2004年12月
New norditerpenoids with trypanocidal activity from Vitex trifolia
CHEMICAL & PHARMACEUTICAL BULLETIN
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- 巻
- 52
- 号
- 12
- 開始ページ
- 1492
- 終了ページ
- 1494
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1248/cpb.52.1492
- 出版者・発行元
- PHARMACEUTICAL SOC JAPAN
Trypanocidal constituents of the fruits of Vitex trifolia were investigated. Activity-guided isolation of the acetone extract resulted in the isolation of two new norditerpene aldehydes, 1 and 2, together with five known diterpenes: vitexifolin E (3), vitexifolin F (4), vitexilactone (5), 6-acetoxy-9-hydroxy-13(14)-labden-16,15-olide (6), and previtexilactone (7). In vitro minimum lethal concentrations of the isolated compounds against epimastigotes of Trypanosoma cruzi were 11mum (1), 36mum (2),34mum (3),34mum (4), 66mum (5), 66mum (6), and >265mum (7).
- リンク情報
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- DOI
- https://doi.org/10.1248/cpb.52.1492
- J-GLOBAL
- https://jglobal.jst.go.jp/detail?JGLOBAL_ID=200902208312029393
- CiNii Articles
- http://ci.nii.ac.jp/naid/110003665484
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000226646600022&DestApp=WOS_CPL
- ID情報
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- DOI : 10.1248/cpb.52.1492
- ISSN : 0009-2363
- J-Global ID : 200902208312029393
- CiNii Articles ID : 110003665484
- Web of Science ID : WOS:000226646600022