得能正裕 (Masahiro Tokuno) - マイポータル

基本情報

所属: 崇城大学薬学部薬学科助教

学位: 博士（薬学）

ORCID iD: https://orcid.org/0009-0009-6867-4574
J-GLOBAL ID: 202501006649244031
researchmap会員ID: R000084302

研究分野

ライフサイエンス / 医療薬学 /

論文

Mechanistic Insights into pH-Responsive Drug Release and Antitumor Effects of an Albumin-Pirarubicin Conjugate

Kenji Tsukigawa, Shuhei Imoto, Kotone Imamura, Naoki Irie, Koji Nishi, Masahiro Tokuno, Kindness Lomotey Commey, Hiroshi Watanabe, Toru Maruyama, Masaki Otagiri …

Pharmaceutical Research 2026年3月23日
Caspase-Independent Cell Death Induced by a Nitric Oxide Donor Derived from Valproic Acid in Human Pancreatic Cancer Cells.

Koji Nishi, Ayaka Ueda, Takuro Beppu, Kaho Takasaki, Shuhei Imoto, Kenji Tsukikawa, Masahiro Tokuno, Masaki Otagiri, Keishi Yamasaki

Biological & pharmaceutical bulletin 49(3) 452-456 2026年
Insights into the renal protective effects of 7-phenylheptanoic acid in chronic kidney disease mice: Modulation of indoxyl sulfate production and gut microbiome homeostasis

Masahiro Tokuno, Kindness Lomotey Commey, Asami Yamamoto, Maho Tokushige, Kenji Tsukigawa, Koji Nishi, Masaki Otagiri, Keisuke Ekino, Keishi Yamasaki

Drug Metabolism and Disposition 53(10) 100149-100149 2025年10月
Insights into Dual Binding Modes of Nateglinide to Human Serum Albumin.

Akito Kawai, Koji Nishi, Masahiro Tokuno, Masaki Otagiri, Keishi Yamasaki

ACS medicinal chemistry letters 16(8) 1619-1625 2025年8月14日
Qualitative and quantitative status of cytochrome P450s after the administration of a liposomal platelet substitute in rat liver.

Kazuaki Taguchi, Mai Hashimoto, Masahiro Tokuno, Shinji Takeoka, Toru Maruyama, Keishi Yamasaki, Masaki Otagiri

Xenobiotica; the fate of foreign compounds in biological systems 54(9) 624-628 2024年9月
Possible Involvement of Protein Binding Inhibition in Changes in Dexmedetomidine Concentration in Extracorporeal Circuits during Midazolam Use.

Keishi Yamasaki, Masahiro Tokuno, Kenji Tsukigawa, Yuka Nagatsuka, Koji Nishi, Masaki Otagiri, Yuhki Sato

Biological & pharmaceutical bulletin 47(2) 389-393 2024年
Hepatic Cytochrome P450 Profiles in Hemorrhagic Shock Model Rats After Transfusion With Stored Red Blood Cells.

Masahiro Tokuno, Kazuaki Taguchi, Keishi Yamasaki, Masaki Otagiri

Journal of pharmaceutical sciences 109(11) 3490-3495 2020年11月
Assessing cytochrome P450-based drug-drug interactions with hemoglobin-vesicles, an artificial red blood cell preparation, in healthy rats.

Masahiro Tokuno, Kazuaki Taguchi, Hiromi Sakai, Sumio Ohtsuki, Keishi Yamasaki, Masaki Otagiri

Drug metabolism and pharmacokinetics 35(5) 425-431 2020年10月
Evaluation of cytochrome P450-based drug metabolism in hemorrhagic shock rats that were transfused with native and an artificial red blood cell preparation, Hemoglobin-vesicles.

Masahiro Tokuno, Kazuaki Taguchi, Hiromi Sakai, Sumio Ohtsuki, Keishi Yamasaki, Masaki Otagiri

Drug metabolism and pharmacokinetics 35(5) 417-424 2020年10月
Long-Term Stored Hemoglobin-Vesicles, a Cellular Type of Hemoglobin-Based Oxygen Carrier, Has Resuscitative Effects Comparable to That for Fresh Red Blood Cells in a Rat Model with Massive Hemorrhage without Post-Transfusion Lung Injury.

Masahiro Tokuno, Kazuaki Taguchi, Keishi Yamasaki, Hiromi Sakai, Masaki Otagiri

PloS one 11(10) e0165557 2016年
Establishment of a model of acetaminophen-induced hepatotoxicity in different weekly-aged ICR mice.

K Taguchi, M Tokuno, K Yamasaki, D Kadowaki, H Seo, M Otagiri

Laboratory animals 49(4) 294-301 2015年10月
An evaluation of novel biological activity in a crude extract from Hemerocallis fulva L. var. sempervirens M. Hotta.

Kazuaki Taguchi, Keishi Yamasaki, Hiroki Maesaki, Masahiro Tokuno, Shoko Okazaki, Hiroshi Moriuchi, Keizo Takeshita, Masaki Otagiri, Hakaru Seo

Natural product research 28(23) 2211-3 2014年

得能正裕

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