Mitsuhiro Hashimoto

J-GLOBAL         Last updated: Jun 21, 2019 at 13:35
 
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Name
Mitsuhiro Hashimoto
E-mail
hasimotofmu.ac.jp
URL
http://www.researcherid.com/rid/G-1981-2010
Affiliation
Fukushima Medical University
ORCID ID
0000-0002-8751-4068

Profile

I find that an adenoviral vector can introduce a foreign gene into neurons in a neuronal birthdate specific manner. The nature of an adenoviral vector is very useful for stadying the neuronal development and function, because we can examine and modify a subet of neurons that share the same birthdate. Using the adenoviral vector system, I would like to examine the link between the neuronal birthdate and the neuronal function.
 Using an adenoviral vector, I label Purkinje cells (PCs) born at embryonic day (E)10.5, E11.5, and E12.5 and trace their fated positions in the mouse cerebellum. As a result, I find that each cohort of birthdate-related PCs forms longitudinal compartments in the cerebellum, and furthermore, these compartments formed by each cohort of birthdate-related PCs correlate strikingly with olivocerebellar projection. It suggests that there is close correlation between birthdate of PCs and the formation of cerebellar neuronal network. I would like to examine the correlation between the neuronal birthdates of PCs and cerebellar functions.

My ResearcherID: http://www.researcherid.com/rid/G-1981-2010
Personal home page: http://www004.upp.so-net.ne.jp/MAK-hashimoto
(Sorry, the personal home page is written in Japanese. I will open the English version of it.)

Academic & Professional Experience

 
Apr 2015
 - 
Today
assistant prof., Dept. of Neuroanatomy and Embryology, Fukushima Med. Univ.I
 
Jul 2011
 - 
Mar 2015
Assistant professor, Department of Anatomy and Cell biology, Nagoya Univ.
 
Jun 2004
 - 
Nov 2011
Unit Leader (PI), RIKEN BSI, Hashimoto Research Unit
 
Nov 1997
 - 
May 2004
Researcher, RIKEN BSI
 
Apr 1996
 - 
Mar 1997
postdoctoral fellowship, RIKEN
 

Published Papers

 
Mitsuhiro Hashimoto, Akihiro Yamanaka, Shigeki Kato, Manabu Tanifuji, Kazuto Kobayashi and Hiroyuki Yaginuma
Frontiers in Neural Circuits   12(6) 1-20   Feb 2018   [Refereed]
Mitsuhiro Hashimoto and Masahiko Hibi
Develop. Growth Differ.   54 373-389   2012   [Refereed][Invited]
Hashimoto, Mitsuhiro; Ito, Rie; Kitamura, Naohito; Hisano, Yasuko
The Journal of Comparative Neurology   520(8) 1702-1720   Apr 2012   [Refereed]
Yamada Y, Michikawa T, Hashimoto M, Horikawa K, Nagai T, Miyawaki A, Hausser M, Mikoshiba K
Frontiers in Cellular Neuroscience   5 18   Sep 2011   [Refereed]

Misc

 
Mechanisms of cerebellar development and differentiation.
Mitsuhiro Hashimoto
Neurological Medicine   78(6) 619-626   Jun 2013   [Invited]
“Cerebellum”
Mitsuhiro Hashimoto
Handbook of Neurochemistry and Molecular Neurobiology: Neural Signaling Mechanisms, Ed. Mikoshiba, K.   19 16-24   2009   [Invited]

Research Grants & Projects

 
Project Year: Apr 2013 - Mar 2016    Investigator(s): Mitsuhiro Hashimoto
National Institute for Physiological Science: General collaborative project
Project Year: Apr 2012 - Mar 2013    Investigator(s): Mitsuhiro Hashimoto
JST: CREST
Project Year: 2004 - 2009    Investigator(s): Hensch, Takao
Strategic Exploitation of Neuro-Genetics for Emergence of the Mind
Bureau of Science and Technology poicy: Funding Program for World-Leading Innovative R&D on Science and Technology (FIIST)
Investigator(s): Okano, Hideyuki