原田美由紀 (Miyuki Harada) - マイポータル

基本情報

所属: 東京大学産婦人科

学位: 医学博士(2007年3月東京大学)

研究者番号: 70451812
J-GLOBAL ID: 201801005743539389
researchmap会員ID: B000306237

研究キーワード

研究分野

経歴

2020年4月 - 現在

東京大学, 産婦人科, 准教授
2016年12月 - 2020年3月

東京大学, 産婦人科, 講師
2009年10月 - 2016年11月

東京大学, 産婦人科, 助教
2008年10月 - 2009年9月

ミシガン大学, 産婦人科/生化学教室, 日本学術振興会若手研究者International Training Program 研究員
2008年5月 - 2008年9月

東京大学, 産婦人科, 助教
2007年4月 - 2008年4月

東京大学, 産婦人科, 医員

学歴

- 2007年3月

東京大学大学院, 医学系研究科, 生殖発達加齢医学専攻
- 2000年3月

東京大学, 医学部, 医学科

主要な委員歴

もっとみる

受賞

主要な論文

184

134

Temporal relationship between alterations in the gut microbiome and the development of polycystic ovary syndrome‐like phenotypes in prenatally androgenized female mice

Akari Kusamoto, Miyuki Harada, Jerilee M. K. Azhary, Chisato Kunitomi, Emi Nose, Hiroshi Koike, Zixin Xu, Yoko Urata, Tetsuaki Kaku, Nozomi Takahashi …

The FASEB Journal 35(11) 2021年11月査読有り責任著者
64

Pregnancy outcomes in children, adolescents, and young adults that survived cancer: A nationwide survey in Japan

Toshiaki Yasuoka, Noriyuki Iwama, Kuniaki Ota, Miyuki Harada, Junichi Hasegawa, Nobuo Yaegashi, Takashi Sugiyama, Nao Suzuki, Yutaka Osuga

Journal of Obstetrics and Gynaecology Research 47(9) 3352-3361 2021年9月査読有り責任著者
Fertility preservation in patients receiving gonadotoxic therapies for systemic autoimmune diseases in Japan.

Yumi Tsuchida, Miyuki Harada, Hirofumi Shoda, Ayane Goto, Nao Suzuki, Atsuko Murashima, Yutaka Osuga, Keishi Fujio

Modern rheumatology 31(5) 1004-1009 2021年9月査読有り
151

Induction of aryl hydrocarbon receptor in granulosa cells by endoplasmic reticulum stress contributes to pathology of polycystic ovary syndrome.

Chisato Kunitomi, Miyuki Harada, Akari Kusamoto, Jerilee Mk Azhary, Emi Nose, Hiroshi Koike, Zixin Xu, Yoko Urata, Nozomi Takahashi, Osamu Wada-Hiraike …

Molecular human reproduction 27(3) 2021年2月27日査読有り責任著者
50

National survey of primary amenorrhea and relevant conditions in Japan

Hirofumi Haraguchi, Miyuki Harada, Kenichi Kashimada, Reiko Horikawa, Hideya Sakakibara, Makio Shozu, Tomoyuki Fujii, Yutaka Osuga, Koji Kugu

Journal of Obstetrics and Gynaecology Research 47(2) 774-777 2021年2月査読有り責任著者
179

Endoplasmic reticulum stress: a key regulator of the follicular microenvironment in the ovary.

Miyuki Harada, Nozomi Takahashi, Jerilee Mk Azhary, Chisato Kunitomi, Tomoyuki Fujii, Yutaka Osuga

Molecular human reproduction 27(1) 2021年1月22日査読有り筆頭著者責任著者
76

Does polycystic ovary syndrome independently affect oncologic and reproductive outcomes in patients with endometrial cancer receiving fertility-sparing treatment?

Miyuki Harada, Yutaka Osuga

Journal of Gynecologic Oncology 32(5) 2021年招待有り筆頭著者
113

Androgens Increase Accumulation of Advanced Glycation End Products in Granulosa Cells by Activating ER Stress in PCOS

Jerilee M K Azhary, Miyuki Harada, Chisato Kunitomi, Akari Kusamoto, Nozomi Takahashi, Emi Nose, Nagisa Oi, Osamu Wada-Hiraike, Yoko Urata, Tetsuya Hirata …

Endocrinology 161(2) 2020年2月1日査読有り責任著者
119

Preclinical validation of the new vitrification device possessing a feature of absorbing excess vitrification solution for the cryopreservation of human embryos.

Nozomi Takahashi, Miyuki Harada, Nagisa Oi, Gentaro Izumi, Kenji Momozawa, Atsushi Matsuzawa, Yukio Tokunaga, Tetsuya Hirata, Tomoyuki Fujii, Yutaka Osuga

The journal of obstetrics and gynaecology research 46(2) 302-309 2020年2月査読有り責任著者
Activation of endoplasmic reticulum stress mediates oxidative stress-induced apoptosis of granulosa cells in ovaries affected by endometrioma.

Chisato Kunitomi, Miyuki Harada, Nozomi Takahashi, Jerilee M K Azhary, Akari Kusamoto, Emi Nose, Nagisa Oi, Arisa Takeuchi, Osamu Wada-Hiraike, Tetsuya Hirata …

Molecular human reproduction 26(1) 40-52 2020年1月1日査読有り責任著者
Accumulation of advanced glycation end products in follicles is associated with poor oocyte developmental competence

Nozomi Takahashi, Miyuki Harada, Jerilee M K Azhary, Chisato Kunitomi, Emi Nose, Hiromi Terao, Hiroshi Koike, Osamu Wada-Hiraike, Tetsuya Hirata, Yasushi Hirota …

Molecular Human Reproduction 25(11) 684-694 2019年11月30日査読有り責任著者
A Japanese nationwide survey on the cryopreservation of embryos, oocytes and ovarian tissue for cancer patients.

Yuko Sanada, Miyuki Harada, Chisato Kunitomi, Mayuko Kanatani, Gentaro Izumi, Tetsuya Hirata, Tomoyuki Fujii, Nao Suzuki, Ken-Ichirou Morishige, Daisuke Aoki …

The journal of obstetrics and gynaecology research 45(10) 2021-2028 2019年10月査読有り責任著者
Fertility preservation for female cancer patients.

Miyuki Harada, Yutaka Osuga

International journal of clinical oncology 24(1) 28-33 2019年1月査読有り招待有り筆頭著者
Endoplasmic Reticulum Stress Activated by Androgen Enhances Apoptosis of Granulosa Cells via Induction of Death Receptor 5 in PCOS.

Jerilee M K Azhary, Miyuki Harada, Nozomi Takahashi, Emi Nose, Chisato Kunitomi, Hiroshi Koike, Tetsuya Hirata, Yasushi Hirota, Kaori Koga, Osamu Wada-Hiraike …

Endocrinology 160(1) 119-132 2019年1月1日査読有り責任著者
Factors associated with successful pregnancy in women of late reproductive age with uterine fibroids who undergo embryo cryopreservation before surgery.

Nozomi Takahashi, Miyuki Harada, Ryosuke Tanabe, Akane Takayanagi, Gentaro Izumi, Nagisa Oi, Tetsuya Hirata, Osamu Wada-Hiraike, Tomoyuki Fujii, Yutaka Osuga

The journal of obstetrics and gynaecology research 44(10) 1956-1962 2018年10月査読有り責任著者
Activation of Endoplasmic Reticulum Stress in Granulosa Cells from Patients with Polycystic Ovary Syndrome Contributes to Ovarian Fibrosis.

Nozomi Takahashi, Miyuki Harada, Yasushi Hirota, Emi Nose, Jerilee Mk Azhary, Hiroshi Koike, Chisato Kunitomi, Osamu Yoshino, Gentaro Izumi, Tetsuya Hirata …

Scientific reports 7(1) 10824-10824 2017年9月7日査読有り責任著者
A Potential Role for Endoplasmic Reticulum Stress in Progesterone Deficiency in Obese Women.

Nozomi Takahashi, Miyuki Harada, Yasushi Hirota, Lin Zhao, Jerilee M K Azhary, Osamu Yoshino, Gentaro Izumi, Tetsuya Hirata, Kaori Koga, Osamu Wada-Hiraike …

Endocrinology 158(1) 84-97 2017年1月1日査読有り責任著者
Where are oncofertility and fertility preservation treatments heading in 2016?

Miyuki Harada, Yutaka Osuga

Future oncology (London, England) 12(20) 2313-21 2016年10月査読有り招待有り筆頭著者
A potential role of endoplasmic reticulum stress in development of ovarian hyperstimulation syndrome.

Nozomi Takahashi, Miyuki Harada, Yasushi Hirota, Lin Zhao, Osamu Yoshino, Yoko Urata, Gentaro Izumi, Masashi Takamura, Tetsuya Hirata, Kaori Koga …

Molecular and cellular endocrinology 428(C) 161-9 2016年6月15日査読有り責任著者
Vaginal Stenosis After Gonadotropin-Releasing Hormone Agonist Therapy During Treatment for Acute Lymphoblastic Leukemia.

Masakazu Sato, Miyuki Harada, Hajime Oishi, Osamu Wada-Hiraike, Tetsuya Hirata, Kazunori Nagasaka, Kaori Koga, Tomoyuki Fujii, Yutaka Osuga

Journal of lower genital tract disease 20(2) e11-3-e13 2016年4月査読有り責任著者
Evidence of the activation of unfolded protein response in granulosa and cumulus cells during follicular growth and maturation.

Miyuki Harada, Emi Nose, Nozomi Takahashi, Yasushi Hirota, Tetsuya Hirata, Osamu Yoshino, Kaori Koga, Tomoyuki Fujii, Yutaka Osuga

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 31(10) 783-7 2015年10月査読有り筆頭著者責任著者
Laparoscopic excision of ovarian endometrioma does not exert a qualitative effect on ovarian function: insights from in vitro fertilization and single embryo transfer cycles.

Miyuki Harada, Nozomi Takahashi, Tetsuya Hirata, Kaori Koga, Tomoyuki Fujii, Yutaka Osuga

Journal of assisted reproduction and genetics 32(5) 685-9 2015年5月査読有り筆頭著者責任著者
Molecular regulation of gonadotropin receptor expression: Relationship to sterol metabolism

K. M. J. Menon, B. Menon, L. Wang, T. Gulappa, M. Harada

MOLECULAR AND CELLULAR ENDOCRINOLOGY 329(1-2) 26-32 2010年11月査読有り
Expression of vascular endothelial growth factor A during ligand-induced down-regulation of luteinizing hormone receptor in the ovary

M. Harada, H. Peegel, K. M. J. Menon

MOLECULAR AND CELLULAR ENDOCRINOLOGY 328(1-2) 28-33 2010年10月査読有り筆頭著者
Inhibitory effect of valproic acid on ovarian androgen biosynthesis in rat theca-interstitial cells.

Senait Fisseha, Roberto Towns, Miyuki Harada, Helle Peegel, K M J Menon

Endocrine 37(1) 187-93 2010年2月査読有り