論文

国際誌
2015年1月16日

Systemic arteriosclerosis and eating behavior in Japanese type 2 diabetic patients with visceral fat accumulation.

Cardiovascular diabetology
  • Shiro Fukuda
  • ,
  • Ayumu Hirata
  • ,
  • Hitoshi Nishizawa
  • ,
  • Hirofumi Nagao
  • ,
  • Susumu Kashine
  • ,
  • Takekazu Kimura
  • ,
  • Kana Inoue
  • ,
  • Yuya Fujishima
  • ,
  • Masaya Yamaoka
  • ,
  • Junji Kozawa
  • ,
  • Tetsuhiro Kitamura
  • ,
  • Tetsuyuki Yasuda
  • ,
  • Norikazu Maeda
  • ,
  • Akihisa Imagawa
  • ,
  • Tohru Funahashi
  • ,
  • Iichiro Shimomura

14
開始ページ
8
終了ページ
8
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1186/s12933-015-0174-7

BACKGROUND: Visceral fat accumulation is a major etiological factor in the progression of type 2 diabetes mellitus and atherosclerosis. We described previously visceral fat accumulation and multiple cardiovascular risk factors in a considerable number of Japanese non-obese subjects (BMI <25 kg/m(2)). Here, we investigated differences in systemic arteriosclerosis, serum adiponectin concentration, and eating behavior in type 2 diabetic patients with and without visceral fat accumulation. METHODS: The study subjects were 75 Japanese type 2 diabetes mellitus (age: 64.8 ± 11.5 years, mean ± SD). Visceral fat accumulation represented an estimated visceral fat area of 100 cm(2) using the bioelectrical impedance analysis method. Subjects were divided into two groups; with (n = 53) and without (n = 22) visceral fat accumulation. Systemic arteriosclerosis was scored for four arteries by ultrasonography. Eating behavior was assessed based on The Guideline for Obesity questionnaire issued by the Japan Society for the Study of Obesity. RESULTS: The visceral fat accumulation (+) group showed significantly higher systemic vascular scores and significantly lower serum adiponectin levels than the visceral fat accumulation (-) group. With respect to the eating behavior questionnaire items, (+) patients showed higher values for the total score and many of the major sub-scores than (-) patients. CONCLUSIONS: Type 2 diabetic patients with visceral fat accumulation showed 1) progression of systemic arteriosclerosis, 2) low serum adiponectin levels, and 3) differences in eating behavior, compared to those without visceral fat accumulation. Taken together, the findings highlight the importance of evaluating visceral fat area in type 2 diabetic patients. Furthermore, those with visceral fat accumulation might need to undergo more intensive screening for systemic arteriosclerosis and consider modifying their eating behaviors.

リンク情報
DOI
https://doi.org/10.1186/s12933-015-0174-7
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/25592402
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301666
ID情報
  • DOI : 10.1186/s12933-015-0174-7
  • PubMed ID : 25592402
  • PubMed Central 記事ID : PMC4301666

エクスポート
BibTeX RIS