水品佳子 (Yoshiko Mizushina) - マイポータル

基本情報

所属: 自治医科大学医学部臨床検査医学講座講師 (学内講師)

J-GLOBAL ID: 202001016285502357
researchmap会員ID: R000006819

研究キーワード

急性肺傷害

研究分野

ライフサイエンス / 呼吸器内科学 /

論文

Low Potassium Triggers Tubular Epithelial NLR Family Pyrin Domain-Containing 3/Apoptosis-Associated Speck-Like Protein-Containing a CARD–Driven Kidney Inflammation Independently of Inflammasomes

Satoko Komori, Takanori Komada, Takayoshi Matsumura, Tadayoshi Karasawa, Yutaka Miura, Chintogtokh Baatarjav, Yoshitaka Gunji, Hidetoshi Aizawa, Yoshiko Mizushina, Noriyoshi Fukushima …

The American Journal of Pathology 195(12) 2336-2355 2025年12月
IL-33-primed NLRP3 inflammasome in basophils drives IL-1β production and initiates atopic dermatitis inflammation

Yoshitaka Gunji, Takayoshi Matsumura, Tadayoshi Karasawa, Takanori Komada, Chintogtokh Baatarjav, Satoko Komori, Hidetoshi Aizawa, Yoshiko Mizushina, Hidetoshi Tsuda, Kensuke Miyake …

Cell Death Discovery 11(1) 2025年7月27日
Caspase-11 deficiency attenuates neutrophil recruitment into the atherosclerotic lesion in apolipoprotein E-deficient mice.

Tadayoshi Karasawa, Takanori Komada, Chintogtokh Baatarjav, Emi Aizawa, Yoshiko Mizushina, Kenta Fujimura, Yoshitaka Gunji, Satoko Komori, Hidetoshi Aizawa, Cantona Billton Jing Tao …

Biochemical and biophysical research communications 686 149158-149158 2023年12月17日
NLRP3 inflammasome-driven IL-1β and IL-18 contribute to lipopolysaccharide-induced septic cardiomyopathy.

Kenta Fujimura, Tadayoshi Karasawa, Takanori Komada, Naoya Yamada, Yoshiko Mizushina, Chintogtokh Baatarjav, Takayoshi Matsumura, Kinya Otsu, Norihiko Takeda, Hiroaki Mizukami …

Journal of molecular and cellular cardiology 180 58-68 2023年7月
Cryo-sensitive aggregation triggers NLRP3 inflammasome assembly in cryopyrin-associated periodic syndrome.

Tadayoshi Karasawa, Takanori Komada, Naoya Yamada, Emi Aizawa, Yoshiko Mizushina, Sachiko Watanabe, Chintogtokh Baatarjav, Takayoshi Matsumura, Masafumi Takahashi

eLife 11 2022年5月26日
Immunoglobulin G4-related Pleuritis Complicated with Minimal Change Disease.

Yoshiko Mizushina, Jun Shiihara, Motoko Nomura, Hiromitsu Ohta, Fumiyoshi Ohyanagi, Yoshiyuki Morishita, Hiroyoshi Tsubochi, Akira Tanaka, Yasuhiro Yamaguchi

Internal medicine (Tokyo, Japan) 61(5) 723-728 2022年3月1日
Dramatic response to alectinib in a patient with ALK-rearranged squamous cell lung cancer.

Jun Shiihara, Fumiyoshi Ohyanagi, Hikari Amari, Minemichi Toda, Hiroki Tahara, Motoi Yuzawa, Yuki Maeda, Motoko Nomura, Yoshiko Mizushina, Yoshiaki Nagai …

Thoracic cancer 12(17) 2420-2423 2021年9月
Clinical case of lung spindle cell carcinoma markedly responsive to pembrolizumab.

Yoshiko Mizushina, Fumiyoshi Ohyanagi, Jun Shiihara, Motoko Nomura, Hiromitsu Ohta, Hisashi Oshiro, Hiroyoshi Tsubochi, Gen Kusaka, Yasuhiro Yamaguchi

Thoracic cancer 12(16) 2279-2282 2021年8月
Inhibitory effects of somatostatin analogue in bleomycin-induced pulmonary fibrosis.

Tatsuya Hosono, Masashi Bando, Yoshiko Mizushina, Masafumi Sata, Koichi Hagiwara, Yukihiko Sugiyama

Experimental lung research 47(6) 280-288 2021年
Pulmonary mucoepidermoid carcinoma arising in a patient with Kartagener syndrome.

Yoshiaki Nagai, Nobuyuki Koyama, Yuki Iwai, Hiroyoshi Tsubochi, Masahiro Hiruta, Yoshiko Mizushina, Shinichiro Koyama, Yuichi Ishikawa, Koichi Hagiwara

BMC pulmonary medicine 20(1) 93-93 2020年4月16日
Inflammasome-Independent and Atypical Processing of IL-1β Contributes to Acid Aspiration-Induced Acute Lung Injury.

Yoshiko Mizushina, Tadayoshi Karasawa, Kenichi Aizawa, Hiroaki Kimura, Sachiko Watanabe, Ryo Kamata, Takanori Komada, Naoko Mato, Tadashi Kasahara, Shinichiro Koyama …

Journal of immunology (Baltimore, Md. : 1950) 203(1) 236-246 2019年7月1日
Interaction of Neutrophils with Macrophages Promotes IL-1β Maturation and Contributes to Hepatic Ischemia-Reperfusion Injury.

Ai Sadatomo, Yoshiyuki Inoue, Homare Ito, Tadayoshi Karasawa, Hiroaki Kimura, Sachiko Watanabe, Yoshiko Mizushina, Jun Nakamura, Ryo Kamata, Tadashi Kasahara …

Journal of immunology (Baltimore, Md. : 1950) 199(9) 3306-3315 2017年11月1日
NLRP3 Deficiency Reduces Macrophage Interleukin-10 Production and Enhances the Susceptibility to Doxorubicin-induced Cardiotoxicity.

Motoi Kobayashi, Fumitake Usui, Tadayoshi Karasawa, Akira Kawashima, Hiroaki Kimura, Yoshiko Mizushina, Koumei Shirasuna, Hiroaki Mizukami, Tadashi Kasahara, Naoyuki Hasebe …

Scientific reports 6 26489-26489 2016年5月26日
Immunoproteasome subunit LMP7 Deficiency Improves Obesity and Metabolic Disorders.

Hiroaki Kimura, Fumitake Usui, Tadayoshi Karasawa, Akira Kawashima, Koumei Shirasuna, Yoshiyuki Inoue, Takanori Komada, Motoi Kobayashi, Yoshiko Mizushina, Tadashi Kasahara …

Scientific reports 5 15883-15883 2015年10月30日
Role of NLRP3 Inflammasomes for Rhabdomyolysis-induced Acute Kidney Injury.

Takanori Komada, Fumitake Usui, Akira Kawashima, Hiroaki Kimura, Tadayoshi Karasawa, Yoshiyuki Inoue, Motoi Kobayashi, Yoshiko Mizushina, Tadashi Kasahara, Shun'ichiro Taniguchi …

Scientific reports 5 10901-10901 2015年6月5日
NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of interleukin-1β.

Yoshiko Mizushina, Koumei Shirasuna, Fumitake Usui, Tadayoshi Karasawa, Akira Kawashima, Hiroaki Kimura, Motoi Kobayashi, Takanori Komada, Yoshiyuki Inoue, Naoko Mato …

The Journal of biological chemistry 290(8) 5065-5077 2015年2月20日
Oligomerized CARD16 promotes caspase-1 assembly and IL-1β processing.

Tadayoshi Karasawa, Akira Kawashima, Fumitake Usui, Hiroaki Kimura, Koumei Shirasuna, Yoshiyuki Inoue, Takanori Komada, Motoi Kobayashi, Yoshiko Mizushina, Junji Sagara …

FEBS open bio 5 348-56 2015年
Interferon-tau attenuates uptake of nanoparticles and secretion of interleukin-1β in macrophages.

Kyoko Hara, Koumei Shirasuna, Fumitake Usui, Tadayoshi Karasawa, Yoshiko Mizushina, Hiroaki Kimura, Akira Kawashima, Akihide Ohkuchi, Shuichi Matsuyama, Koji Kimura …

PloS one 9(12) e113974 2014年
A rare case of asymptomatic diffuse pulmonary ossification detected during a routine health examination.

Yoshiko Mizushina, Masashi Bando, Tatsuya Hosono, Naoko Mato, Takakiyo Nakaya, Hideaki Yamasawa, Mitsugu Hironaka, Akira Tanaka, Yukihiko Sugiyama

Internal medicine (Tokyo, Japan) 51(20) 2923-7 2012年
Clinical features of lymphangioleiomyomatosis complicated by renal angiomyolipomas.

Yoshiko Mizushina, Masashi Bando, Tatsuya Hosono, Naoko Mato, Takakiyo Nakaya, Yoshikazu Ishii, Hideaki Yamasawa, Yukihiko Sugiyama

Internal medicine (Tokyo, Japan) 50(4) 285-9 2011年

もっとみる

共同研究・競争的資金等の研究課題

急性肺傷害における血清アミロイドAとインフラマソームの役割の解明

日本学術振興会科学研究費助成事業基盤研究(C) 2024年4月 - 2027年3月

水品佳子
急性肺傷害における炎症性細胞死Pyroptosisの機序と役割の解明

日本学術振興会科学研究費助成事業若手研究 2022年4月 - 2024年3月

水品佳子
肺線維症における無菌性炎症の分子基盤の解明

日本学術振興会科学研究費助成事業若手研究 2020年4月 - 2022年3月

水品佳子
急性肺傷害における無菌性炎症の分子基盤の解明

日本学術振興会科学研究費助成事業研究活動スタート支援 2016年8月 - 2018年3月

水品佳子, 高橋将文