2011年8月
Establishment and Characterization of Canine Rhabdomyosarcoma Cell Line CMS-C
JOURNAL OF VETERINARY MEDICAL SCIENCE
- 巻
- 73
- 号
- 8
- 開始ページ
- 1105
- 終了ページ
- 1108
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1292/jvms.10-0436
- 出版者・発行元
- JAPAN SOC VET SCI
A novel canine tumor cell line designated as the CMS-C cell line was established from pleomorphic rhabdomyosarcoma (RMS) raised in the prostate gland of a 14-year-old intact male mixed-breed dog. CMS-C cells displayed the same immunohistochemical characteristics (positive for vimentin and desmin and negative for cytokeratin and smooth muscle actin) as the original tumor cells and express myoD1 and UCP3, known as striated muscle-specific molecules, as shown by RT-PCR assay. Therefore, the established CMS-C cell line appears to be of rhabdomyoblast cell origin. The CMS-C cell line established from pleomorphic RMS will be a useful tool for further studies about canine RMS.
- リンク情報
- ID情報
-
- DOI : 10.1292/jvms.10-0436
- ISSN : 0916-7250
- PubMed ID : 21519159
- Web of Science ID : WOS:000294792300023