論文

査読有り
2013年

Successful Treatment of Severe Newly Diagnosed Immune Thrombocytopenia Involving an Alveolar Hemorrhage with Combination Therapy Consisting of Romiplostim, Rituximab and Vincristine

INTERNAL MEDICINE
  • Kiyoshi Okazuka
  • Masayoshi Masuko
  • Yuji Matsuo
  • Shukuko Miyakoshi
  • Tomoyuki Tanaka
  • Takashi Kozakai
  • Hironori Kobayashi
  • Kyoko Fuse
  • Yasuhiko Shibasaki
  • Masato Moriyama
  • Jun Takizawa
  • Ichiro Fuse
  • Ken Toba
  • Tatsuo Furukawa
  • 全て表示

52
11
開始ページ
1239
終了ページ
1242
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.2169/internalmedicine.52.0080
出版者・発行元
JAPAN SOC INTERNAL MEDICINE

A 51-year-old man was admitted due to a severe bleeding tendency. After he was diagnosed with immune thrombocytopenia (ITP), several therapies, including steroids, steroid pulse, vincristine and rituximab, were administered; however, the patient's bleeding symptoms were not sufficiently controllable with these treatments. Subsequently, a diffuse alveolar hemorrhage was observed. Treatment with a thrombopoietin receptor agonist, romiplostim, was initiated to prevent lethal hemorrhaging, although the efficacy of thrombopoietic receptor agonists in such emergency situations has not been elucidated. The initiation of romiplostim achieved prompt remission in platelets. This case suggests that combination therapy with romiplostim, rituximab and vincristine is effective in cases of newly diagnosed severe therapy-resistant ITP.

リンク情報
DOI
https://doi.org/10.2169/internalmedicine.52.0080
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000320873900016&DestApp=WOS_CPL
ID情報
  • DOI : 10.2169/internalmedicine.52.0080
  • ISSN : 0918-2918
  • Web of Science ID : WOS:000320873900016

エクスポート
BibTeX RIS