論文

査読有り
2019年7月11日

Malignant rhabdoid tumor of the musk gland and systemic T-cell lymphoma in a masked palm civet (Paguma larvata).

The Journal of veterinary medical science
  • Yukino Machida
  • ,
  • Masaki Michishita
  • ,
  • Hisashi Yoshimura
  • ,
  • Takuya Kato
  • ,
  • Shin-Ichi Hayama
  • ,
  • Kimimasa Takahashi

81
7
開始ページ
975
終了ページ
979
記述言語
英語
掲載種別
DOI
10.1292/jvms.18-0616

A 21-year-old male masked palm civet died after 2 months of continuous abdominal distention and poor appetite. Grossly, both musk glands were markedly swelled. Microscopically, round, polygonal and spindle neoplastic cells proliferated diffusely in the right musk gland and a metastatic focus was observed in the lung. The neoplastic cells had abundant cytoplasm with faintly eosinophilic inclusions that ultrastructurally corresponded to whorl aggregates of intermediate filaments. Immunohistochemically, these cells were positive for vimentin, cytokeratins and glial fibrillary acidic protein and negative for desmin. Based on these findings, the tumor was diagnosed as malignant rhabdoid tumor. Papillary adenoma was seen in the opposite musk gland. T-cell lymphoma of the lymph nodes, small intestine and liver was considered as the cause of death.

リンク情報
DOI
https://doi.org/10.1292/jvms.18-0616
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/31092741
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656805