Oct, 2008
Synthesis and biological evaluation of alkoxycoumarins as novel nematicidal constituents
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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- Volume
- 18
- Number
- 20
- First page
- 5614
- Last page
- 5617
- Language
- English
- Publishing type
- Research paper (scientific journal)
- DOI
- 10.1016/j.bmcl.2008.08.102
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
We synthesized all of the monomethoxycoumarins, 5-alkoxycoumarins and their derivatives, and investigated their nematicidal activity against the phytopathogenic nematode, Bursaphelenchus xylophilus. Among the compounds, 5-ethoxycoumarin showed the highest nematicidal activity. Furthermore, 5-ethoxycoumarin was comparatively harmless against both the brine shrimps, Artemia salina, and the Japanese killifish, Oryzias latipes. (C) 2008 Elsevier Ltd. All rights reserved.
- Link information
- ID information
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- DOI : 10.1016/j.bmcl.2008.08.102
- ISSN : 0960-894X
- Web of Science ID : WOS:000259972800062