山崎 美和（若林美和）

Complex intrinsic abnormalities in osteoblast lineage cells of X-linked hypophosphatemia: Analysis of human iPS cell models generated by CRISPR/Cas9-mediated gene ablation. 

Bone 181 117044-117044 2024年4月  

A unique case of childhood hypophosphatasia caused by a novel heterozygous 51-bp in-frame deletion in the ALPL gene. 

Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology 32(3) 180-187 2023年  

Extracellular Phosphate, Inflammation and Cytotoxicity. 

Advances in experimental medicine and biology 1362 15-25 2022年  

Osteocytes and the pathogenesis of hypophosphatemic rickets. 

Frontiers in endocrinology 13 1005189-1005189 2022年  

Clonal osteoblastic cell lines with CRISPR/Cas9-mediated ablation of Pit1 or Pit2 show enhanced mineralization despite reduced osteogenic gene expression. 

Bone 151 116036-116036 2021年10月  

Hypophosphatasia in Japan: ALPL Mutation Analysis in 98 Unrelated Patients. 

Calcified tissue international 106(3) 221-231 2020年3月  

CREB activation in hypertrophic chondrocytes is involved in the skeletal overgrowth in epiphyseal chondrodysplasia Miura type caused by activating mutations of natriuretic peptide receptor B. 

Human molecular genetics 28(7) 1183-1198 2019年4月1日  

Intestinal clock system regulates skeletal homeostasis. 

JCI insight 4(5) 2019年3月7日  

Phosphate as a Signaling Molecule and Its Sensing Mechanism. 

Physiological reviews 98(4) 2317-2348 2018年10月1日  

Extracellular Phosphate Induces the Expression of Dentin Matrix Protein 1 Through the FGF Receptor in Osteoblasts. 

Journal of cellular biochemistry 118(5) 1151-1163 2017年5月  

Interleukin-1-induced acute bone resorption facilitates the secretion of fibroblast growth factor 23 into the circulation. 

Journal of bone and mineral metabolism 33(3) 342-54 2015年5月  

Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of Hyp mice. 

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 29(7) 1627-38 2014年7月  

Dysregulated gene expression in the primary osteoblasts and osteocytes isolated from hypophosphatemic Hyp mice. 

PloS one 9(4) e93840 2014年  

Sodium-coupled neutral amino acid transporter 4 functions as a regulator of protein synthesis during liver development. 

Hepatology research : the official journal of the Japan Society of Hepatology 43(11) 1211-23 2013年11月  

FGF23 suppresses chondrocyte proliferation in the presence of soluble α-Klotho both in vitro and in vivo. 

The Journal of biological chemistry 288(4) 2414-27 2013年1月25日  

Both FGF23 and extracellular phosphate activate Raf/MEK/ERK pathway via FGF receptors in HEK293 cells. 

Journal of cellular biochemistry 111(5) 1210-21 2010年12月1日  

Signaling of extracellular inorganic phosphate up-regulates cyclin D1 expression in proliferating chondrocytes via the Na+/Pi cotransporter Pit-1 and Raf/MEK/ERK pathway. 

Bone 47(5) 938-47 2010年11月  

Czech dysplasia occurring in a Japanese family. 

American journal of medical genetics. Part A 149A(10) 2285-9 2009年10月  

Multiple enhancer regions located at significant distances upstream of the transcriptional start site mediate RANKL gene expression in response to 1,25-dihydroxyvitamin D3. 

The Journal of steroid biochemistry and molecular biology 103(3-5) 430-4 2007年3月