論文

査読有り 国際誌
2019年3月

Clinical Safety and Utility of Pediatric Balloon-assisted Enteroscopy: A Multicenter Prospective Study in Japan.

Journal of pediatric gastroenterology and nutrition
  • Shin-Ichiro Hagiwara
  • ,
  • Takahiro Kudo
  • ,
  • Fumihiko Kakuta
  • ,
  • Mikihiro Inoue
  • ,
  • Koji Yokoyama
  • ,
  • Shuichiro Umetsu
  • ,
  • Itaru Iwama
  • ,
  • Toshifumi Yodoshi
  • ,
  • Maiko Tatsuki
  • ,
  • Toshiaki Shimizu
  • ,
  • Yoshiko Nakayama

68
3
開始ページ
306
終了ページ
310
記述言語
英語
掲載種別
DOI
10.1097/MPG.0000000000002181

OBJECTIVES: The benefit of balloon-assisted enteroscopy (BAE) had been recently documented in pediatric patients, but previous reports are based on single institution experiences. We evaluated the feasibility of pediatric BAE in 8 tertiary referral hospitals throughout Japan. METHODS: This was a prospective, multi-institutional study. Patients younger than 18 years were enrolled between April 2014 and March 2017 to undergo double-balloon or single-balloon enteroscopy. Data were collected prospectively using a standardized questionnaire. RESULTS: We enrolled 79 pediatric patients (96 procedures, 70 boys, 26 girls; median age 12.7 years, range 1-17 years). Antegrade (oral-route) BAE was performed in 20 procedures (lowest body weight 12.9 kg, youngest age 3.7 years), and retrograde (anal-route) BAE in 76 (lowest body weight 10.8 kg, youngest age 1.6 years). Severe adverse events were associated with BAE in 2 patients: 1 with hemorrhage due to polypectomy and 1 with pancreatitis after double-balloon endoscopic retrograde cholangioscopy. No intestinal perforation was reported. Procedure duration of oral-route BAE for diagnosis was significantly longer than anal-route for diagnosis (P < 0.001). The overall diagnostic yield for rectal bleeding/positive fecal occult blood test and abdominal pain was 48%. Among 40 patients referred for diagnosis who did not undergo capsule endoscopy, diagnoses were confirmed in 17 (42.5%) patients after BAE. CONCLUSIONS: This prospective multicenter observational study documents the efficacy of BAE in pediatric patients.

リンク情報
DOI
https://doi.org/10.1097/MPG.0000000000002181
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/30444835

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