Motohiko Kadoki

Profile Information

J-GLOBAL ID: 201701000713321223
researchmap Member ID: B000276907

Research Interests

Research Areas

Papers

Blocking Dectin-1 prevents colorectal tumorigenesis by suppressing prostaglandin E2 production in myeloid-derived suppressor cells and enhancing IL-22 binding protein expression.

Ce Tang, Haiyang Sun, Motohiko Kadoki, Wei Han, Xiaoqi Ye, Yulia Makusheva, Jianping Deng, Bingbing Feng, Ding Qiu, Ying Tan …

Nature communications, 14(1) 1493-1493, Mar 17, 2023
A missense variant in SLC39A8 confers risk for Crohn’s disease by disrupting manganese homeostasis and intestinal barrier integrity

Toru Nakata, Elizabeth A. Creasey, Motohiko Kadoki, Helen Lin, Martin K. Selig, Junmei Yao, Ariel Lefkovith, Mark J. Daly, Daniel B. Graham, Ramnik J. Xavier

Proceedings of the National Academy of Sciences, 117(46) 28930-28938, Nov 17, 2020 Peer-reviewed
Cell Type– and Stimulation-Dependent Transcriptional Programs Regulated by Atg16L1 and Its Crohn's Disease Risk Variant T300A

Mukund Varma, Motohiko Kadoki, Ariel Lefkovith, Kara L. Conway, Kevin Gao, Vishnu Mohanan, Betsabeh Khoramian Tusi, Daniel B. Graham, Isabel J. Latorre, Andrew C. Tolonen …

The Journal of Immunology, 205(2) 414-424, Jul 15, 2020 Peer-reviewed
Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota.

Ce Tang, Shigeru Kakuta, Kenji Shimizu, Motohiko Kadoki, Tomonori Kamiya, Tomoyuki Shimazu, Sachiko Kubo, Shinobu Saijo, Harumichi Ishigame, Susumu Nakae …

Nature immunology, 19(7) 755-765, Jul, 2018 Peer-reviewed
β-Glucans in food modify colonic microflora by inducing antimicrobial protein, calprotectin, in a Dectin-1-induced-IL-17F-dependent manner

T. Kamiya, C. Tang, M. Kadoki, K. Oshima, M. Hattori, S. Saijo, Y. Adachi, N. Ohno, Y. Iwakura

Mucosal Immunology, 11(3) 763-773, May 1, 2018 Peer-reviewed
Organism-Level Analysis of Vaccination Reveals Networks of Protection across Tissues

Motohiko Kadoki, Ashwini Patil, Cornelius C. Thaiss, Donald J. Brooks, Surya Pandey, Deeksha Deep, David Alvarez, Ulrich H. von Andrian, Amy J. Wagers, Kenta Nakai …

CELL, 171(2) 398-+, Oct, 2017 Peer-reviewed
Inhibition of Dectin-1 Signaling Ameliorates Colitis by Inducing Lactobacillus-Mediated Regulatory T Cell Expansion in the Intestine

Ce Tang, Tomonori Kamiya, Yang Liu, Motohiko Kadoki, Shigeru Kakuta, Kenshiro Oshima, Masahira Hattori, Kozue Takeshita, Takanori Kanai, Shinobu Saijo …

CELL HOST & MICROBE, 18(2) 183-197, Aug, 2015 Peer-reviewed
Transgenic expression of the human LEDGF/p75 gene relieves the species barrier against HIV-1 infection in mouse cells

Takuya Tada, Motohiko Kadoki, Yang Liu, Kenzo Tokunaga, Yoichiro Iwakura

FRONTIERS IN MICROBIOLOGY, 4(DEC) 377, Dec, 2013 Peer-reviewed
IL-17F, rather than IL-17A promotes CD4+T cell activation and Th1-type immunity

Tang Ce, Kakuta Shigeru, Kadoki Motohiko, Iwakura Voichiro

Cytokine, 56(1) 19-20, 2011 Peer-reviewed
The mechanism of LPS-induced HIV type I activation in transgenic mouse macrophages

Motohiko Kadoki, Byung-Il Choi, Yoichiro Iwakura

INTERNATIONAL IMMUNOLOGY, 22(6) 469-478, Jun, 2010 Peer-reviewed
Differential Roles of Interleukin-17A and-17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses

Harumichi Ishigame, Shigeru Kakuta, Takeshi Nagai, Motohiko Kadoki, Aya Nambu, Yutaka Komiyama, Noriyuki Fujikado, Yuko Tanahashi, Aoi Akitsu, Hayato Kotaki …

IMMUNITY, 30(1) 108-119, Jan, 2009 Peer-reviewed
Nuclear import of the preintegration complex is blocked upon infection by human immunodeficiency virus type 1 in mouse cells

Naomi Tsurutani, Jiro Yasuda, Naoki Yamamoto, Byung-Il Choi, Motohiko Kadoki, Yoichiro Iwakura

JOURNAL OF VIROLOGY, 81(2) 677-688, Jan, 2007 Peer-reviewed

Misc.

Inhibition of Dectin-1 signaling suppresses colitis by regulating the balance of intestinal microbiota and cellular immunity

Ce Tang, Tomonori Kamiya, Motohiko Kadoki, Yoichiro Iwakura

CYTOKINE, 63(3) 303-303, Sep, 2013
IL-22+CD4+T細胞による大腸炎誘導と抑制

角木基彦, 岩倉洋一郎

臨床免疫・アレルギー科, 59(3) 405-410, Mar, 2013
A novel role of Dectin-1 signaling in promoting intestinal inflammation

C. Tang, T. Kamiya, M. Kadoki, Y. Iwakura

CYTOKINE, 59(3) 516-516, Sep, 2012
IL-17と感染防御

角木基彦, 岩倉洋一郎

臨床免疫・アレルギー科, 57(4) 430-436, Apr, 2012
マウスモデルを用いたHIV-1潜伏・再活性化機構の解析

角木基彦, 岩倉洋一郎

日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 80回・30回 4T23-3, Nov, 2007

Research Projects

アレルギー応答におけるＣ型レクチンの役割

科学研究費助成事業, 若手研究(B), 日本学術振興会, Apr, 2012 - Mar, 2014

角木基彦

Profile Information

Research Interests

Research Areas

Papers

Misc.

Research Projects

Menu

Coauthors