論文

査読有り
2019年2月9日

Leydig cell tumor in an Amur tiger (Panthera tigris altaica).

The Journal of veterinary medical science
  • Risako Kawata
  • ,
  • Tatsuhito Ii
  • ,
  • Tatsuya Hori
  • ,
  • Yukino Machida
  • ,
  • Kazuhiko Ochiai
  • ,
  • Daigo Azakami
  • ,
  • Toshiyuki Ishiwata
  • ,
  • Masaki Michishita

81
2
開始ページ
186
終了ページ
189
記述言語
英語
掲載種別
DOI
10.1292/jvms.18-0573

A 14-year and 8-month-old intact male Amur tiger presented with an enlarged left testis, measuring 5.7 × 5.5 × 4.5 cm. The cut surface was mottled dark red to reddish brown in color. Microscopically, the enlarged left testis comprised round or polygonal neoplastic cells arranged in a diffuse sheet pattern. These neoplastic cells had a hyperchromatic nucleus and an abundant eosinophilic cytoplasm. Immunohistochemically, these neoplastic cells were positive for vimentin, chromogranin A, synaptophysin, melan-A, inhibin-α, and S100 and negative for desmin and WT-1. Based on these morphological and immunohistochemical findings, the tumor was diagnosed as a Leydig cell tumor.

リンク情報
DOI
https://doi.org/10.1292/jvms.18-0573
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/30541983
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395220