2017年3月
Glasgow prognostic score is a prognosis predictor for patients with endometrial cancer.
European journal of obstetrics, gynecology, and reproductive biology
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- 巻
- 210
- 号
- 開始ページ
- 355
- 終了ページ
- 359
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.ejogrb.2017.01.024
OBJECTIVE: This study investigated whether the inflammation-based Glasgow prognostic score (GPS) predicted the prognosis of patients with endometrial cancer (EC) in terms of progression-free survival (PFS) and overall survival (OS). STUDY DESIGN: Pretreatment GPS was examined to determine the correlations with recurrence and survival in 431 patients with EC. Statistical analyses were performed using the Mann-Whitney U test. PFS and OS were analyzed using the Kaplan-Meier method. Cox's proportional hazard regression was used for univariate and multivariate analyses. RESULTS: Median PFS and OS were 49.7 and 52.7 months, respectively. The follow-up range was 1 to 140 months. Kaplan-Meier analysis revealed that patients with EC cancer and high GPS (GPS 2) had a shorter PFS and OS than those with lower GPS (GPS 0+1) (PFS: P<0.001; OS; P<0.001). On multivariate analysis, GPS (GPS 2) was an independent predictor of both recurrence (P<0.001) and survival (P<0.001) for all cases of EC. CONCLUSION: GPS can be useful as an indicator of poor prognosis in patients with EC.
- リンク情報
- ID情報
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- DOI : 10.1016/j.ejogrb.2017.01.024
- PubMed ID : 28129563