: lessons from structure-function studies.

Amador FJ, Stathopulos PB, Enomoto M, Ikura M

The FEBS journal, Feb, 2013 Peer-reviewed
Regulation of the cell proliferation and migration as extra-pituitary functions of GnRH

Min Kyun Park, Yoh-Ichiro Kanaho, Masahiro Enomoto

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 181 259-264, Jan, 2013 Peer-reviewed
Themes and Variations in ER/SR Calcium Release Channels: Structure and Function

Peter B. Stathopulos, Min-duk Seo, Masahiro Enomoto, Fernando J. Amador, Noboru Ishiyama, Mitsuhiko Ikura

PHYSIOLOGY, 27(6) 331-342, Dec, 2012 Peer-reviewed
Blockage of Spontaneous Ca2+ Oscillation Causes Cell Death in Intraerythrocitic Plasmodium falciparum

Masahiro Enomoto, Shin-ichiro Kawazu, Satoru Kawai, Wakako Furuyama, Tohru Ikegami, Jun-ichi Watanabe, Katsuhiko Mikoshiba

PLOS ONE, 7(7) e39499, Jul, 2012 Peer-reviewed
Receptor-Selective Diffusion Barrier Enhances Sensitivity of Astrocytic Processes to Metabotropic Glutamate Receptor Stimulation

Misa Arizono, Hiroko Bannai, Kyoko Nakamura, Fumihiro Niwa, Masahiro Enomoto, Toru Matsu-ura, Akitoshi Miyamoto, Mark W. Sherwood, Takeshi Nakamura, Katsuhiko Mikoshiba

SCIENCE SIGNALING, 5(218) ra27, Apr, 2012 Peer-reviewed
Mechanistic basis of bell-shaped dependence of inositol 1,4,5-trisphosphate receptor gating on cytosolic calcium

Tadashi Shinohara, Takayuki Michikawa, Masahiro Enomoto, Jun-Ichi Goto, Miwako Iwai, Toru Matsu-ura, Haruka Yamazaki, Akitoshi Miyamoto, Akio Suzuki, Katsuhiko Mikoshiba

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108(37) 15486-15491, Sep, 2011 Peer-reviewed
Highly Cooperative Dependence of Sarco/Endoplasmic Reticulum Calcium ATPase (SERCA) 2a Pump Activity on Cytosolic Calcium in Living Cells

Kanayo Satoh, Toru Matsu-ura, Masahiro Enomoto, Hideki Nakamura, Takayuki Michikawa, Katsuhiko Mikoshiba

JOURNAL OF BIOLOGICAL CHEMISTRY, 286(23) 20591-20599, Jun, 2011 Peer-reviewed
Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B

Sayaka Tanaka, Hiroyuki Kabayama, Masahiro Enomoto, Nobuhito Saito, Katsuhiko Mikoshiba

JOURNAL OF PHYSIOLOGICAL SCIENCES, 61(3) 221-229, May, 2011 Peer-reviewed
Neurotrophic Effect of Gonadotropin-Releasing Hormone on Neurite Extension and Neuronal Migration of Embryonic Gonadotropin-Releasing Hormone Neurons in Chick Olfactory Nerve Bundle Culture

Yoh-Ichiro Kanaho, Masahiro Enomoto, Daisuke Endo, Sayaka Maehiro, Min Kyun Park, Shizuko Murakami

JOURNAL OF NEUROSCIENCE RESEARCH, 87(10) 2237-2244, Aug, 2009 Peer-reviewed
Gonadotropin-releasing hormone induces actin cytoskeleton remodeling and affects cell migration in a cell-type-specific manner in TSU-Pr1 and DU145 cells

M Enomoto, M Utsumi, MK Park

ENDOCRINOLOGY, 147(1) 530-542, Jan, 2006 Peer-reviewed
The mouse ortholog of EFHC1 implicated in juvenile myoclonic epilepsy is an axonemal protein widely conserved among organisms with motile cilia and flagella

T Ikeda, K Ikeda, M Enomoto, MK Park, M Hirono, R Kamiya

FEBS LETTERS, 579(3) 819-822, Jan, 2005 Peer-reviewed
GnRH as a cell proliferation regulator: Mechanism of action and evolutionary implications

M Enomoto, MK Park

ZOOLOGICAL SCIENCE, 21(10) 1005-1013, Oct, 2004 Peer-reviewed
Human type II GnRH receptor mediates effects of GnRH on cell proliferation

M Enomoto, D Endo, S Kawashima, MK Park

ZOOLOGICAL SCIENCE, 21(7) 763-770, Jul, 2004 Peer-reviewed

Misc.

Themes and Variations in Endoplasmic Reticulum Calcium Release Channels: Structure and Function

ENOMOTO MASAHIRO, ISHIYAMA NOBORU, SEO MIN-DUK, AMADOR FERNANDO J, STATHOPULOS, PETER B, IKURA MITSUHIKO

生物物理, 52(6) 266-271 (J-STAGE)-271, 2012

Professional Memberships

Research Projects

Study on the channel-gating mechanism of the inositol-trisphosphate receptor

Grants-in-Aid for Scientific Research(若手研究(B)), 若手研究(B), Ministry of Education, Culture, Sports, Science and Technology, 2008 - 2009

Masahiro ENOMOTO