Motoko Maekawa

J-GLOBAL         Last updated: Oct 24, 2018 at 12:17
 
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Name
Motoko Maekawa

Research Interests

 
 

Research Areas

 
 

Published Papers

 
Maekawa M, Ohnishi T, Balan S, Hisano Y, Nozaki Y, Ohba H, Toyoshima M, Shimamoto C, Tabata C, Wada Y, Yoshikawa T
Bioscience, biotechnology, and biochemistry   1-9   Sep 2018   [Refereed]
Maekawa M., Watanabe A., Iwayama Y., Kimura T., Hamazaki K., Balan S., Ohba H., Hisano Y., Nozaki Y., Ohnishi T., Toyoshima M., Shimamoto C., Iwamoto K., Bundo M., Osumi N., Takahashi E., Takashima A., Yoshikawa T.
TRANSLATIONAL PSYCHIATRY   7    Sep 2017   [Refereed]
Morimura N, Yasuda H, Yamaguchi K, Katayama KI, Hatayama M, Tomioka NH, Odagawa M, Kamiya A, Iwayama Y, Maekawa M, Nakamura K, Matsuzaki H, Tsujii M, Yamada K, Yoshikawa T, Aruga J
Nature communications   8 15800   Jun 2017   [Refereed]
Matsuura A, Ishima T, Fujita Y, Iwayama Y, Hasegawa S, Kawahara-Miki R, Maekawa M, Toyoshima M, Ushida Y, Suganuma H, Kida S, Yoshikawa T, Iyo M, Hashimoto K
Scientific reports   8(1) 2158   Feb 2018   [Refereed]
Balan S, Yamada K, Iwayama Y, Hashimoto T, Toyota T, Shimamoto C, Maekawa M, Takagai S, Wakuda T, Kameno Y, Kurita D, Yamada K, Kikuchi M, Hashimoto T, Kanahara N, Yoshikawa T
Schizophrenia research   185 33-40   Jul 2017   [Refereed]
Liu X, Shimada T, Otowa T, Wu YY, Kawamura Y, Tochigi M, Iwata Y, Umekage T, Toyota T, Maekawa M, Iwayama Y, Suzuki K, Kakiuchi C, Kuwabara H, Kano Y, Nishida H, Sugiyama T, Kato N, Chen CH, Mori N, Yamada K, Yoshikawa T, Kasai K, Tokunaga K, Sasaki T, Gau SS
Autism research : official journal of the International Society for Autism Research   9(3) 340-349   Mar 2016   [Refereed]
Hamazaki K, Maekawa M, Toyota T, Iwayama Y, Dean B, Hamazaki T, Yoshikawa T
Schizophrenia research   171(1-3) 225-232   Mar 2016   [Refereed]
Ebrahimi M, Yamamoto Y, Sharifi K, Kida H, Kagawa Y, Yasumoto Y, Islam A, Miyazaki H, Shimamoto C, Maekawa M, Mitsushima D, Yoshikawa T, Owada Y
Glia   64(1) 48-62   Jan 2016   [Refereed]
Maekawa M, Iwayama Y, Ohnishi T, Toyoshima M, Shimamoto C, Hisano Y, Toyota T, Balan S, Matsuzaki H, Iwata Y, Takagai S, Yamada K, Ota M, Fukuchi S, Okada Y, Akamatsu W, Tsujii M, Kojima N, Owada Y, Okano H, Mori N, Yoshikawa T
Scientific reports   6 20268   Jan 2016   [Refereed]
Maekawa M, Iwayama Y, Ohnishi T, Toyoshima M, Shimamoto C, Hisano Y, Toyota T, Balan S, Matsuzaki H, Iwata Y, Takagai S, Yamada K, Ota M, Fukuchi S, Okada Y, Akamatsu W, Tsujii M, Kojima N, Owada Y, Okano H, Mori N, Yoshikawa T
Scientific reports   5 16239   Nov 2015   [Refereed]
Hashimoto M, Maekawa M, Katakura M, Hamazaki K, Matsuoka Y
Journal of pharmacological sciences   124(3) 294-300   2014   [Refereed]
Kagawa Y, Yasumoto Y, Sharifi K, Ebrahimi M, Islam A, Miyazaki H, Yamamoto Y, Sawada T, Kishi H, Kobayashi S, Maekawa M, Yoshikawa T, Takaki E, Nakai A, Kogo H, Fujimoto T, Owada Y
Glia   63(5) 780-794   May 2015   [Refereed]
Okahara K, Kizuka Y, Kitazume S, Ota F, Nakajima K, Hirabayashi Y, Maekawa M, Yoshikawa T, Taniguchi N
Glycobiology   24(10) 926-934   Oct 2014   [Refereed]
Hamazaki K, Maekawa M, Toyota T, Dean B, Hamazaki T, Yoshikawa T
Psychiatry research   227(2-3) 353-359   Jan 2015   [Refereed]
Shimamoto C, Ohnishi T, Maekawa M, Watanabe A, Ohba H, Arai R, Iwayama Y, Hisano Y, Toyota T, Toyoshima M, Suzuki K, Shirayama Y, Nakamura K, Mori N, Owada Y, Kobayashi T, Yoshikawa T
Human molecular genetics   24(8) 2409   Apr 2015   [Refereed]
Balan S, Iwayama Y, Yamada K, Toyota T, Ohnishi T, Toyoshima M, Shimamoto C, Ide M, Iwata Y, Suzuki K, Kikuchi M, Hashimoto T, Kanahara N, Yoshikawa T, Maekawa M
Journal of neural transmission (Vienna, Austria : 1996)   122(3) 477-485   Mar 2015   [Refereed]
Shimamoto C, Ohnishi T, Maekawa M, Watanabe A, Ohba H, Arai R, Iwayama Y, Hisano Y, Toyota T, Toyoshima M, Suzuki K, Shirayama Y, Nakamura K, Mori N, Owada Y, Kobayashi T, Yoshikawa T
Human molecular genetics   23(24) 6495-6511   Dec 2014   [Refereed]
Balan S, Iwayama Y, Maekawa M, Toyota T, Ohnishi T, Toyoshima M, Shimamoto C, Esaki K, Yamada K, Iwata Y, Suzuki K, Ide M, Ota M, Fukuchi S, Tsujii M, Mori N, Shinkai Y, Yoshikawa T
Molecular autism   5(1) 49   2014   [Refereed]
Maekawa M, Yamada K, Toyoshima M, Ohnishi T, Iwayama Y, Shimamoto C, Toyota T, Nozaki Y, Balan S, Matsuzaki H, Iwata Y, Suzuki K, Miyashita M, Kikuchi M, Kato M, Okada Y, Akamatsu W, Mori N, Owada Y, Itokawa M, Okano H, Yoshikawa T
Biological psychiatry   78(2) 116-125   Sep 2014   [Refereed]
Balan S, Yamada K, Iwayama Y, Toyota T, Ohnishi T, Maekawa M, Toyoshima M, Iwata Y, Suzuki K, Kikuchi M, Ujike H, Inada T, Kunugi H, Ozaki N, Iwata N, Nanko S, Kato T, Yoshikawa T
Gene   526(2) 246-250   Sep 2013   [Refereed]
Takata A, Iwayama Y, Fukuo Y, Ikeda M, Okochi T, Maekawa M, Toyota T, Yamada K, Hattori E, Ohnishi T, Toyoshima M, Ujike H, Inada T, Kunugi H, Ozaki N, Nanko S, Nakamura K, Mori N, Kanba S, Iwata N, Kato T, Yoshikawa T
Biological psychiatry   73(6) 532-539   Mar 2013   [Refereed]
Balan S, Yamada K, Hattori E, Iwayama Y, Toyota T, Ohnishi T, Maekawa M, Toyoshima M, Iwata Y, Suzuki K, Kikuchi M, Yoshikawa T
PloS one   8(7) e70302   2013   [Refereed]
[The role of fatty acids and fatty acid binding proteins in the development of schizophrenia].
Maekawa M, Shimamoto C
Seikagaku. The Journal of Japanese Biochemical Society   84 862-866   Oct 2012   [Refereed]
Matsumata M, Sakayori N, Maekawa M, Owada Y, Yoshikawa T, Osumi N
Stem cells (Dayton, Ohio)   30(7) 1532-1543   Jul 2012   [Refereed]
Yamada K, Iwayama Y, Toyota T, Ohnishi T, Ohba H, Maekawa M, Yoshikawa T
Human genetics   131(3) 443-451   Sep 2011   [Refereed]
Sharifi K, Morihiro Y, Maekawa M, Yasumoto Y, Hoshi H, Adachi Y, Sawada T, Tokuda N, Kondo H, Yoshikawa T, Suzuki M, Owada Y
Histochemistry and cell biology   136(5) 501-513   Sep 2011   [Refereed]
Jitoku D, Hattori E, Iwayama Y, Yamada K, Toyota T, Kikuchi M, Maekawa M, Nishikawa T, Yoshikawa T
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics   156(5) 581-592   Jul 2011   [Refereed]
Sakayori N, Maekawa M, Numayama-Tsuruta K, Katura T, Moriya T, Osumi N
Genes to cells : devoted to molecular & cellular mechanisms   16(7) 778-790   Jul 2011   [Refereed]
Ohnishi T, Yamada K, Watanabe A, Ohba H, Sakaguchi T, Honma Y, Iwayama Y, Toyota T, Maekawa M, Watanabe K, Detera-Wadleigh SD, Wakana S, Yoshikawa T
PloS one   6(12) e29499   2011   [Refereed]
Maekawa M, Owada Y, Yoshikawa T
Current pharmaceutical design   17(2) 168-175   2011   [Refereed]
Yamada K, Iwayama Y, Hattori E, Iwamoto K, Toyota T, Ohnishi T, Ohba H, Maekawa M, Kato T, Yoshikawa T
PloS one   6(6) e20468   2011   [Refereed]
Maekawa M, Ohnishi T, Hashimoto K, Watanabe A, Iwayama Y, Ohba H, Hattori E, Yamada K, Yoshikawa T
Journal of neurochemistry   115(6) 1374-1385   Dec 2010   [Refereed]
Umeda T, Takashima N, Nakagawa R, Maekawa M, Ikegami S, Yoshikawa T, Kobayashi K, Okanoya K, Inokuchi K, Osumi N
PloS one   5(12) e15500   Dec 2010   [Refereed]
[Analysis of mouse strain-dependent prepulse inhibition points to a role for Shmt1 (SHMT1) in mice and in schizophrenia].
Yoshikawa T, Maekawa M, Ohnishi T, Hashimoto K, Watanabe A
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology   30(5-6) 197-200   Nov 2010   [Refereed]
Maekawa M, Iwayama Y, Watanabe A, Nozaki Y, Ohnishi T, Ohba H, Toyoshima M, Hamazaki K, Osumi N, Aruga J, Yoshikawa T
Biochemical and biophysical research communications   402(2) 431-437   Nov 2010   [Refereed]
Iwata Y, Yamada K, Iwayama Y, Anitha A, Thanseem I, Toyota T, Hattori E, Ohnishi T, Maekawa M, Nakamura K, Suzuki K, Matsuzaki H, Tsuchiya KJ, Suda S, Sugihara G, Takebayashi K, Yamamoto S, Iwata K, Mori N, Yoshikawa T
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics   153B(6) 1221-1227   Sep 2010   [Refereed]
Ohnishi T, Watanabe A, Ohba H, Iwayama Y, Maekawa M, Yoshikawa T
Neuroscience research   67(1) 86-94   May 2010   [Refereed]
Maekawa M, Fujisawa H, Iwayama Y, Tamase A, Toyota T, Osumi N, Yoshikawa T
Brain pathology (Zurich, Switzerland)   20(6) 1033-1041   May 2010   [Refereed]
Iwayama Y, Hattori E, Maekawa M, Yamada K, Toyota T, Ohnishi T, Iwata Y, Tsuchiya KJ, Sugihara G, Kikuchi M, Hashimoto K, Iyo M, Inada T, Kunugi H, Ozaki N, Iwata N, Nanko S, Iwamoto K, Okazaki Y, Kato T, Yoshikawa T
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics   153B(2) 484-493   Mar 2010   [Refereed]
Maekawa M, Iwayama Y, Arai R, Nakamura K, Ohnishi T, Toyota T, Tsujii M, Okazaki Y, Osumi N, Owada Y, Mori N, Yoshikawa T
Journal of human genetics   55(2) 127-130   Feb 2010   [Refereed]
Maekawa M, Iwayama Y, Nakamura K, Sato M, Toyota T, Ohnishi T, Yamada K, Miyachi T, Tsujii M, Hattori E, Maekawa N, Osumi N, Mori N, Yoshikawa T
Neuroscience letters   462(3) 267-271   Oct 2009   [Refereed]
Namba T, Maekawa M, Yuasa S, Kohsaka S, Uchino S
Glia   57(10) 1082-1090   Aug 2009   [Refereed]
Meerabux JM, Ohba H, Iwayama Y, Maekawa M, Detera-Wadleigh SD, DeLisi LE, Yoshikawa T
Journal of human genetics   54(7) 386-391   Jul 2009   [Refereed]
Maekawa M, Namba T, Suzuki E, Yuasa S, Kohsaka S, Uchino S
Neuroscience research   63(4) 259-266   Apr 2009   [Refereed]
Soma M, Aizawa H, Ito Y, Maekawa M, Osumi N, Nakahira E, Okamoto H, Tanaka K, Yuasa S
The Journal of comparative neurology   513(1) 113-128   Mar 2009   [Refereed]
Sekiguchi M, Zushida K, Yoshida M, Maekawa M, Kamichi S, Yoshida M, Sahara Y, Yuasa S, Takeda S, Wada K
Brain : a journal of neurology   132(Pt 1) 124-135   Jan 2009   [Refereed]
Maekawa M, Takashima N, Matsumata M, Ikegami S, Kontani M, Hara Y, Kawashima H, Owada Y, Kiso Y, Yoshikawa T, Inokuchi K, Osumi N
PloS one   4(4) e5085   2009   [Refereed]
Yamasaki N, Maekawa M, Kobayashi K, Kajii Y, Maeda J, Soma M, Takao K, Tanda K, Ohira K, Toyama K, Kanzaki K, Fukunaga K, Sudo Y, Ichinose H, Ikeda M, Iwata N, Ozaki N, Suzuki H, Higuchi M, Suhara T, Yuasa S, Miyakawa T
Molecular brain   1 6   Sep 2008   [Refereed]
Osumi N, Shinohara H, Numayama-Tsuruta K, Maekawa M
Stem cells (Dayton, Ohio)   26(7) 1663-1672   Jul 2008   [Refereed]
Watanabe A, Toyota T, Owada Y, Hayashi T, Iwayama Y, Matsumata M, Ishitsuka Y, Nakaya A, Maekawa M, Ohnishi T, Arai R, Sakurai K, Yamada K, Kondo H, Hashimoto K, Osumi N, Yoshikawa T
PLoS biology   5(11) e297   Nov 2007   [Refereed]

Misc

 
島本知英, 江崎加代子, 岩山佳美, 大西哲生, 前川素子, 豊島学, 吉川武男
統合失調症研究   8(1) 93   Mar 2018
前川 素子, 和田 唯奈
生体の科学   67(5) 486-487   Oct 2016
統合失調症の診断を補助,あるいは疾患を層別化するバイオマーカーを探索する試料として,脳と同じ外胚葉由来の組織であり,また,代謝的に安定していると考えられる"頭皮の毛根細胞"に着目し解析した。その結果,脳特異的と想定されていた遺伝子の多くが毛根でも発現していること,統合失調症ではFABP4遺伝子の発現量が約40%低下していること,FABP4の発現量の低下は年齢,性別,服薬,疾患罹患期間に影響されないことがわかった。毛根におけるFABP4遺伝子は統合失調症のバイオマーカーとして期待される。(著...
前川素子, 吉川武男
日本解剖学会総会・全国学術集会講演プログラム・抄録集   123rd 91   2018
前川素子, 吉川武男
日本精神神経学会総会プログラム・抄録集   114th S.469   2018
前川素子, 大西哲生, 豊島学, 豊田倫子, 松崎秀夫, 森則夫, 吉川武男
先進医薬研究振興財団研究成果報告集   2016 46‐47-47   Mar 2017

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(若手研究(B))
Project Year: 2011 - 2012    Investigator(s): Motoko MAEKAWA
Schizophrenia is a debilitating mental disorder that afflicts about 1% of the population worldwide. Despite intensive and multifaceted research, its exact etiology remains largely elusive. The neurodevelopmental hypothesis of schizophrenia suggest...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(若手研究(B))
Project Year: 2009 - 2010    Investigator(s): Motoko MAEKAWA
In mice fed polyunsaturated fatty acids (PUFAs)-deficient diet during the brain developmental stage, we observed broad downregulation of genes related to oligodendrocyte and GABAergic systems, which is a current theory of functional psychoses. Mor...