論文

査読有り 国際誌
2017年2月15日

Bordetella pertussis infection in children with severe pneumonia, Philippines, 2012-2015.

Vaccine
  • Alexander Sadiasa
  • ,
  • Mariko Saito-Obata
  • ,
  • Clyde Dapat

35
7
開始ページ
993
終了ページ
996
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.vaccine.2016.11.087

A case-comparison study was conducted based on an observational study of severe pneumonia among hospitalized children in the Philippines. The children, from 8days to 13years old and hospitalized with clinical diagnosis of severe or very severe pneumonia from August 2012 to February 2015, were recruited. Nasopharyngeal swabs were collected from 1152 cases and B. pertussis were detected from 34 cases by PCR. Pertussis-positive cases were more likely to have no fever, more than one week of coughing and breathing difficulty, decreased breathing sounds, and central cyanosis than pertussis- negative cases. The percentage of underweight was significantly higher in pertussis-positive cases than pertussis-negative cases. Pertussis-positive cases showed remarkably higher fatality rate than pertussis-negative cases. All of the fatal cases among pertussis-positive cases were less than 6months old. More attention should be given to protect young infants from pertussis.

リンク情報
DOI
https://doi.org/10.1016/j.vaccine.2016.11.087
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/28109708
ID情報
  • DOI : 10.1016/j.vaccine.2016.11.087
  • ISSN : 0264-410X
  • PubMed ID : 28109708

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