篠原基子 (Motoko Shinohara) - マイポータル

基本情報

所属: 藤田医科大学感染症研究センター

研究者番号: 71013744
ORCID iD: https://orcid.org/0000-0001-7111-8012
J-GLOBAL ID: 202401001157209444
researchmap会員ID: R000079950

論文

Integrated analysis of Tn-Seq and pangenome reveals core and lineage-specific essential genes in Mycobacterium avium subsp. hominissuis

Kotaro Sawai, Marie Ikai, Motoko Shinohara, Yukiko Nishiuchi, So Fujiyoshi, Yohei Doi, Tomotada Iwamoto, Kentaro Arikawa, Fumito Maruyama, Yusuke Minato

2025年10月13日
Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY.

Takeshi Nakaya, Miyuki Yabe, Ellene H Mashalidis, Toyotaka Sato, Kazuki Yamamoto, Yuta Hikiji, Akira Katsuyama, Motoko Shinohara, Yusuke Minato, Satoshi Takahashi …

Nature communications 13(1) 7575-7575 2022年12月20日
Synthesis of capuramycin and its analogues via a Ferrier-type I reaction and their biological evaluation.

Shintaro Kusaka, Kazuki Yamamoto, Motoko Shinohara, Yusuke Minato, Satoshi Ichikawa

Bioorganic & medicinal chemistry 73 117011-117011 2022年11月1日
Design, synthesis and conformation-activity relationship analysis of LNA/BNA-type 5'-O-aminoribosyluridine as MraY inhibitors.

Shintaro Kusaka, Kazuki Yamamoto, Motoko Shinohara, Yusuke Minato, Satoshi Ichikawa

Bioorganic & medicinal chemistry 65 116744-116744 2022年7月1日
APOE2 is associated with longevity independent of Alzheimer's disease.

Mitsuru Shinohara, Takahisa Kanekiyo, Masaya Tachibana, Aishe Kurti, Motoko Shinohara, Yuan Fu, Jing Zhao, Xianlin Han, Patrick M Sullivan, G William Rebeck …

eLife 9 2020年10月19日
Increased levels of Aβ42 decrease the lifespan of ob/ob mice with dysregulation of microglia and astrocytes.

Mitsuru Shinohara, Yoshitaka Tashiro, Motoko Shinohara, Junko Hirokawa, Kaoru Suzuki, Miyuki Onishi-Takeya, Masahiro Mukouzono, Shuko Takeda, Takashi Saito, Akio Fukumori …

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 34(2) 2425-2435 2020年2月
Selective loss of cortical endothelial tight junction proteins during Alzheimer's disease progression.

Yu Yamazaki, Mitsuru Shinohara, Motoko Shinohara, Akari Yamazaki, Melissa E Murray, Amanda M Liesinger, Michael G Heckman, Elizabeth R Lesser, Joseph E Parisi, Ronald C Petersen …

Brain : a journal of neurology 142(4) 1077-1092 2019年4月1日
5-HT3 Antagonist Ondansetron Increases apoE Secretion by Modulating the LXR-ABCA1 Pathway.

Motoko Shinohara, Mitsuru Shinohara, Jing Zhao, Yuan Fu, Chia-Chen Liu, Takahisa Kanekiyo, Guojun Bu

International journal of molecular sciences 20(6) 2019年3月25日
Distinct spatiotemporal accumulation of N-truncated and full-length amyloid-β42 in Alzheimer's disease.

Mitsuru Shinohara, Shunsuke Koga, Takuya Konno, Jeremy Nix, Motoko Shinohara, Naoya Aoki, Pritam Das, Joseph E Parisi, Ronald C Petersen, Terrone L Rosenberry …

Brain : a journal of neurology 140(12) 3301-3316 2017年12月1日
Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer's disease.

Mitsuru Shinohara, Melissa E Murray, Ryan D Frank, Motoko Shinohara, Michael DeTure, Yu Yamazaki, Masaya Tachibana, Yuka Atagi, Mary D Davis, Chia-Chen Liu …

Acta neuropathologica 132(2) 225-234 2016年8月
APOE2 eases cognitive decline during Aging: Clinical and preclinical evaluations.

Mitsuru Shinohara, Takahisa Kanekiyo, Longyu Yang, Duane Linthicum, Motoko Shinohara, Yuan Fu, Laura Price, Jessica L Frisch-Daiello, Xianlin Han, John D Fryer …

Annals of neurology 79(5) 758-774 2016年5月
Neuronal clearance of amyloid-β by endocytic receptor LRP1.

Takahisa Kanekiyo, John R Cirrito, Chia-Chen Liu, Mitsuru Shinohara, Jie Li, Dorothy R Schuler, Motoko Shinohara, David M Holtzman, Guojun Bu

The Journal of neuroscience : the official journal of the Society for Neuroscience 33(49) 19276-83 2013年12月4日