論文

査読有り
2015年12月

Zscan10 is dispensable for maintenance of pluripotency in mouse embryonic stem cells

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
  • Mariko Yamane
  • ,
  • Setsuko Fujii
  • ,
  • Satoshi Ohtsuka
  • ,
  • Hitoshi Niwa

468
4
開始ページ
826
終了ページ
831
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.bbrc.2015.11.039
出版者・発行元
ACADEMIC PRESS INC ELSEVIER SCIENCE

Zinc finger and SCAN domain-containing 10 (Zscan10, also known as Zfp206) encodes a transcription factor that has been reported to be involved in the maintenance of pluripotency in mouse embryonic stem (ES) cells. Here we generated inducible knockout ES cells for Zscan10 using the Cre-loxP system and analyzed its function. We succeeded in establishing Zscan10-null ES cells and confirmed their pluripotency by the generation of chimeric embryos. Our results clearly indicate that Zscan10 is dispensable for the ability of self-renewal and differentiation in ES cells. (C) 2015 Elsevier Inc. All rights reserved.

Web of Science ® 被引用回数 : 5

リンク情報
DOI
https://doi.org/10.1016/j.bbrc.2015.11.039
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/26592664
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000367868500049&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/j.bbrc.2015.11.039
  • ISSN : 0006-291X
  • eISSN : 1090-2104
  • PubMed ID : 26592664
  • Web of Science ID : WOS:000367868500049

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