Jan, 2008
Antinematodal activities of ingenane diterpenes from Euphorbia kansui and their derivatives against the pine wood nematode (Bursaphelenchus xylophilus)
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
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- Volume
- 63
- Number
- 1-2
- First page
- 59
- Last page
- 65
- Language
- English
- Publishing type
- Research paper (scientific journal)
- Publisher
- VERLAG Z NATURFORSCH
Under the bioassay-guided method, two diterpenes, 3-O-(2",3"-dimethylbutanoyl)-13-O-dodecanoylingenol (1) and 3-O-(2",3"-dimethylbutanoyl)-13-O-decanoylingenol (2) isolated from Euphorbia kansui, showed a pronounced antinematodal activity against the nematode Bursaphelenchus xylophilus at the same minimum effective dose (MED) of 5 mu g per cotton ball and still displayed antinematodal activity at a dose of 2.5 mu g per cotton ball. Compounds 3-6 were obtained, and the structure of the new compound 6 was elucidated based on 1D- and 2D-NMR analyses and physicochemical data. Preliminary structure-biological activity relationships of ingenane-type compounds were deduced.
- Link information
- ID information
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- ISSN : 0939-5075
- Web of Science ID : WOS:000254633400011