Shimagaki T, Yoshio S, Kawai H, Sakamoto Y, Doi H, Matsuda M, Mori T, Osawa Y, Fukai M, Yoshida T, Ma Y, Akita T, Tanaka J, Taketomi A, Hanayama R, Yoshizumi T, Mori M, Kanto T
Sawai H, Nishida N, Khor SS, Honda M, Sugiyama M, Baba N, Yamada K, Sawada N, Tsugane S, Koike K, Kondo Y, Yatsuhashi H, Nagaoka S, Taketomi A, Fukai M, Kurosaki M, Izumi N, Kang JH, Murata K, Hino K, Nishina S, Matsumoto A, Tanaka E, Sakamoto N, Ogawa K, Yamamoto K, Tamori A, Yokosuka O, Kanda T, Sakaida I, Itoh Y, Eguchi Y, Oeda S, Mochida S, Yuen MF, Seto WK, Poovorawan Y, Posuwan N, Mizokami M, Tokunaga K
Shoji H, Yoshio S, Mano Y, Kumagai E, Sugiyama M, Korenaga M, Arai T, Itokawa N, Atsukawa M, Aikata H, Hyogo H, Chayama K, Ohashi T, Ito K, Yoneda M, Nozaki Y, Kawaguchi T, Torimura T, Abe M, Hiasa Y, Fukai M, Kamiyama T, Taketomi A, Mizokami M, Kanto T
Ichikawa N, Yamashita K, Funakoshi T, Ichihara S, Fukai M, Ogura M, Kobayashi N, Zaitsu M, Yoshida T, Shibasaki S, Koshizuka Y, Tsunetoshi Y, Sato M, Einama T, Ozaki M, Umezawa K, Suzuki T, Todo S
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 65(3) 245-260 Mar 2016 [Refereed]
Fujiyoshi M, Kuno A, Gotoh M, Fukai M, Yokoo H, Kamachi H, Kamiyama T, Korenaga M, Mizokami M, Narimatsu H, Taketomi A, Hepatitis Glyco-biomarker Study Group
Journal of gastroenterology 50(11) 1134-1144 Mar 2015 [Refereed]
Donor shortage has been an unresolved problem in clinical transplantation. It is difficult to enlarge donor pool to the expanded criteria donor(ECD)by simple cold storage, due to the severe ischemia and reperfusion injury (IRI). Resuscitation of t...
It is no doubt that a new methodology to repair grafts from extended criteria donor(ECD)is necessary in a clinical settings of organ transplantation. The superiority of organ perfusion, to cold storage, is generally accepted in ECD grafts. However...
Although organ cooling is beneficial for any kind of grafts, mainly by metabolic arrest, hypoxia and hypothermia concomitantly cause harmful reactions, such as ATP depletion, mitochondrial dysfunction, cytosolic Ca2＋ overload, intracellular acidos...
Heavy water, deuterium oxide(D2O), is a stable isotope compound of H2O, causing stabilization of actin and tubulin. D2O inhibits cytosolic calcium overload via plasma membrane channel and ER. D2O stimulates ATP production by augmenting glucose upt...
In order to develop an effective organ/cell preservation solution and to monitor graft function continuously and non-invasively, an innovative imaging technology to visualize cell/organ function is required. Recently, we developed molecular probes...
The journal of the Japanese Association for Chest Surgery 17(5) 570-573 Jul 2003
Here we report a case of intralobar pulmonary sequestration resected by thoracoscopic surgery. A 38-year-old woman was admitted to our hospital with an abnormal shadow in the right lower lung field on chest X-ray. Chest CT and angiography were don...
The journal of the Japanese Association for Chest Surgery 17(4) 495-499 May 2003
We report two cases of postoperative bronchial fistula successfully treated by endoscopic closure with coils and fibrin glue. Patient 1 was a 65-year-old man with diabetes and old myocardial infarction. He underwent right lower lobectomy for lung ...
The journal of the Japanese Association for Chest Surgery 17(4) 505-510 May 2003
A 50-year-old man was admitted to our hospital with abdominal pain due to urinary stone. High serum levels of Ca, intact PTH. And high-sensitivity PTH suggested hyper-parathyroidism. ^<99m>Tc-MIBI scintigram showed abnormal uptake in the upper med...
We confirmed that the superiority of the novel solution over UW solution for the use of simple cold preservation in rat liver and heart, due to the inhibition of cytosolic Ca2+ overload and cytoskeletal breakdown, and stimulation of aerobic respir...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(A))
Project Year: 2010 - 2012 Investigator(s): Satoru TODO
We explored the necessary condition of heavy water containing buffer for the use of simple cold preservation. The novel solution appeared to show excellent cytoprotection in various cells, and rat liver and heart, due to the inhibition of cytosoli...
