2014年1月
Differential involvement of two cortical masticatory areas in submandibular salivary secretion in rats
BRAIN RESEARCH
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- 巻
- 1543
- 号
- 開始ページ
- 200
- 終了ページ
- 208
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/j.brainres.2013.11.024
- 出版者・発行元
- ELSEVIER SCIENCE BV
To evaluate the role of the masticatory area in the cerebral cortex in the masticatory-salivary reflex, we investigated submandibular salivary secretion, jaw-movement trajectory and electromyographic activity of the jaw-opener (digastric) and jaw-closer (masseter) muscles evoked by repetitive electrical stimulation of the cortical masticatory area in anesthetized rats. Rats have two cortical masticatory areas: the anterior area (A-area) in the orofacial motor cortex, and the posterior area (P-area) in the insular cortex. Our defined P-area extended more caudally than the previous reported one. P-area stimulation induced vigorous salivary secretion (about 20 mu l/min) and rhythmical jaw movements (3-4 Hz) resembling masticatory movements. Salivary flow persisted even after minimizing jaw movements by curarization. A-area stimulation induced small and fast rhythmical jaw movements (6-8 Hz) resembling licking of solutions, but not salivary secretion. These findings suggest that P-area controls salivary secretion as well as mastication, and may be involved in the masticatory-salivary reflex. (C) 2013 Elsevier B.V. All rights reserved.
- リンク情報
- ID情報
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- DOI : 10.1016/j.brainres.2013.11.024
- ISSN : 0006-8993
- eISSN : 1872-6240
- PubMed ID : 24309141
- Web of Science ID : WOS:000330491300023