大谷木正貴 (Masaki Ohyagi) - マイポータル

基本情報

所属: 慶應義塾大学医学部微生物学免疫学教室特任助教

学位: 医学(2020年3月東京医科歯科大学)

研究者番号: 70882497
ORCID ID: https://orcid.org/0000-0002-6009-450X
J-GLOBAL ID: 202001003537921710
researchmap会員ID: R000003286

学歴

2015年4月 - 2020年3月

東京医科歯科大学大学院医歯学総合研究科脳神経病態学分野
2002年4月 - 2008年3月

東京医科歯科大学医学部医学科

受賞

2021年4月

the Oral Presentation Silver Award New therapeutic strategy for multiple sclerosis (MS) by DNA/RNA heteroduplex oligonucleotide technology 第17回アジア・オセアニア神経学会議
2020年9月

AOCN2021演題発表支援トラベルグラント New therapeutic strategy for multiple sclerosis by DNA/RNA heteroduplex oligonucleotide technology 日本神経学会
2019年9月

Young Neuroimmunologist Award DNA/RNAヘテロ2本鎖核酸によるリンパ球制御を介した神経免疫疾患の新規治療法の開発日本神経免疫学会

論文

Anti-human-TIGIT agonistic antibody ameliorates autoimmune diseases by inhibiting Tfh and Tph cells and enhancing Treg cells.

Marenori Kojima, Katsuya Suzuki, Masaru Takeshita, Masaki Ohyagi, Mana Iizuka, Humitsugu Yamane, Keiko Koga, Taku Kouro, Yoshiaki Kassai, Tomoki Yoshihara, Ryutaro Adachi, Kentarou Hashikami, Yuichiro Ota, Keiko Yoshimoto, Yuko Kaneko, Rimpei Morita, Akihiko Yoshimura, Tsutomu Takeuchi

Communications biology 6(1) 500-500 2023年5月9日
T cells in the brain inflammation.

Akihiko Yoshimura, Masaki Ohyagi, Minako Ito

Advances in immunology 157 29-58 2023年
Memory B Cells and Memory T Cells Induced by SARS-CoV-2 Booster Vaccination or Infection Show Different Dynamics and Responsiveness to the Omicron Variant.

Setsuko Mise-Omata, Mari Ikeda, Masaru Takeshita, Yoshifumi Uwamino, Masatoshi Wakui, Tomoko Arai, Ayumi Yoshifuji, Kensaku Murano, Haruhiko Siomi, Kensuke Nakagawara, Masaki Ohyagi, Makoto Ando, Naoki Hasegawa, Hideyuki Saya, Mitsuru Murata, Koichi Fukunaga, Ho Namkoong, Xiuyuan Lu, Sho Yamasaki, Akihiko Yoshimura

Journal of immunology (Baltimore, Md. : 1950) 209(11) 2104-2113 2022年12月1日
Systemic DNA/RNA heteroduplex oligonucleotide administration for regulating the gene expression of dorsal root ganglion and sciatic nerve.

Hidetoshi Kaburagi, Tetsuya Nagata, Mitsuhiro Enomoto, Takashi Hirai, Masaki Ohyagi, Kensuke Ihara, Kie Yoshida-Tanaka, Satoe Ebihara, Ken Asada, Hiroyuki Yokoyama, Atsushi Okawa, Takanori Yokota

Molecular therapy. Nucleic acids 28 910-919 2022年6月14日査読有り
Regulation of activated microglia and macrophages by systemically administered DNA/RNA heteroduplex oligonucleotides.

Rieko Nishi, Masaki Ohyagi, Tetsuya Nagata, Yo Mabuchi, Takanori Yokota

Molecular therapy : the journal of the American Society of Gene Therapy 30(6) 2210-2223 2022年2月18日査読有り筆頭著者
DNA/RNA heteroduplex oligonucleotide technology for regulating lymphocytes in vivo.

Masaki Ohyagi, Tetsuya Nagata, Kensuke Ihara, Kie Yoshida-Tanaka, Rieko Nishi, Haruka Miyata, Aya Abe, Yo Mabuchi, Chihiro Akazawa, Takanori Yokota

Nature communications 12(1) 7344-7344 2021年12月22日査読有り筆頭著者
Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood–brain barrier and knock down genes in the rodent CNS

Tetsuya Nagata, Chrissa A. Dwyer, Kie Yoshida-Tanaka, Kensuke Ihara, Masaki Ohyagi, Hidetoshi Kaburagi, Haruka Miyata, Satoe Ebihara, Kotaro Yoshioka, Takashi Ishii, Kanjiro Miyata, Kenichi Miyata, Berit Powers, Tomoko Igari, Syunsuke Yamamoto, Naoto Arimura, Hideki Hirabayashi, Toshiki Uchihara, Rintaro Iwata Hara, Takeshi Wada, C. Frank Bennett, Punit P. Seth, Frank Rigo, Takanori Yokota

Nature Biotechnology 39(12) 1529-1536 2021年12月査読有り
Intrathecal IgG Synthesis and Persistent Inflammation Are Associated with White Matter Lesions in HIV-negative Patients with Cryptococcal Meningoencephalitis.

Masaki Ohyagi, Takashi Irioka, Takuya Ohkubo, Satoru Ishibashi, Yuko K Takahashi, Eiichiro Amano, Akira Machida, Hiroya Kuwahara, Takanori Yokota

Internal medicine (Tokyo, Japan) 58(21) 3077-3082 2019年11月1日査読有り筆頭著者
Subacute Supranuclear Palsy in anti-Hu Paraneoplastic Encephalitis.

Masaki Ohyagi, Satoru Ishibashi, Takuya Ohkubo, Zen Kobayashi, Hidehiro Mizusawa, Takanori Yokota, Hirofumi Emoto, Motohiro Kiyosawa

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 44(4) 444-446 2017年7月査読有り筆頭著者
Embolic stroke during apixaban therapy for left atrial appendage thrombus.

Masaki Ohyagi, Kazuha Nakamura, Mutsufusa Watanabe, Hiroto Fujigasaki

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 24(4) e101-2 2015年4月査読有り筆頭著者
Porencephaly in a fetus and HANAC in her father: variable expression of COL4A1 mutation.

Toshiki Takenouchi, Masaki Ohyagi, Chiharu Torii, Rika Kosaki, Takao Takahashi, Kenjiro Kosaki

American journal of medical genetics. Part A 167A(1) 156-8 2015年1月査読有り
Chronic inflammatory demyelinating polyradiculoneuropathy in a patient with Crohn's disease.

Masaki Ohyagi, Takuya Ohkubo, Yousuke Yagi, Satoru Ishibashi, Junko Akiyama, Masakazu Nagahori, Mamoru Watanabe, Takanori Yokota, Hidehiro Mizusawa

Internal medicine (Tokyo, Japan) 52(1) 125-8 2013年査読有り筆頭著者
Progression of bilateral internal carotid artery dissection during antiplatelet therapy.

Masaki Ohyagi, Osamu Tao, Tohru Mizutani, Mafuyu Takahashi, Hidehiro Mizusawa

Internal medicine (Tokyo, Japan) 52(24) 2821-3 2013年査読有り筆頭著者
Hereditary neuropathy with liability to pressure palsy combined with suspected schwannomas of the peroneal and radial nerves.

Masaki Ohyagi, Nobuo Sanjo, Takanori Yokota, Hidehiro Mizusawa

Journal of neurology 259(5) 977-9 2012年5月査読有り筆頭著者
Spinal epidural abscess caused by bacteroides fragilis group after dilation and curettage for incomplete abortion.

Masaki Ohyagi, Takuya Ohkubo, Takashi Taniyama, Shoji Tomizawa, Atsushi Okawa, Takanori Yokota, Hidehiro Mizusawa

Journal of global infectious diseases 4(2) 132-4 2012年4月査読有り筆頭著者
Regulation of angiogenesis in the bone marrow of myelodysplastic syndromes transforming to overt leukaemia.

Tamara Keith, Yuko Araki, Masaki Ohyagi, Maki Hasegawa, Kouhei Yamamoto, Morito Kurata, Yasunori Nakagawa, Kenshi Suzuki, Masanobu Kitagawa

British journal of haematology 137(3) 206-15 2007年5月査読有り